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Protein
Submitted name:

5'-AMP-activated protein kinase subunit beta-2

Gene

Prkab2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-1632852. Macroautophagy.
R-RNO-163680. AMPK inhibits chREBP transcriptional activation activity.
R-RNO-200425. Import of palmitoyl-CoA into the mitochondrial matrix.
R-RNO-380972. Energy dependent regulation of mTOR by LKB1-AMPK.
R-RNO-5628897. TP53 Regulates Metabolic Genes.
R-RNO-6804756. Regulation of TP53 Activity through Phosphorylation.

Names & Taxonomyi

Protein namesi
Submitted name:
5'-AMP-activated protein kinase subunit beta-2Imported
Submitted name:
Prkab2 proteinImported
Gene namesi
Name:Prkab2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi620905. Prkab2.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSRNOG00000018166.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 160AMPK1_CBMInterPro annotationAdd BLAST84

Phylogenomic databases

eggNOGiKOG1616. Eukaryota.
ENOG410XRB3. LUCA.
GeneTreeiENSGT00390000001416.
HOGENOMiHOG000230597.
HOVERGENiHBG050430.
TreeFamiTF313827.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR032640. AMPK1_CBM.
IPR030081. AMPK_beta-2.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
PANTHERiPTHR10343:SF79. PTHR10343:SF79. 1 hit.
PfamiView protein in Pfam
PF16561. AMPK1_CBM. 1 hit.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

G3V9X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNTTSERVS GERHGAKAAR AEGGGHGPGK EHKIMVGSTD DPSVFSLPDS
60 70 80 90 100
KLPGDKEFVP WQQDLDDSVK PTQQARPTVI RWSEGGKEVF ISGSFNNWST
110 120 130 140 150
KIPLIKSHND FVAILDLPEG EHQYKFFVDG QWVHDPSEPV VTSQLGTINN
160 170
LIHVKKSDFE VFDALKLDSM ESSETSCRV
Length:179
Mass (Da):19,749
Last modified:July 22, 2015 - v2
Checksum:i56EF351AC35416D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121381 Genomic DNA. No translation available.
BC078821 mRNA. Translation: AAH78821.1.
UniGeneiRn.207202.

Genome annotation databases

EnsembliENSRNOT00000063783; ENSRNOP00000062137; ENSRNOG00000018166.

Similar proteinsi

Entry informationi

Entry nameiG3V9X3_RAT
AccessioniPrimary (citable) accession number: G3V9X3
Secondary accession number(s): Q6AYZ8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: July 22, 2015
Last modified: August 30, 2017
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported