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Protein
Submitted name:

B2 bradykinin receptor

Gene

Bdkrb2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-RNO-375276. Peptide ligand-binding receptors.
R-RNO-416476. G alpha (q) signalling events.
R-RNO-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
B2 bradykinin receptorImported
Submitted name:
Bradykinin receptor, beta 2, isoform CRA_bImported
Gene namesi
Name:Bdkrb2Imported
ORF Names:rCG_27741Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi2201. Bdkrb2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei70 – 91HelicalSequence analysisAdd BLAST22
Transmembranei103 – 122HelicalSequence analysisAdd BLAST20
Transmembranei142 – 160HelicalSequence analysisAdd BLAST19
Transmembranei181 – 202HelicalSequence analysisAdd BLAST22
Transmembranei233 – 254HelicalSequence analysisAdd BLAST22
Transmembranei275 – 299HelicalSequence analysisAdd BLAST25
Transmembranei319 – 342HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000047300.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 339G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST259

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410INT3. Eukaryota.
ENOG41117RA. LUCA.
GeneTreeiENSGT00760000119055.
OMAiENSMGTL.
OrthoDBiEOG091G0AAK.
TreeFamiTF330024.

Family and domain databases

InterProiView protein in InterPro
IPR001504. Brdyknn_2_rcpt.
IPR000496. Brdyknn_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00425. BRADYKININR.
PR00994. BRADYKINNB2R.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3V942-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTRSSLCPK TQAVVEVAMF WGPGCHLSTC IEMFNITTQA LGSAHNGTFS
60 70 80 90 100
EVNCPDTEWW SWLNAIQAPF LWVLFLLAAL ENIFVLSVFC LHKTNCTVAE
110 120 130 140 150
IYLGNLAAAD LILACGLPFW AITIANNFDW LFGEVLCRVV NTMIYMNLYS
160 170 180 190 200
SICFLMLVSI DRYLALVKTM SMGRMRGVRW AKLYSLVIWS CTLLLSSPML
210 220 230 240 250
VFRTMKDYRE EGHNVTACVI VYPSRSWEVF TNMLLNLVGF LLPLSIITFC
260 270 280 290 300
TVRIMQVLRN NEMKKFKEVQ TEKKATVLVL AVLGLFVLCW FPFQISTFLD
310 320 330 340 350
TLLRLGVLSG CWNERAVDIV TQISSYVAYS NSCLNPLVYV IVGKRFRKKS
360 370 380 390
REVYQAICRK GGCMGESVQM ENSMGTLRTS ISVDRQIHKL QDWAGNKQ
Length:398
Mass (Da):45,190
Last modified:November 16, 2011 - v1
Checksum:i0D922543AF71C48B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065460 Genomic DNA. No translation available.
AABR07073260 Genomic DNA. No translation available.
AC125847 Genomic DNA. No translation available.
CH474034 Genomic DNA. Translation: EDL97607.1.
RefSeqiNP_001257642.1. NM_001270713.2.
UniGeneiRn.9845.

Genome annotation databases

EnsembliENSRNOT00000074621; ENSRNOP00000064990; ENSRNOG00000047300.
GeneIDi25245.

Similar proteinsi

Entry informationi

Entry nameiG3V942_RAT
AccessioniPrimary (citable) accession number: G3V942
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported