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Protein
Submitted name:

Kelch-like ECH-associated protein 1

Gene

Keap1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Kelch-like ECH-associated protein 1Imported
Gene namesi
Name:Keap1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi621619. Keap1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiG3V8U2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000020878.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028360.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini77 – 14973BTB (POZ)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 BTB (POZ) domain.UniRule annotation
Contains Kelch repeats.SAAS annotation

Keywords - Domaini

Kelch repeatSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
GeneTreeiENSGT00760000118931.
KOiK10456.
OMAiRSHGMLT.
OrthoDBiEOG091G02T3.
TreeFamiTF329218.

Family and domain databases

Gene3Di2.130.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR015916. Gal_Oxidase_b-propeller.
IPR030563. KEAP1.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PANTHERiPTHR24412:SF162. PTHR24412:SF162. 1 hit.
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 6 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3V8U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPEPKPSGA PRSSQFLPLW SKCPEGAGDA VMYASTECKA EVTPSQDGNR
60 70 80 90 100
TFSYTLEDHT KQAFGIMNEL RLSQQLCDVT LQVKYEDIPA AQFMAHKVVL
110 120 130 140 150
ASSSPVFKAM FTNGLREQGM EVVSIEGIHP KVMERLIEFA YTASISVGEK
160 170 180 190 200
CVLHVMNGAV MYQIDSVVRA CSDFLVQQLD PSNAIGIANF AEQIGCTELH
210 220 230 240 250
QRAREYIYMH FGEEEFFNLS HCQLATLISR DDLNVRCESE VFHACIDWVK
260 270 280 290 300
YDCPQRRFYV QALLRAVRCH ALTPRFLQTQ LQKCEILQAD ARCKDYLVQI
310 320 330 340 350
FQELTLHKPT QAVPCRAPKV GRLIYTAGGY FRQSLSYLEA YNPSNGSWLR
360 370 380 390 400
LADLQVPRSG LAGCVVGGLL YAVGGRNNSP DGNTDSSALD CYNPMTNQWS
410 420 430 440 450
PCASMSVPRN RIGVGVIDGH IYAVGGSHGC IHHSSVERYE PDRDEWHLVA
460 470 480 490 500
PMLTRRIGVG VAVLNRLLYA VGGFDGTNRL NSAECYYPER NEWRMITPMN
510 520 530 540 550
TIRSGAGVCV LHSCIYAAGG YDGQDQLNSV ERYDVETETW TFVASMKHRR
560 570 580 590 600
SALGIAVHQG RIYVLGGYDG HTFLDSVECY DPDTDTWSEV TRLTSGRSGV
610 620
GVAVTMEPCR KQIDQQNCTC
Length:620
Mass (Da):69,058
Last modified:July 22, 2015 - v2
Checksum:i2B8E82FC516C9F02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07069441 Genomic DNA. No translation available.
AABR07069442 Genomic DNA. No translation available.
RefSeqiNP_476493.2. NM_057152.2.
UniGeneiRn.23467.

Genome annotation databases

EnsembliENSRNOT00000028360; ENSRNOP00000028360; ENSRNOG00000020878.
GeneIDi117519.
KEGGirno:117519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07069441 Genomic DNA. No translation available.
AABR07069442 Genomic DNA. No translation available.
RefSeqiNP_476493.2. NM_057152.2.
UniGeneiRn.23467.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028360.

Proteomic databases

PaxDbiG3V8U2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028360; ENSRNOP00000028360; ENSRNOG00000020878.
GeneIDi117519.
KEGGirno:117519.

Organism-specific databases

CTDi9817.
RGDi621619. Keap1.

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
GeneTreeiENSGT00760000118931.
KOiK10456.
OMAiRSHGMLT.
OrthoDBiEOG091G02T3.
TreeFamiTF329218.

Gene expression databases

BgeeiENSRNOG00000020878.

Family and domain databases

Gene3Di2.130.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR015916. Gal_Oxidase_b-propeller.
IPR030563. KEAP1.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PANTHERiPTHR24412:SF162. PTHR24412:SF162. 1 hit.
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 6 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG3V8U2_RAT
AccessioniPrimary (citable) accession number: G3V8U2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: July 22, 2015
Last modified: September 7, 2016
This is version 37 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.