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G3V846

- G3V846_RAT

UniProt

G3V846 - G3V846_RAT

Protein
Submitted name:

Excitatory amino acid transporter 1

Gene

Slc1a3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. glutamate binding Source: Ensembl
    2. high-affinity glutamate transmembrane transporter activity Source: Ensembl
    3. sodium:dicarboxylate symporter activity Source: InterPro

    GO - Biological processi

    1. auditory behavior Source: Ensembl
    2. cell morphogenesis involved in neuron differentiation Source: Ensembl
    3. cranial nerve development Source: Ensembl
    4. D-aspartate import Source: Ensembl
    5. gamma-aminobutyric acid biosynthetic process Source: Ensembl
    6. glutamate biosynthetic process Source: Ensembl
    7. L-glutamate import Source: Ensembl
    8. neuromuscular process controlling balance Source: Ensembl
    9. positive regulation of synaptic transmission Source: Ensembl
    10. response to antibiotic Source: Ensembl
    11. response to drug Source: Ensembl
    12. response to light stimulus Source: Ensembl
    13. response to wounding Source: Ensembl
    14. sensory perception of sound Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Excitatory amino acid transporter 1Imported
    Submitted name:
    Solute carrier family 1 (Glial high affinity glutamate transporter), member 3, isoform CRA_aImported
    Gene namesi
    Name:Slc1a3Imported
    ORF Names:rCG_50959Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 2

    Organism-specific databases

    RGDi3698. Slc1a3.

    Subcellular locationi

    GO - Cellular componenti

    1. cell projection Source: Ensembl
    2. cell surface Source: Ensembl
    3. fibril Source: Ensembl
    4. neuronal cell body Source: Ensembl
    5. plasma membrane Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000110358.
    KOiK05614.
    OMAiTLRPYRM.
    OrthoDBiEOG7RV9G2.
    TreeFamiTF315206.

    Family and domain databases

    Gene3Di1.10.3860.10. 2 hits.
    InterProiIPR001991. Na-dicarboxylate_symporter.
    IPR018107. Na-dicarboxylate_symporter_CS.
    [Graphical view]
    PANTHERiPTHR11958. PTHR11958. 1 hit.
    PfamiPF00375. SDF. 1 hit.
    [Graphical view]
    PRINTSiPR00173. EDTRNSPORT.
    SUPFAMiSSF118215. SSF118215. 2 hits.
    PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
    PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3V846-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKSNGEEPR MGSRMERFQQ GVRKRTLLAK KKVQNITKED VKSYLFRNAF    50
    VLLTVSAVIV GTILGFALRP YKMSYREVKY FSFPGELLMR MLQMLVLPLI 100
    ISSLVTGMAA LDSKASGKMG MRAVVYYMTT TIIAVVIGII IVIIIHPGKG 150
    TKENMYREGK IVQVTAADAF LDLIRNMFPP NLVEACFKQF KTSYEKRSFK 200
    VPIQANETLL GAVINNVSEA METLTRIREE MVPVPGSVNG VNALGLVVFS 250
    MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP LGILFLIAGK 300
    IVEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG 350
    GLLQALITAL GTSSSSATLP ITFKCLEENN GVDKRITRFV LPVGATINMD 400
    GTALYEALAA IFIAQVNNFD LNFGQIITIS ITATAASIGA AGIPQAGLVT 450
    MVIVLTSVGL PTDDITLIIA VDWFLDRLRT TTNVLGDSLG AGIVEHLSRH 500
    ELKNRDVEMG NSVIEENEMK KPYQLIAQDN EPEKPVADSE TKM 543
    Length:543
    Mass (Da):59,683
    Last modified:November 16, 2011 - v1
    Checksum:iAB05E53CBB4BE090
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06013425 Genomic DNA. No translation available.
    AABR06013426 Genomic DNA. No translation available.
    CH474048 Genomic DNA. Translation: EDL75679.1.
    RefSeqiNP_062098.1. NM_019225.2.
    UniGeneiRn.34134.

    Genome annotation databases

    EnsembliENSRNOT00000022319; ENSRNOP00000022319; ENSRNOG00000016163.
    GeneIDi29483.
    KEGGirno:29483.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06013425 Genomic DNA. No translation available.
    AABR06013426 Genomic DNA. No translation available.
    CH474048 Genomic DNA. Translation: EDL75679.1 .
    RefSeqi NP_062098.1. NM_019225.2.
    UniGenei Rn.34134.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000022319 ; ENSRNOP00000022319 ; ENSRNOG00000016163 .
    GeneIDi 29483.
    KEGGi rno:29483.

    Organism-specific databases

    CTDi 6507.
    RGDi 3698. Slc1a3.

    Phylogenomic databases

    GeneTreei ENSGT00730000110358.
    KOi K05614.
    OMAi TLRPYRM.
    OrthoDBi EOG7RV9G2.
    TreeFami TF315206.

    Miscellaneous databases

    NextBioi 609342.
    PROi G3V846.

    Family and domain databases

    Gene3Di 1.10.3860.10. 2 hits.
    InterProi IPR001991. Na-dicarboxylate_symporter.
    IPR018107. Na-dicarboxylate_symporter_CS.
    [Graphical view ]
    PANTHERi PTHR11958. PTHR11958. 1 hit.
    Pfami PF00375. SDF. 1 hit.
    [Graphical view ]
    PRINTSi PR00173. EDTRNSPORT.
    SUPFAMi SSF118215. SSF118215. 2 hits.
    PROSITEi PS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
    PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiG3V846_RAT
    AccessioniPrimary (citable) accession number: G3V846
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3