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Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei315UniRule annotation1
Active sitei374UniRule annotation1
Active sitei397UniRule annotation1
Metal bindingi437CalciumUniRule annotation1
Metal bindingi439CalciumUniRule annotation1
Metal bindingi486CalciumUniRule annotation1
Metal bindingi491CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-114608 Platelet degranulation
R-RNO-140875 Common Pathway of Fibrin Clot Formation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Submitted name:
Coagulation factor XIII, A1 subunit, isoform CRA_aImported
Gene namesi
Name:F13a1Imported
ORF Names:rCG_44203Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 17

Organism-specific databases

RGDi621495 F13a1

PTM / Processingi

Proteomic databases

PRIDEiG3V811

Expressioni

Gene expression databases

BgeeiENSRNOG00000015957

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini307 – 400TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
KOiK03917
OMAiCEEDAVY
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR034810 Factor_XIII_A
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PANTHERiPTHR11590:SF42 PTHR11590:SF42, 1 hit
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

G3V811-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTPATTFG GRRAIPPNNS NAAEVDLPTE DLQGLVPRGV SLKDYLNVTA
60 70 80 90 100
VHLFKERWDS NKIDHHTDKY DNNKLIVRRG QTFYIQIDFN RPYDPRKDLF
110 120 130 140 150
RVEYVIGRYP QENKGTYIPV PVVTELQSGK WGAKVIMNED RSVRLSVQSS
160 170 180 190 200
PECIVGKFRM YVAVWTPYGI LRTQRDPETD TYILFNPWCE EDAVYLDDEK
210 220 230 240 250
EREEYVLNDI GVIFHGDFND IKSRSWSYGQ FEDGILDACL YVMDKAEMDL
260 270 280 290 300
SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNVYAYGIPP SAWTGSVDIL
310 320 330 340 350
LEYRSSETPV RYGQCWVFAG VFNTFLRCLG IPARVITNYF SAHDNDANLQ
360 370 380 390 400
MDIFLEEDGS VSSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP
410 420 430 440 450
QENSDGMYRC GPASVQAVKH GHVCFQFDAP FVFAEVNSDL VYITAKKDGT
460 470 480 490 500
HVVENVDATH IGKLIVTKEI GGDGMQDITD TYKFQEGQEE ERLALETALM
510 520 530 540 550
YGAKKTLNTE GVVKSRSDVD MNFDVENAVL GKDFRVTITF QNNSSNLYTI
560 570 580 590 600
LAYLSGNITF YTGVSKKEFK TESFEVTLDP LSLEKKEVLI RAGEYMSYLL
610 620 630 640 650
EQGLLHFFVT ARINETRVVL AKQKSIVLTI PKVTIKVRGT AMVGSDMVVT
660 670 680 690 700
VEFTNPLKET LKNVWLHLEG PGVMRPKRKM FREIRPNATV QWEEVCQPWV
710 720 730
SGHRKLIASM TSDSLRHVYG ELDLQIRRRP TV
Length:732
Mass (Da):83,054
Last modified:November 16, 2011 - v1
Checksum:i0521B647C6B6D4CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07027401 Genomic DNA No translation available.
AABR07027402 Genomic DNA No translation available.
CH473977 Genomic DNA Translation: EDL98278.1
CH473977 Genomic DNA Translation: EDL98279.1
RefSeqiNP_067730.2, NM_021698.2
UniGeneiRn.42925

Genome annotation databases

EnsembliENSRNOT00000021568; ENSRNOP00000021568; ENSRNOG00000015957
GeneIDi60327
KEGGirno:60327

Similar proteinsi

Entry informationi

Entry nameiG3V811_RAT
AccessioniPrimary (citable) accession number: G3V811
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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