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G3V7L3 (G3V7L3_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

RCG29725, isoform CRA_b EMBL EDM01952.1
Gene names
Name:C1s Ensembl ENSRNOP00000016330 RGD 619983
ORF Names:rCG_29725 EMBL EDM01952.1
OrganismRattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000016330
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length694 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Contains peptidase S1 domain. SAAS SAAS018097

Contains peptidase Sdomain. SAAS SAAS018097

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site4811Charge relay system By similarity
Active site5351Charge relay system By similarity
Active site6371Charge relay system By similarity PIRSR PIRSR001155-1

Amino acid modifications

Disulfide bond71 ↔ 89 By similarity PIRSR PIRSR001155-2
Disulfide bond149 ↔ 162 By similarity PIRSR PIRSR001155-2
Disulfide bond164 ↔ 177 By similarity PIRSR PIRSR001155-2
Disulfide bond181 ↔ 208 By similarity PIRSR PIRSR001155-2
Disulfide bond327 ↔ 360 By similarity PIRSR PIRSR001155-2

Sequences

Sequence LengthMass (Da)Tools
G3V7L3 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 455A9EE10C8CC12F

FASTA69477,713
        10         20         30         40         50         60 
MGKSPEMWCF VFFSLLASFS AEPTMYGEIL SPNYPQAYPN EVVKTWDIEV PEGFGIHLYF 

        70         80         90        100        110        120 
THLDMELSEN CAYDSVQIIS GGIEEERLCG QRTSKSPNSP IVEEFQFPYN RLQVVFTSDF 

       130        140        150        160        170        180 
SNEERFTGFA AYYSAVDVNE CTDFTDVPCS HFCNNFIGGY FCSCPPEYFL HDDMRTCGVN 

       190        200        210        220        230        240 
CSGDVFTALI GEIASPNYPN PYPENSRCEY QIRLQEGFRL VLTIRREDFD VEPADSEGNC 

       250        260        270        280        290        300 
HDSLTFAAKN QQFGPYCGNG FPGPLTIKTQ SNTLDIVFQT DLTGQNKGWK LRYHGDPIPC 

       310        320        330        340        350        360 
PKEISANSIW EPEKAKYVFK DVVKITCVDG FEVVEGNVGS TSFYSTCQSN GQWSNSRLEC 

       370        380        390        400        410        420 
QPVDCGVPEP IENGKVEDPE DTVFGSVIHY TCEEPYYYME QEEGGEYHCA ANGSWVNDQL 

       430        440        450        460        470        480 
GVELPKCIPV CGVPTEPFKV QQRIFGGYST KIQSFPWQVY FESPRGGGAL IDEYWVLTAA 

       490        500        510        520        530        540 
HVVEGNSDPV MYVGSTLLKI ERLRNAQRLI TERVIIHPSW KQEDDLNTRT NFDNDIALVQ 

       550        560        570        580        590        600 
LKDPVKMGPT VAPICLPETS SDYNPSEGDL GLISGWGRTE NRTNVIQLRG AKLPITSLEK 

       610        620        630        640        650        660 
CQQVKVENPK ARSNDYVFTD NMICAGEKGV DSCEGDSGGA FALPVPNVKD PKFYVAGLVS 

       670        680        690 
WGKKCGTYGI YTKVKNYVDW ILKTMQENSG PKKD 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000016330.
[2]"Gene and alternative splicing annotation with AIR."
Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G.
Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDM01952.1.
[3]Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. expand/collapse author list , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDM01952.1.
[4]Ensembl
Submitted (SEP-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000016330.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06033512 Genomic DNA. No translation available.
CH473964 Genomic DNA. Translation: EDM01952.1.

3D structure databases

ProteinModelPortalG3V7L3.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSS01.193.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000016330; ENSRNOP00000016330; ENSRNOG00000011971.

Organism-specific databases

RGD619983. C1s.

Phylogenomic databases

GeneTreeENSGT00560000076882.
OMAPTMYGEI.
OrthoDBEOG7W6WK4.
TreeFamTF330373.

Family and domain databases

Gene3D2.60.120.290. 2 hits.
InterProIPR000859. CUB_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR024175. Pept_S1A_C1r/C1S/mannan-bd.
IPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR000436. Sushi_SCR_CCP.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamPF00431. CUB. 2 hits.
PF00084. Sushi. 2 hits.
PF00089. Trypsin. 1 hit.
[Graphical view]
PIRSFPIRSF001155. C1r_C1s_MASP. 1 hit.
PRINTSPR00722. CHYMOTRYPSIN.
SMARTSM00032. CCP. 2 hits.
SM00042. CUB. 2 hits.
SM00179. EGF_CA. 1 hit.
SM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMSSF49854. SSF49854. 2 hits.
SSF50494. SSF50494. 1 hit.
SSF57535. SSF57535. 2 hits.
PROSITEPS00010. ASX_HYDROXYL. 1 hit.
PS01180. CUB. 2 hits.
PS01187. EGF_CA. 1 hit.
PS50923. SUSHI. 2 hits.
PS50240. TRYPSIN_DOM. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35583970.

Entry information

Entry nameG3V7L3_RAT
AccessionPrimary (citable) accession number: G3V7L3
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)