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G3V7K7

- G3V7K7_RAT

UniProt

G3V7K7 - G3V7K7_RAT

Protein
Submitted name:

Cell adhesion molecule-related/down-regulated by oncogenes

Gene

Cdon

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. anterior/posterior pattern specification Source: Ensembl
    2. cell fate specification Source: Ensembl
    3. cerebral cortex development Source: Ensembl
    4. embryonic body morphogenesis Source: Ensembl
    5. embryonic retina morphogenesis in camera-type eye Source: Ensembl
    6. lens development in camera-type eye Source: Ensembl
    7. myoblast fusion Source: Ensembl
    8. positive regulation of MAPK cascade Source: Ensembl
    9. positive regulation of neural precursor cell proliferation Source: Ensembl
    10. positive regulation of neuron differentiation Source: Ensembl
    11. positive regulation of protein phosphorylation Source: Ensembl
    12. positive regulation of skeletal muscle tissue development Source: Ensembl
    13. positive regulation of small GTPase mediated signal transduction Source: Ensembl
    14. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    15. regulation of protein heterodimerization activity Source: Ensembl
    16. skeletal muscle satellite cell differentiation Source: Ensembl
    17. smoothened signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cell adhesion molecule-related/down-regulated by oncogenesImported
    Gene namesi
    Name:CdonImported
    ORF Names:rCG_22740Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 8

    Organism-specific databases

    RGDi708433. Cdon.

    Family & Domainsi

    Keywords - Domaini

    RepeatSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117685.
    OMAiVSDTQIM.
    OrthoDBiEOG7MD4PB.
    TreeFamiTF332268.

    Family and domain databases

    Gene3Di2.60.40.10. 8 hits.
    InterProiIPR003961. Fibronectin_type3.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    [Graphical view]
    PfamiPF00041. fn3. 3 hits.
    PF07679. I-set. 3 hits.
    [Graphical view]
    SMARTiSM00060. FN3. 3 hits.
    SM00409. IG. 1 hit.
    SM00408. IGc2. 4 hits.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 2 hits.
    PROSITEiPS50853. FN3. 4 hits.
    PS50835. IG_LIKE. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3V7K7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHPDLGPLWK LLYVLVILCS SVSSDLAPYF ISEPLSAVQK LGRPVVLHCS     50
    AKPVTARISW LHNGKRLDRN TEQIKIHRGT LTILSLNPSL SGCYQCVANN 100
    SVGAVVSGPA TVSAAALADF DSSTMHVITA EEKNTGFIGC RVPESNPKAE 150
    VRYKIRGKWL MYSTGNYIIL PSGNLQILNV SSKDKGSYKC AAYNPVTSEL 200
    KVEPAGRKLL VSRPSSDGFH ILHPALSQAL AVLPHSPVTL ECVVSGVPAS 250
    QVYWLKDGQD ALSGSNWRRL YSHLATASID PADSGNYSCV VGNNRSGDVK 300
    HVTYTVNVLE HASISKGLHD QKVSLGATVR FTCEVHGNPA PNRTWFHNAQ 350
    PIRPSSRHLT EGSVLKITGV IMEDSGLYQC MADNGIGFMQ STGRLQIEQD 400
    SGQRPVIVTA PANVEVTDGD FVTLSCNATG EPVPVIHWYG RHGLITSHPS 450
    QVLRSKSRKS HLFRPGDLDP EPVYLIMSQA GSSSLSIQAV TWEHAGKYTC 500
    EAVNKHGSTQ SEAFLTVVPF ETNTKAEPVT PSEASQNDER DPRDGSESGL 550
    LNLFPVKVHS GGVELPAEKN ASVPDAPNIL SPPQTHMPDT YTLVWRAGRD 600
    GGMPINAYFV KYRKLDDGSG AVGSWHTVRV PGSESELHLT ELEPSSLYEV 650
    LMVARSAVGE GQPAMLTFRT SKEKMASSKN TQASFPPVGI PKRPVTSEAS 700
    NSNFGVVLTD SSRHSGVPEA PDRPTISMAS ETSVYVTWIP RANGGSPITA 750
    FKVEYKRMKS SDWLVAAEDI PPSKLSVEVR SLEPGSIYKF RVIAINHYGE 800
    SFRSSASRPY QVAGFPNRFS NRPITGPHIA YTEAVSDTQI MLKWTYIPSS 850
    NNNTPIQGFY IYYRPTDSDN DSDYKRDVVE GSKQWHTIGH LQPETSYDIK 900
    MQCFNEGGES EFSNVMICET KVKRVPGASE YPMKELSTPP SSSGNGGNVG 950
    PATSPARSSD MLYLIVGCVL GVMVLILLVF IALCLWKSRQ QSAIQKYDPP 1000
    GYLYQGSEIN GQMVEYTTLS GTARINGSVH GGFLSKGSLS NGCSHLHHKG 1050
    PNGVNGILNG TINGGLYSAH TSSLTRTCVE FEHPHHLVNG GAVYTAVPQM 1100
    DPLECINCRN CRNNNRCFTK TNSPLPVVPV VASYPQDGLE MKPLGVMKFP 1150
    VCPVSTVPDG GQIPEECLKD SVAPAPTQRT CRQDNTSDIN SDSTEDTAEF 1200
    NRGDSSGHSE AEDKVFSWSP LILSPVLEDC SEKTAWSPPG PPLDGLSVVL 1250
    QQAQET 1256
    Length:1,256
    Mass (Da):136,166
    Last modified:November 16, 2011 - v1
    Checksum:i02981D8A4119B338
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06054065 Genomic DNA. No translation available.
    CH474007 Genomic DNA. Translation: EDL83270.1.
    RefSeqiXP_006242853.1. XM_006242791.1.
    XP_006242854.1. XM_006242792.1.
    UniGeneiRn.10818.

    Genome annotation databases

    EnsembliENSRNOT00000016248; ENSRNOP00000016247; ENSRNOG00000011789.
    GeneIDi50938.
    KEGGirno:50938.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06054065 Genomic DNA. No translation available.
    CH474007 Genomic DNA. Translation: EDL83270.1 .
    RefSeqi XP_006242853.1. XM_006242791.1.
    XP_006242854.1. XM_006242792.1.
    UniGenei Rn.10818.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000016248 ; ENSRNOP00000016247 ; ENSRNOG00000011789 .
    GeneIDi 50938.
    KEGGi rno:50938.

    Organism-specific databases

    CTDi 50937.
    RGDi 708433. Cdon.

    Phylogenomic databases

    GeneTreei ENSGT00750000117685.
    OMAi VSDTQIM.
    OrthoDBi EOG7MD4PB.
    TreeFami TF332268.

    Miscellaneous databases

    NextBioi 35583965.
    PROi G3V7K7.

    Family and domain databases

    Gene3Di 2.60.40.10. 8 hits.
    InterProi IPR003961. Fibronectin_type3.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    [Graphical view ]
    Pfami PF00041. fn3. 3 hits.
    PF07679. I-set. 3 hits.
    [Graphical view ]
    SMARTi SM00060. FN3. 3 hits.
    SM00409. IG. 1 hit.
    SM00408. IGc2. 4 hits.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 2 hits.
    PROSITEi PS50853. FN3. 4 hits.
    PS50835. IG_LIKE. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiG3V7K7_RAT
    AccessioniPrimary (citable) accession number: G3V7K7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3