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Protein
Submitted name:

Cell adhesion molecule-related/down-regulated by oncogenes

Gene

Cdon

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-375170 CDO in myogenesis
R-RNO-5632681 Ligand-receptor interactions
R-RNO-5635838 Activation of SMO

Names & Taxonomyi

Protein namesi
Submitted name:
Cell adhesion molecule-related/down-regulated by oncogenesImported
Gene namesi
Name:CdonImported
ORF Names:rCG_22740Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi708433 Cdon

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei961 – 986HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501509175025 – 1256Sequence analysisAdd BLAST1232

Expressioni

Gene expression databases

BgeeiENSRNOG00000011789

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 113Ig-likeInterPro annotationAdd BLAST86
Domaini224 – 305Ig-likeInterPro annotationAdd BLAST82
Domaini310 – 396Ig-likeInterPro annotationAdd BLAST87
Domaini405 – 516Ig-likeInterPro annotationAdd BLAST112
Domaini573 – 674Fibronectin type-IIIInterPro annotationAdd BLAST102
Domaini720 – 815Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini823 – 923Fibronectin type-IIIInterPro annotationAdd BLAST101

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHIH Eukaryota
ENOG410XSVT LUCA
GeneTreeiENSGT00910000144011
OMAiTWIPRAN
OrthoDBiEOG091G00TB
TreeFamiTF332268

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 8 hits
InterProiView protein in InterPro
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PANTHERiPTHR44170:SF1 PTHR44170:SF1, 1 hit
PfamiView protein in Pfam
PF00041 fn3, 3 hits
PF07679 I-set, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SUPFAMiSSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 4 hits

Sequencei

Sequence statusi: Complete.

G3V7K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDLGPLWK LLYVLVILCS SVSSDLAPYF ISEPLSAVQK LGRPVVLHCS
60 70 80 90 100
AKPVTARISW LHNGKRLDRN TEQIKIHRGT LTILSLNPSL SGCYQCVANN
110 120 130 140 150
SVGAVVSGPA TVSAAALADF DSSTMHVITA EEKNTGFIGC RVPESNPKAE
160 170 180 190 200
VRYKIRGKWL MYSTGNYIIL PSGNLQILNV SSKDKGSYKC AAYNPVTSEL
210 220 230 240 250
KVEPAGRKLL VSRPSSDGFH ILHPALSQAL AVLPHSPVTL ECVVSGVPAS
260 270 280 290 300
QVYWLKDGQD ALSGSNWRRL YSHLATASID PADSGNYSCV VGNNRSGDVK
310 320 330 340 350
HVTYTVNVLE HASISKGLHD QKVSLGATVR FTCEVHGNPA PNRTWFHNAQ
360 370 380 390 400
PIRPSSRHLT EGSVLKITGV IMEDSGLYQC MADNGIGFMQ STGRLQIEQD
410 420 430 440 450
SGQRPVIVTA PANVEVTDGD FVTLSCNATG EPVPVIHWYG RHGLITSHPS
460 470 480 490 500
QVLRSKSRKS HLFRPGDLDP EPVYLIMSQA GSSSLSIQAV TWEHAGKYTC
510 520 530 540 550
EAVNKHGSTQ SEAFLTVVPF ETNTKAEPVT PSEASQNDER DPRDGSESGL
560 570 580 590 600
LNLFPVKVHS GGVELPAEKN ASVPDAPNIL SPPQTHMPDT YTLVWRAGRD
610 620 630 640 650
GGMPINAYFV KYRKLDDGSG AVGSWHTVRV PGSESELHLT ELEPSSLYEV
660 670 680 690 700
LMVARSAVGE GQPAMLTFRT SKEKMASSKN TQASFPPVGI PKRPVTSEAS
710 720 730 740 750
NSNFGVVLTD SSRHSGVPEA PDRPTISMAS ETSVYVTWIP RANGGSPITA
760 770 780 790 800
FKVEYKRMKS SDWLVAAEDI PPSKLSVEVR SLEPGSIYKF RVIAINHYGE
810 820 830 840 850
SFRSSASRPY QVAGFPNRFS NRPITGPHIA YTEAVSDTQI MLKWTYIPSS
860 870 880 890 900
NNNTPIQGFY IYYRPTDSDN DSDYKRDVVE GSKQWHTIGH LQPETSYDIK
910 920 930 940 950
MQCFNEGGES EFSNVMICET KVKRVPGASE YPMKELSTPP SSSGNGGNVG
960 970 980 990 1000
PATSPARSSD MLYLIVGCVL GVMVLILLVF IALCLWKSRQ QSAIQKYDPP
1010 1020 1030 1040 1050
GYLYQGSEIN GQMVEYTTLS GTARINGSVH GGFLSKGSLS NGCSHLHHKG
1060 1070 1080 1090 1100
PNGVNGILNG TINGGLYSAH TSSLTRTCVE FEHPHHLVNG GAVYTAVPQM
1110 1120 1130 1140 1150
DPLECINCRN CRNNNRCFTK TNSPLPVVPV VASYPQDGLE MKPLGVMKFP
1160 1170 1180 1190 1200
VCPVSTVPDG GQIPEECLKD SVAPAPTQRT CRQDNTSDIN SDSTEDTAEF
1210 1220 1230 1240 1250
NRGDSSGHSE AEDKVFSWSP LILSPVLEDC SEKTAWSPPG PPLDGLSVVL

QQAQET
Length:1,256
Mass (Da):136,166
Last modified:November 16, 2011 - v1
Checksum:i02981D8A4119B338
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132671 Genomic DNA No translation available.
CH474007 Genomic DNA Translation: EDL83270.1
RefSeqiXP_006242853.1, XM_006242791.3
XP_006242854.1, XM_006242792.3
UniGeneiRn.10818

Genome annotation databases

EnsembliENSRNOT00000016248; ENSRNOP00000016247; ENSRNOG00000011789
GeneIDi50938

Similar proteinsi

Entry informationi

Entry nameiG3V7K7_RAT
AccessioniPrimary (citable) accession number: G3V7K7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 20, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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