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Protein
Submitted name:

Hairless homolog (Mouse), isoform CRA_b

Gene

Hr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. transcription corepressor activity Source: Ensembl

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Hairless homolog (Mouse), isoform CRA_bImported
Submitted name:
Lysine-specific demethylase hairlessImported
Gene namesi
Name:HrImported
Synonyms:hrImported
ORF Names:rCG_36905Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 15

Organism-specific databases

RGDi620634. Hr.

Subcellular locationi

GO - Cellular componenti

  1. nuclear body Source: Ensembl
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Contains JmjC domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00530000063039.
OMAiSTAVKLC.
OrthoDBiEOG7PZRWJ.
TreeFamiTF324723.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3V7J4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLRSSCFVL TLQDPPLGEP HEGRRVMESM PSFLKDTPAW EKTAPVNGIV
60 70 80 90 100
GQEPGTSPQD GLHHGALCLG EPVPFWRGVL SAPDSWLPPG FLQGPKDTLS
110 120 130 140 150
VVEGEGSRNG ERKANWLGSK EGLRWKEAML AHPLAFCGPA CPPRYGPLIP
160 170 180 190 200
EHSSGHPKSD PVAFRPLHCP FLLETKILER APFWVPTCLP PYLMSSLPPE
210 220 230 240 250
RSYDWPLAPS PWVYSGSQPK VPSAFSLGSK GFYHKDPNIL RPAKEPLAAS
260 270 280 290 300
ESGMLGLAPG GHLQQACDAE GPSLHQRDGE TGAGRQQNLC PVFLGYPDTV
310 320 330 340 350
PRTPWPSCPP GLVHTLGNVW AGPGSNSFGY QLGPPVTPRC PSPGPPTPPG
360 370 380 390 400
GCCSSHLPAR EGDPGPCRKC QDSPEGSSSG PGESSEERNK AGSRASPPSH
410 420 430 440 450
HTKLKKTWLT RHSEQFECPG GCPGKGESPA TGLRALKRAG SPEVQGARGP
460 470 480 490 500
APKRPSHTFP GTGRQGARAW QETPETSTGS KAEAQQQEEQ RGPRDGRIRL
510 520 530 540 550
RESRLEDTSC QHHLAGVTQC PSCVQAAGEV EILTSHSQKS HRLPLEEKPL
560 570 580 590 600
EEDSCATSEE GGGSSPEASI NKGLAKHLLS GLGDRLCRLL RKEREALAWA
610 620 630 640 650
QREGQGPAMT EDSPGIPHCC SRCHHGLFNT HWRCSHCSHR LCVACGRIAG
660 670 680 690 700
AGKNREKTGS REQRTDDCAQ EAGHAACSLI LTQFVSSQAL AELSTVMHQV
710 720 730 740 750
WAKFDIRGHC FCQVDARVWA PGDGGQQKEP TEKTPPAPQL SCNGDSNRTK
760 770 780 790 800
DIKEETPDST ESPAEDRAGR SPLPCPSLCE LLASTAVKLC LGHERIHMAF
810 820 830 840 850
APVTPALPSD DRITNILDSI IAQVVERKIQ EKALGPGLRA GSGLRKGLSL
860 870 880 890 900
PLSPVRTRLS PPGALLWLQE PRPKHGFRLF QEHWRQGQPV LVSGIQKTLR
910 920 930 940 950
LSLWGMEALG TLGGQVQTLT ALGPPQPTSL DSTAFWKGFS HPEARPKLDE
960 970 980 990 1000
GSVLLLHRPL GDKDESRVEN LASSLPLPEY CAHQGKLNLA SYLPLGLTLH
1010 1020 1030 1040 1050
PLEPQLWAAY GVNSHRGHLG TKNLCVEVSD LISILVHAEA QLPPWYRAQK
1060 1070 1080 1090 1100
DFLSGLDGEG LWSPGSQTST VWHVFRAQDA QRIRRFLQMV CPAGAGTLEP
1110 1120 1130 1140 1150
GAPGSCYLDS GLRRRLREEW GVSCWTLLQA PGEAVLVPAG APHQVQGLVS
1160 1170 1180 1190 1200
TISVTQHFLS PETSALSAQL CHQGASLPPD HRMLYAQMDR AVFQAVKVAV

GTLQEAK
Length:1,207
Mass (Da):130,241
Last modified:November 16, 2011 - v1
Checksum:i228AD7EE8C25AFE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06083962 Genomic DNA. No translation available.
CH473951 Genomic DNA. Translation: EDM02230.1.
RefSeqiXP_006252345.1. XM_006252283.1.
XP_008769055.1. XM_008770833.1.
UniGeneiRn.41543.

Genome annotation databases

EnsembliENSRNOT00000015716; ENSRNOP00000015716; ENSRNOG00000011427.
GeneIDi60563.
KEGGirno:60563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06083962 Genomic DNA. No translation available.
CH473951 Genomic DNA. Translation: EDM02230.1.
RefSeqiXP_006252345.1. XM_006252283.1.
XP_008769055.1. XM_008770833.1.
UniGeneiRn.41543.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000015716; ENSRNOP00000015716; ENSRNOG00000011427.
GeneIDi60563.
KEGGirno:60563.

Organism-specific databases

CTDi55806.
RGDi620634. Hr.

Phylogenomic databases

GeneTreeiENSGT00530000063039.
OMAiSTAVKLC.
OrthoDBiEOG7PZRWJ.
TreeFamiTF324723.

Miscellaneous databases

NextBioi612242.
PROiG3V7J4.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiG3V7J4_RAT
AccessioniPrimary (citable) accession number: G3V7J4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.