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Protein

Cation-transporting ATPase

Gene

Atp13a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-936837. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Cation-transporting ATPaseUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:Atp13a1Imported
Synonyms:Atp13a1_predictedImported
ORF Names:rCG_38664Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1306033. Atp13a1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei61 – 84HelicalUniRule annotationAdd BLAST24
Transmembranei90 – 110HelicalUniRule annotationAdd BLAST21
Transmembranei439 – 458HelicalUniRule annotationAdd BLAST20
Transmembranei1045 – 1066HelicalUniRule annotationAdd BLAST22
Transmembranei1096 – 1114HelicalUniRule annotationAdd BLAST19
Transmembranei1126 – 1144HelicalUniRule annotationAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000010776.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015247.

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG0209. Eukaryota.
COG0474. LUCA.
GeneTreeiENSGT00550000075064.
KOiK14950.
OMAiQVSTFAI.
OrthoDBiEOG091G00UD.
TreeFamiTF300725.

Family and domain databases

Gene3Di3.40.1110.10. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_dom_N.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR036412. HAD-like_sf.
IPR006544. P-type_TPase_V.
IPR001757. P_typ_ATPase.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 1 hit.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3V7I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVVGNAVPC GARPGGARGS GSPQPGRPGL AAGPALIASG DELVAAVWPY
60 70 80 90 100
RRLALLRRLT VLPFAGLLYP AWLGAAASGC WGWGNSWTQI PEAALLALAT
110 120 130 140 150
ICLAHALTIL SGHWSVHAHC ALTCTPEHDP NKVTFVKVVP TPNNGSTELV
160 170 180 190 200
ALHRDKGEDG LEVLSFEFQK IKYSYDALEK KQFLPVAFPV GNAFSYYQSN
210 220 230 240 250
RGFQEDSDIR AAEKKFGSNK AEMAVPDFSE LFKERATAPF FVFQVFCVGL
260 270 280 290 300
WCLDEYWYYS VFTLSMLVAF EASLVQQQMR NMSEIRKMGN KPHMIQVYRS
310 320 330 340 350
RKWRPIASDD IVPGDIVSIG RSPQENLVPC DVLLLRGRCI VDEAMLTGES
360 370 380 390 400
VPQMKEPIED LSPDRVLDLQ ADARLHVIFG GTKVVQHIPP QKATSGLKPV
410 420 430 440 450
DNGCVAFVLR TGFNTSQGKL LRTILFGVKR VTANNLETFI FILFLLVFAI
460 470 480 490 500
AAAAYVWIEG TKDPSRNRYK LFLECTLILT SVVPPELPIE LSLAVNTSLI
510 520 530 540 550
ALAKLYMYCT EPFRIPFAGK VEVCCFDKTG TLTSDSLVVR GVAGLRDGKE
560 570 580 590 600
VTPVSSIPIE THRALASCHS LMQLDDGTLV GDPLEKAMLT AVDWTLTKDE
610 620 630 640 650
KVFPRSIKTQ GLKIHQRFHF ASALKRMSVL ASYEKLGSTD LCYIAAVKGA
660 670 680 690 700
PETLHSMFSQ CPPDYHHIHT EISREGARVL ALGYKELGHL THQQAREVKR
710 720 730 740 750
EALECSLKFV GFIVVSCPLK ADSKAVIREI QNASHRVVMI TGDNPLTACH
760 770 780 790 800
VAQELHFIDK AHTLILHPPS EKGQPCEWRS IDNSIVLPLT LGSPKALALE
810 820 830 840 850
HALCLTGDGL AHLQAVDPQQ LLHLIPHVQV FARVAPKQKE FVITSLKELG
860 870 880 890 900
YVTLMCGDGT NDVGALKHAD VGVALLANAP ERVVERRRRP RDSPVLSNSG
910 920 930 940 950
PRVSRSTKQK SALLSPEEPP ASHRDRLSQV LRDLEDESTP IVKLGDASIA
960 970 980 990 1000
APFTSKLSSI QCICHVIKQG RCTLVTTLQM FKILALNALI LAYSQSVLYL
1010 1020 1030 1040 1050
EGVKFSDFQA TLQGLLLAGC FLFISRSKPL KTLSRERPLP NIFNLYTILT
1060 1070 1080 1090 1100
VMLQFSVHFL SLVYLYREAQ ARSPEKQEQF VDLYKEFEPS LVNSTVYIMA
1110 1120 1130 1140 1150
MAMQMATFAI NYKGPPFMES LPENKPLVWS LAVSLMAIMG LLLGSSPDFN
1160 1170 1180 1190
SQFGLVDIPV EFKLVIGQVL ALDFGLALLA DRVLQFFLGT PKLRVPS
Length:1,197
Mass (Da):131,916
Last modified:November 16, 2011 - v1
Checksum:i4FC6EB2254ED8FC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07024882 Genomic DNA. No translation available.
CH474031 Genomic DNA. Translation: EDL90620.1.
RefSeqiNP_001099549.2. NM_001106079.2.
UniGeneiRn.3697.

Genome annotation databases

EnsembliENSRNOT00000015247; ENSRNOP00000015247; ENSRNOG00000010776.
GeneIDi290673.
KEGGirno:290673.

Similar proteinsi

Entry informationi

Entry nameiG3V7I3_RAT
AccessioniPrimary (citable) accession number: G3V7I3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 22, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported