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Protein

Tumor necrosis factor ligand superfamily member

Gene

LOC103689974

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-5668541 TNFR2 non-canonical NF-kB pathway
R-RNO-5669034 TNFs bind their physiological receptors
R-RNO-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Tumor necrosis factor ligand superfamily memberUniRule annotation
Gene namesi
Name:LOC103689974Imported
Synonyms:Tnfsf11Imported
ORF Names:rCG_36849Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi9144322 LOC103689974

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei48 – 71HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000009559

Interactioni

Subunit structurei

Homotrimer.UniRule annotation

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini167 – 314TNF_2InterPro annotationAdd BLAST148

Sequence similaritiesi

Belongs to the tumor necrosis factor family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEIS Eukaryota
ENOG410YGCE LUCA
GeneTreeiENSGT00530000063443
KOiK05473
OMAiQDATYFG
OrthoDBiEOG091G0F3S
TreeFamiTF332169

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR006052 TNF_dom
IPR017355 TNF_ligand_10/11
IPR008983 Tumour_necrosis_fac-like_dom
PfamiView protein in Pfam
PF00229 TNF, 1 hit
PIRSFiPIRSF038013 TNF10_TNF11, 1 hit
SMARTiView protein in SMART
SM00207 TNF, 1 hit
SUPFAMiSSF49842 SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS50049 TNF_2, 1 hit

Sequencei

Sequence statusi: Complete.

G3V794-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRASRDYGK YLRGSEEMGS CPGVPHEGPL HPAPSAPAPA PPPAASRFMF
60 70 80 90 100
LALLGLGLGQ VVCSIALFLY FRAQMDPNRI SEDSTRCFYR ILRLRENTGL
110 120 130 140 150
QDSTLESEDT EALPDSCRRM KQAFQGAVQR ELQHIVGPQR FSGVPAMMEG
160 170 180 190 200
SWLDVARRGK PEAQPFAHLT INAANIPSGS HKVSLSSWYH DRGWAKISNM
210 220 230 240 250
TLSNGKLRVN QDGFYYLYAN ICFRHHETSG SVPADYLQLM VYVVKTSIKI
260 270 280 290 300
PSSHNLMKGG STKNWSGNSE FHFYSINVGG FFKLRAGEEI SVQVSNPSLL
310
DPDQDATYFG AFKVQDID
Length:318
Mass (Da):35,342
Last modified:November 16, 2011 - v1
Checksum:iFD953E9E0182B11A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07018502 Genomic DNA No translation available.
AC094149 Genomic DNA No translation available.
CH473951 Genomic DNA Translation: EDM02337.1
RefSeqiXP_008769150.1, XM_008770928.2
UniGeneiRn.217570
Rn.64517

Genome annotation databases

EnsembliENSRNOT00000013210; ENSRNOP00000013210; ENSRNOG00000009559
ENSRNOT00000049056; ENSRNOP00000044212; ENSRNOG00000049547
GeneIDi103689974
KEGGirno:103689974

Similar proteinsi

Entry informationi

Entry nameiG3V794_RAT
AccessioniPrimary (citable) accession number: G3V794
Secondary accession number(s): D3ZXV1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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