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G3V6G6

- G3V6G6_RAT

UniProt

G3V6G6 - G3V6G6_RAT

Protein
Submitted name:

Synaptotagmin-like 4, isoform CRA_a

Gene

Sytl4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. phospholipid binding Source: Ensembl
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. exocytosis Source: Ensembl
    2. intracellular protein transport Source: InterPro
    3. multivesicular body sorting pathway Source: Ensembl
    4. negative regulation of insulin secretion Source: Ensembl
    5. positive regulation of exocytosis Source: Ensembl
    6. positive regulation of protein secretion Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Synaptotagmin-like 4, isoform CRA_aImported
    Submitted name:
    Synaptotagmin-like protein 4Imported
    Gene namesi
    Name:Sytl4Imported
    ORF Names:rCG_38145Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome X

    Organism-specific databases

    RGDi620204. Sytl4.

    Subcellular locationi

    GO - Cellular componenti

    1. centrosome Source: Ensembl
    2. endosome Source: Ensembl
    3. extrinsic component of membrane Source: Ensembl
    4. nucleus Source: Ensembl
    5. secretory granule Source: Ensembl

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 C2 domains.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117593.
    KOiK17598.
    OMAiDWFYDQR.
    OrthoDBiEOG7JMGDC.
    TreeFamiTF341184.

    Family and domain databases

    Gene3Di2.60.40.150. 2 hits.
    3.30.40.10. 1 hit.
    InterProiIPR000008. C2_dom.
    IPR028694. SYTL4.
    IPR010911. Znf_FYVE-typ.
    IPR011011. Znf_FYVE_PHD.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PANTHERiPTHR10024:SF9. PTHR10024:SF9. 1 hit.
    PfamiPF00168. C2. 2 hits.
    PF02318. FYVE_2. 1 hit.
    [Graphical view]
    SMARTiSM00239. C2. 2 hits.
    SM00184. RING. 1 hit.
    [Graphical view]
    SUPFAMiSSF49562. SSF49562. 2 hits.
    SSF57903. SSF57903. 1 hit.
    PROSITEiPS50004. C2. 2 hits.
    PS50916. RABBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3V6G6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEILDLSFL SEMERDLILS VLQRDEELRK ADEKRIRRLK NELLEIKRKG    50
    AKRGSQHYSD RTCARCQEGL GRLISKSNTC VGCNHLVCRE CRVLESNGSW 100
    RCKVCSKEIE LKKATGDWFY DQKVNRFAYR TGSDIIRMSL RRKPAVNKRE 150
    TVGQSLLQQT QMGDIWPGRR IIQEQQKEQS VLFEVPKLKS GKSALEAESE 200
    SLDSYTADSD STSRRDSLDK SGLFPEWKKM SAPKSQVEKE IAPGNQNAVC 250
    GDEGDMIFKK NTRKVLRPSE YTKSVIDLRP EDVAQESGIL GDRSKSVPGL 300
    SVDMEEEEEE EEDIDHLVKL HRQKLARGSM QSGSSMSTIG SMMSLYSEAG 350
    DFGNVSVTGK IAFSLKFEQK TQTLVIHVKE CHQLAYADEA KKRSNPYVKT 400
    YLLPDKSRQG KRKTSIKRDT INPLYDETFR YEISESLLAQ RTLQFSVWHH 450
    GRFGRNTFLG EAEVHMDSWK LDKKLDHCLP LHGKISTESS PGLPAHKGEL 500
    VVSLKYIPAS KLPVGGDRKK SKGGEGGELQ VWIKEAKNLT AAKSGGTSDS 550
    FVKGYLLPMR NKASKRKTPV MKKTLNPHYN HTFVYNGVRL EDLQHMCLEL 600
    TVWDREPLAS NDFLGGVRLG VGTGISSGEV VDWMDSTGEE VSLWQKMRQY 650
    PGSWAEGTLQ LRSSMVKQKL GV 672
    Length:672
    Mass (Da):75,914
    Last modified:November 16, 2011 - v1
    Checksum:iE32F94572F3A8E8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06107004 Genomic DNA. No translation available.
    CH473969 Genomic DNA. Translation: EDM07039.1.
    RefSeqiXP_006257275.1. XM_006257213.1.
    XP_006257276.1. XM_006257214.1.
    UniGeneiRn.107417.

    Genome annotation databases

    EnsembliENSRNOT00000004909; ENSRNOP00000004909; ENSRNOG00000003526.
    GeneIDi140594.
    KEGGirno:140594.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06107004 Genomic DNA. No translation available.
    CH473969 Genomic DNA. Translation: EDM07039.1 .
    RefSeqi XP_006257275.1. XM_006257213.1.
    XP_006257276.1. XM_006257214.1.
    UniGenei Rn.107417.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000004909 ; ENSRNOP00000004909 ; ENSRNOG00000003526 .
    GeneIDi 140594.
    KEGGi rno:140594.

    Organism-specific databases

    CTDi 94121.
    RGDi 620204. Sytl4.

    Phylogenomic databases

    GeneTreei ENSGT00750000117593.
    KOi K17598.
    OMAi DWFYDQR.
    OrthoDBi EOG7JMGDC.
    TreeFami TF341184.

    Miscellaneous databases

    NextBioi 35583726.
    PROi G3V6G6.

    Family and domain databases

    Gene3Di 2.60.40.150. 2 hits.
    3.30.40.10. 1 hit.
    InterProi IPR000008. C2_dom.
    IPR028694. SYTL4.
    IPR010911. Znf_FYVE-typ.
    IPR011011. Znf_FYVE_PHD.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    PANTHERi PTHR10024:SF9. PTHR10024:SF9. 1 hit.
    Pfami PF00168. C2. 2 hits.
    PF02318. FYVE_2. 1 hit.
    [Graphical view ]
    SMARTi SM00239. C2. 2 hits.
    SM00184. RING. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49562. SSF49562. 2 hits.
    SSF57903. SSF57903. 1 hit.
    PROSITEi PS50004. C2. 2 hits.
    PS50916. RABBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiG3V6G6_RAT
    AccessioniPrimary (citable) accession number: G3V6G6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3