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Protein
Submitted name:

Protein kinase C eta type

Gene

PRKCH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C eta typeImported
Gene namesi
Name:PRKCHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000027075.13.
HGNCiHGNC:9403. PRKCH.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000027075.

PTM / Processingi

Proteomic databases

MaxQBiG3V4Q6.
PaxDbiG3V4Q6.
PeptideAtlasiG3V4Q6.

Expressioni

Gene expression databases

BgeeiENSG00000027075.
ExpressionAtlasiG3V4Q6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliG3V4Q6.
SMRiG3V4Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 61Phorbol-ester/DAG-typeInterPro annotationAdd BLAST52
Domaini84 – 134Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini194 – 224Protein kinaseInterPro annotationAdd BLAST31

Phylogenomic databases

eggNOGiKOG0694. Eukaryota.
ENOG410XNPH. LUCA.
GeneTreeiENSGT00820000126964.

Family and domain databases

CDDicd00029. C1. 2 hits.
InterProiView protein in InterPro
IPR020454. DAG/PE-bd.
IPR011009. Kinase-like_dom.
IPR002219. PE/DAG-bd.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
PfamiView protein in Pfam
PF00130. C1_1. 2 hits.
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiView protein in SMART
SM00109. C1. 2 hits.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 2 hits.

Sequencei

Sequence statusi: Fragment.

G3V4Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRRVHQING HKFMATYLRQ PTYCSHCREF IWGVFGKQGY QCQVCTCVVH
60 70 80 90 100
KRCHHLIVTA CTCQNNINKV DSKIAEQRFG INIPHKFSIH NYKVPTFCDH
110 120 130 140 150
CGSLLWGIMR QGLQCKICKM NVHIRCQANV APNCGVNAVE LAKTLAGMGL
160 170 180 190 200
QPGNISPTSK LVSRSTLRRQ GKESSKEGNG IGVNSSNRLG IDNFEFIRVL
210 220
GKGSFGKVML ARVKETGDLY AVKV
Length:224
Mass (Da):25,068
Last modified:November 16, 2011 - v1
Checksum:iDBC0162171227E9C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei224Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138996 Genomic DNA. No translation available.
AL355916 Genomic DNA. No translation available.
AL359220 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000557585; ENSP00000451930; ENSG00000027075.
UCSCiuc059cft.1. human.

Similar proteinsi

Entry informationi

Entry nameiG3V4Q6_HUMAN
AccessioniPrimary (citable) accession number: G3V4Q6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 27, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported