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Protein
Submitted name:

Presenilin-1

Gene

PSEN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Presenilin-1Imported
Gene namesi
Name:PSEN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000080815.18.
HGNCiHGNC:9508. PSEN1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080815.

PTM / Processingi

Proteomic databases

MaxQBiG3V449.
PeptideAtlasiG3V449.

Expressioni

Gene expression databases

BgeeiENSG00000080815.
ExpressionAtlasiG3V449. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000016593.

Family and domain databases

InterProiView protein in InterPro
IPR002031. Pept_A22A_PS1.
IPR001108. Peptidase_A22A.
PANTHERiPTHR10202. PTHR10202. 1 hit.
PRINTSiPR01073. PRESENILIN1.

Sequencei

Sequence statusi: Fragment.

G3V449-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELPAPLSY FQNAQMSEDN HLSNTNDNRE RQEHNDRRSL GHPEPLSNGR
60
PQGNSRQVVE QDE
Length:63
Mass (Da):7,273
Last modified:November 16, 2011 - v1
Checksum:i956DFD6E3209669F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei63Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004846 Genomic DNA. No translation available.
AC004858 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000556864; ENSP00000451588; ENSG00000080815.
UCSCiuc059dba.1. human.

Similar proteinsi

Entry informationi

Entry nameiG3V449_HUMAN
AccessioniPrimary (citable) accession number: G3V449
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 25, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported