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Protein
Submitted name:

Protein Z-dependent protease inhibitor

Gene

SERPINA10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Z-dependent protease inhibitorImported
Submitted name:
Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 10, isoform CRA_aImported
Gene namesi
Name:SERPINA10Imported
ORF Names:hCG_22331Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000140093.9
HGNCiHGNC:15996 SERPINA10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140093

PTM / Processingi

Proteomic databases

PeptideAtlasiG3V2W1

Expressioni

Gene expression databases

BgeeiENSG00000140093

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini124 – 481SERPINInterPro annotationAdd BLAST358

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili86 – 106Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
OMAiAFIHKDF
OrthoDBiEOG091G0ION

Family and domain databases

CDDicd02055 PZI, 1 hit
InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
IPR033835 SERPINA10
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 2 hits

Sequencei

Sequence statusi: Complete.

G3V2W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSTQELLG YHCRLQDKLQ EQEGSLAAEG RHSLASAADH MKVVPSLLLS
60 70 80 90 100
VLLAQVWLVP GLAPSPQSPE TPAPQNQTSR VVQAPKEEEE DEQEASEEKA
110 120 130 140 150
SEEEKAWLMA SRQQLAKETS NFGFSLLRKI SMRHDGNMVF SPFGMSLAMT
160 170 180 190 200
GLMLGATGPT ETQIKRGLHL QALKPTKPGL LPSLFKGLRE TLSRNLELGL
210 220 230 240 250
TQGSFAFIHK DFDVKETFFN LSKRYFDTEC VPMNFRNASQ AKRLMNHYIN
260 270 280 290 300
KETRGKIPKL FDEINPETKL ILVDYILFKG KWLTPFDPVF TEVDTFHLDK
310 320 330 340 350
YKTIKVPMMY GAGKFASTFD KNFRCHVLKL PYQGNATMLV VLMEKMGDHL
360 370 380 390 400
ALEDYLTTDL VETWLRNMKT RNMEVFFPKF KLDQKYEMHE LLRQMGIRRI
410 420 430 440 450
FSPFADLSEL SATGRNLQVS RVLQRTVIEV DERGTEAVAG ILSEITAYSM
460 470 480
PPVIKVDRPF HFMIYEETSG MLLFLGRVVN PTLL
Length:484
Mass (Da):55,114
Last modified:November 16, 2011 - v1
Checksum:iA635D581DA23E361
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117259 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81564.1
RefSeqiXP_016876842.1, XM_017021353.1
UniGeneiHs.118620

Genome annotation databases

EnsembliENST00000554723; ENSP00000450896; ENSG00000140093
ENST00000616057; ENSP00000482029; ENSG00000278767
GeneIDi51156
UCSCiuc001yct.4 human

Similar proteinsi

Entry informationi

Entry nameiG3V2W1_HUMAN
AccessioniPrimary (citable) accession number: G3V2W1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 25, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health