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Protein
Submitted name:

Liprin-alpha-2

Gene

PPFIA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Liprin-alpha-2Imported
Gene namesi
Name:PPFIA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:9246. PPFIA2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiG3V200.
PaxDbiG3V200.

Expressioni

Gene expression databases

BgeeiG3V200.
ExpressionAtlasiG3V200. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000450337.

Structurei

3D structure databases

ProteinModelPortaliG3V200.
SMRiG3V200. Positions 871-1182.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini898 – 96467SAM (sterile alpha motif)InterPro annotationAdd
BLAST
Domaini1027 – 108458SAM (sterile alpha motif)InterPro annotationAdd
BLAST
Domaini1108 – 117770SAM (sterile alpha motif)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili35 – 6228Sequence analysisAdd
BLAST
Coiled coili103 – 14442Sequence analysisAdd
BLAST
Coiled coili195 – 22935Sequence analysisAdd
BLAST
Coiled coili270 – 35384Sequence analysisAdd
BLAST
Coiled coili357 – 40650Sequence analysisAdd
BLAST
Coiled coili420 – 46142Sequence analysisAdd
BLAST
Coiled coili505 – 53531Sequence analysisAdd
BLAST
Coiled coili650 – 69142Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0249. Eukaryota.
ENOG410XP8Z. LUCA.
GeneTreeiENSGT00760000119138.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
InterProiIPR029515. Liprin.
IPR030441. PPFIA2.
IPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PANTHERiPTHR12587. PTHR12587. 3 hits.
PTHR12587:SF6. PTHR12587:SF6. 3 hits.
PfamiPF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 3 hits.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 3 hits.
PROSITEiPS50105. SAM_DOMAIN. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3V200-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR
60 70 80 90 100
ETQESLSLAQ QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP
110 120 130 140 150
PEFAALTKEL NACREQLLEK EEEISELKAE RNNTRLLLEH LECLVSRHER
160 170 180 190 200
SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL FEHHKALDEK VRERLRVSLE
210 220 230 240 250
RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE HLEGMEPGQK
260 270 280 290 300
VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
310 320 330 340 350
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA
360 370 380 390 400
QRESTSIHDM NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM
410 420 430 440 450
RKAETLPEVE AELAQRIAAL TKAEERHGNI EERMRHLEGQ LEEKNQELQR
460 470 480 490 500
ARQREKMNEE HNKRLSDTVD RLLTESNERL QLHLKERMAA LEEKNVLIQE
510 520 530 540 550
SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI EPTIPRTHLD
560 570 580 590 600
TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
610 620 630 640 650
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA
660 670 680 690 700
MMLQEQLDAI NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP
710 720 730 740 750
GTSITASVTA SSLASSSPPS GHSTPKLTPR SPAREMDRMG VMTLPSDLRK
760 770 780 790 800
HRRKIAVVEE DGREDKATIK CETSPPPTPR ALRMTHTLPS SYHNDARSSL
810 820 830 840 850
SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK KEKARLGQLR
860 870 880 890 900
GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
910 920 930 940 950
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH
960 970 980 990 1000
RLKLRLAIQE MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE
1010 1020 1030 1040 1050
EGSWAQCPVF LQTLAYGDMN HEWIGNEWLP SLGLPQYRSY FMECLVDARM
1060 1070 1080 1090 1100
LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC LKRLNYDRKE LERRREASQH
1110 1120 1130 1140 1150
EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA LDENFDYSSL
1160 1170 1180 1190 1200
ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
1210 1220 1230 1240
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDDG VFSVYST
Length:1,247
Mass (Da):142,108
Last modified:June 26, 2013 - v2
Checksum:i21C3E8A4099265FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011316 Genomic DNA. No translation available.
AC069228 Genomic DNA. No translation available.
AC078920 Genomic DNA. No translation available.
AC079363 Genomic DNA. No translation available.
AC079408 Genomic DNA. No translation available.
RefSeqiNP_001207402.1. NM_001220473.2.
UniGeneiHs.506216.
Hs.737103.

Genome annotation databases

EnsembliENST00000550584; ENSP00000449558; ENSG00000139220.
GeneIDi8499.
KEGGihsa:8499.
UCSCiuc058rjj.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011316 Genomic DNA. No translation available.
AC069228 Genomic DNA. No translation available.
AC078920 Genomic DNA. No translation available.
AC079363 Genomic DNA. No translation available.
AC079408 Genomic DNA. No translation available.
RefSeqiNP_001207402.1. NM_001220473.2.
UniGeneiHs.506216.
Hs.737103.

3D structure databases

ProteinModelPortaliG3V200.
SMRiG3V200. Positions 871-1182.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000450337.

Proteomic databases

EPDiG3V200.
PaxDbiG3V200.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000550584; ENSP00000449558; ENSG00000139220.
GeneIDi8499.
KEGGihsa:8499.
UCSCiuc058rjj.1. human.

Organism-specific databases

CTDi8499.
HGNCiHGNC:9246. PPFIA2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0249. Eukaryota.
ENOG410XP8Z. LUCA.
GeneTreeiENSGT00760000119138.

Miscellaneous databases

ChiTaRSiPPFIA2. human.
GenomeRNAii8499.
NextBioi35516661.

Gene expression databases

BgeeiG3V200.
ExpressionAtlasiG3V200. baseline and differential.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
InterProiIPR029515. Liprin.
IPR030441. PPFIA2.
IPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PANTHERiPTHR12587. PTHR12587. 3 hits.
PTHR12587:SF6. PTHR12587:SF6. 3 hits.
PfamiPF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 3 hits.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 3 hits.
PROSITEiPS50105. SAM_DOMAIN. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The finished DNA sequence of human chromosome 12."
    Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiG3V200_HUMAN
AccessioniPrimary (citable) accession number: G3V200
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: June 26, 2013
Last modified: March 16, 2016
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.