ID   G3UZU3_MOUSE            Unreviewed;       188 AA.
AC   G3UZU3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Glutamate receptor, metabotropic 7 {ECO:0000313|Ensembl:ENSMUSP00000134635.2};
GN   Name=Grm7 {ECO:0000313|Ensembl:ENSMUSP00000134635.2,
GN   ECO:0000313|MGI:MGI:1351344};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000134635.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000134635.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134635.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000134635.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134635.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3UZU3; -.
DR   SMR; G3UZU3; -.
DR   MaxQB; G3UZU3; -.
DR   PeptideAtlas; G3UZU3; -.
DR   ProteomicsDB; 318240; -.
DR   Antibodypedia; 10079; 466 antibodies from 35 providers.
DR   Ensembl; ENSMUST00000174018.8; ENSMUSP00000134635.2; ENSMUSG00000056755.14.
DR   AGR; MGI:1351344; -.
DR   MGI; MGI:1351344; Grm7.
DR   VEuPathDB; HostDB:ENSMUSG00000056755; -.
DR   GeneTree; ENSGT01030000234648; -.
DR   HOGENOM; CLU_113944_0_0_1; -.
DR   ChiTaRS; Grm7; mouse.
DR   Proteomes; UP000000589; Chromosome 6.
DR   Bgee; ENSMUSG00000056755; Expressed in medial dorsal nucleus of thalamus and 113 other cell types or tissues.
DR   ExpressionAtlas; G3UZU3; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR001883; GPCR_3_mGluR7.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR01057; MTABOTROPC7R.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Proteomics identification {ECO:0007829|MaxQB:G3UZU3,
KW   ECO:0007829|PeptideAtlas:G3UZU3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..188
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003457236"
FT   DOMAIN          78..173
FT                   /note="Receptor ligand binding region"
FT                   /evidence="ECO:0000259|Pfam:PF01094"
SQ   SEQUENCE   188 AA;  20299 MW;  23DF780DE5084305 CRC64;
     MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT LGGLFPVHAK
     GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT LGARILDTCS RDTYALEQSL
     TFVQALIQKD TSDVRCTNGE PPVFVKPEKV VGVIGASGSS VSIMVANILR LFQCLPKNHN
     AMVLNTSD
//