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Protein
Submitted name:

Metabotropic glutamate receptor 7

Gene

Grm7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway Source: MGI
  • adult behavior Source: MGI
  • associative learning Source: MGI
  • behavioral fear response Source: MGI
  • conditioned taste aversion Source: MGI
  • memory Source: MGI
  • multicellular organismal response to stress Source: MGI
  • negative regulation of adenylate cyclase activity Source: MGI
  • negative regulation of cAMP biosynthetic process Source: MGI
  • neurological system process Source: MGI
  • regulation of cyclase activity Source: MGI
  • regulation of synaptic transmission, glutamatergic Source: GO_Central
  • sensory perception of sound Source: MGI
  • short-term memory Source: MGI
  • synaptic transmission Source: MGI
  • transmission of nerve impulse Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

ReceptorSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Metabotropic glutamate receptor 7Imported
Gene namesi
Name:Grm7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1351344. Grm7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiG3UZU3.
ExpressionAtlasiG3UZU3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000133957.

Structurei

3D structure databases

ProteinModelPortaliG3UZU3.
SMRiG3UZU3. Positions 40-173.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118884.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

G3UZU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT
60 70 80 90 100
LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT
110 120 130 140 150
LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV
160 170 180
VGVIGASGSS VSIMVANILR LFQCLPKNHN AMVLNTSD
Length:188
Mass (Da):20,299
Last modified:November 16, 2011 - v1
Checksum:i23DF780DE5084305
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000174018; ENSMUSP00000134635; ENSMUSG00000056755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliG3UZU3.
SMRiG3UZU3. Positions 40-173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000133957.

Chemistry

BindingDBiG3UZU3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000174018; ENSMUSP00000134635; ENSMUSG00000056755.

Organism-specific databases

MGIiMGI:1351344. Grm7.

Phylogenomic databases

GeneTreeiENSGT00760000118884.

Miscellaneous databases

NextBioi35560998.
SOURCEiSearch...

Gene expression databases

BgeeiG3UZU3.
ExpressionAtlasiG3UZU3. baseline and differential.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UZU3_MOUSE
AccessioniPrimary (citable) accession number: G3UZU3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 24, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.