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Protein
Submitted name:

Pituitary homeobox 1

Gene

Pitx1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • branchiomeric skeletal muscle development Source: MGI
  • cartilage development Source: MGI
  • embryonic hindlimb morphogenesis Source: MGI
  • hindlimb morphogenesis Source: MGI
  • myoblast fate commitment Source: MGI
  • pituitary gland development Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • skeletal system development Source: MGI
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pituitary homeobox 1Imported
Gene namesi
Name:Pitx1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:107374. Pitx1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

  • cytoplasm Source: MGI
  • nucleolus Source: MGI
  • nucleus Source: MGI
  • transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiG3UZS0.
ExpressionAtlasiG3UZS0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021968.

Family & Domainsi

Keywords - Domaini

HomeoboxUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118908.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

G3UZS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAFKGGMSL ERLPEGLRPP PPPPHDMGPS FHLARAADPR EPLENSASES
60 70 80 90 100
SDADLPDKER GGEAKGPEDG GAGSAGCGGG AEDPAKKKKQ RRQRTHFTSQ
110 120
QLQELEATFQ RNRYPDMSMR EEIA
Length:124
Mass (Da):13,455
Last modified:May 27, 2015 - v5
Checksum:i816C5618A0D4484E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei124 – 1241Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129780 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000173618; ENSMUSP00000134609; ENSMUSG00000021506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129780 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021968.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000173618; ENSMUSP00000134609; ENSMUSG00000021506.

Organism-specific databases

MGIiMGI:107374. Pitx1.

Phylogenomic databases

GeneTreeiENSGT00760000118908.

Miscellaneous databases

NextBioi35560979.
SOURCEiSearch...

Gene expression databases

BgeeiG3UZS0.
ExpressionAtlasiG3UZS0. baseline and differential.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UZS0_MOUSE
AccessioniPrimary (citable) accession number: G3UZS0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: May 27, 2015
Last modified: June 24, 2015
This is version 31 of the entry and version 5 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.