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G3UZL5

- G3UZL5_MOUSE

UniProt

G3UZL5 - G3UZL5_MOUSE

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Protein
Submitted name:

Disks large homolog 4

Gene

Dlg4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. protein localization to synapse Source: MGI
  2. regulation of long-term neuronal synaptic plasticity Source: MGI
  3. synaptic vesicle maturation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Disks large homolog 4Imported
Gene namesi
Name:Dlg4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1277959. Dlg4.

Subcellular locationi

GO - Cellular componenti

  1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: MGI
  2. cell junction Source: MGI
  3. cerebellar mossy fiber Source: MGI
  4. cytoplasm Source: MGI
  5. dendrite Source: MGI
  6. endoplasmic reticulum Source: MGI
  7. excitatory synapse Source: MGI
  8. extrinsic component of cytoplasmic side of plasma membrane Source: MGI
  9. juxtaparanode region of axon Source: MGI
  10. membrane Source: MGI
  11. neuronal postsynaptic density Source: MGI
  12. neuron projection terminus Source: MGI
  13. neuron spine Source: MGI
  14. plasma membrane Source: MGI
  15. postsynaptic density Source: MGI
  16. synapse Source: MGI
  17. synaptic membrane Source: MGI
  18. synaptic vesicle Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiG3UZL5.
ExpressionAtlasiG3UZL5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliG3UZL5.
SMRiG3UZL5. Positions 10-202.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains SH3 domain.SAAS annotation
Contains SHdomain.SAAS annotation

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118866.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR23119. PTHR23119. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

G3UZL5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ASLRSNPKRG FYIRALFDYD KTKDCGFLSQ ALSFHFGDVL HVIDASDEEW
60 70 80 90 100
WQARRVHSDS ETDDIGFIPS KRRVERREWS RLKAKDWGSS SGSQGREDSV
110 120 130 140 150
LSYETVTQME VHYARPIIIL GPTKDRANDD LLSEFPDKFG SCVPHTTRPK
160 170 180 190 200
REYEIDGRDY HFVSSREKME KDIQAHKFIE AGQYNSHLYG TSVQSVREVA

EQRDQ
Length:205
Mass (Da):23,796
Last modified:November 16, 2011 - v1
Checksum:iDCC9338C30743ED0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596185 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000123687; ENSMUSP00000134545; ENSMUSG00000020886.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596185 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali G3UZL5.
SMRi G3UZL5. Positions 10-202.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000123687 ; ENSMUSP00000134545 ; ENSMUSG00000020886 .

Organism-specific databases

MGIi MGI:1277959. Dlg4.

Phylogenomic databases

GeneTreei ENSGT00760000118866.

Miscellaneous databases

ChiTaRSi DLG4. mouse.
NextBioi 35560933.
SOURCEi Search...

Gene expression databases

Bgeei G3UZL5.
ExpressionAtlasi G3UZL5. baseline and differential.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view ]
PANTHERi PTHR23119. PTHR23119. 1 hit.
Pfami PF00625. Guanylate_kin. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view ]
SMARTi SM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
    Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
    J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UZL5_MOUSE
AccessioniPrimary (citable) accession number: G3UZL5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3