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G3UZL5

- G3UZL5_MOUSE

UniProt

G3UZL5 - G3UZL5_MOUSE

Protein
Submitted name:

Disks large homolog 4

Gene

Dlg4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. protein localization to synapse Source: MGI
    2. regulation of long-term neuronal synaptic plasticity Source: MGI
    3. synaptic vesicle maturation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Disks large homolog 4Imported
    Gene namesi
    Name:Dlg4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1277959. Dlg4.

    Subcellular locationi

    GO - Cellular componenti

    1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: MGI
    2. cell junction Source: MGI
    3. cerebellar mossy fiber Source: MGI
    4. cytoplasm Source: MGI
    5. dendrite Source: MGI
    6. endoplasmic reticulum Source: MGI
    7. excitatory synapse Source: MGI
    8. extrinsic component of cytoplasmic side of plasma membrane Source: MGI
    9. juxtaparanode region of axon Source: MGI
    10. membrane Source: MGI
    11. neuronal postsynaptic density Source: MGI
    12. neuron projection terminus Source: MGI
    13. neuron spine Source: MGI
    14. plasma membrane Source: MGI
    15. postsynaptic density Source: MGI
    16. synapse Source: MGI
    17. synaptic vesicle Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiG3UZL5.
    BgeeiG3UZL5.

    Structurei

    3D structure databases

    ProteinModelPortaliG3UZL5.
    SMRiG3UZL5. Positions 10-202.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains SH3 domain.SAAS annotation
    Contains SHdomain.SAAS annotation

    Keywords - Domaini

    SH3 domainSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00660000095130.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR016313. DLG1.
    IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view]
    PANTHERiPTHR23119. PTHR23119. 1 hit.
    PfamiPF00625. Guanylate_kin. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    SSF52540. SSF52540. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    G3UZL5-1 [UniParc]FASTAAdd to Basket

    « Hide

    ASLRSNPKRG FYIRALFDYD KTKDCGFLSQ ALSFHFGDVL HVIDASDEEW    50
    WQARRVHSDS ETDDIGFIPS KRRVERREWS RLKAKDWGSS SGSQGREDSV 100
    LSYETVTQME VHYARPIIIL GPTKDRANDD LLSEFPDKFG SCVPHTTRPK 150
    REYEIDGRDY HFVSSREKME KDIQAHKFIE AGQYNSHLYG TSVQSVREVA 200
    EQRDQ 205
    Length:205
    Mass (Da):23,796
    Last modified:November 16, 2011 - v1
    Checksum:iDCC9338C30743ED0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596185 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000123687; ENSMUSP00000134545; ENSMUSG00000020886.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596185 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali G3UZL5.
    SMRi G3UZL5. Positions 10-202.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000123687 ; ENSMUSP00000134545 ; ENSMUSG00000020886 .

    Organism-specific databases

    MGIi MGI:1277959. Dlg4.

    Phylogenomic databases

    GeneTreei ENSGT00660000095130.

    Miscellaneous databases

    ChiTaRSi DLG4. mouse.
    NextBioi 35560933.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi G3UZL5.
    Bgeei G3UZL5.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR016313. DLG1.
    IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view ]
    PANTHERi PTHR23119. PTHR23119. 1 hit.
    Pfami PF00625. Guanylate_kin. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    SSF52540. SSF52540. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
      J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG3UZL5_MOUSE
    AccessioniPrimary (citable) accession number: G3UZL5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3