ID   G3UZ52_MOUSE            Unreviewed;       213 AA.
AC   G3UZ52;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Gamma-aminobutyric acid (GABA) B receptor, 1 {ECO:0000313|Ensembl:ENSMUSP00000134346.2};
DE   Flags: Fragment;
GN   Name=Gabbr1 {ECO:0000313|Ensembl:ENSMUSP00000134346.2,
GN   ECO:0000313|MGI:MGI:1860139};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000134346.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000134346.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134346.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000134346.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134346.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3UZ52; -.
DR   SMR; G3UZ52; -.
DR   MaxQB; G3UZ52; -.
DR   PeptideAtlas; G3UZ52; -.
DR   ProteomicsDB; 328445; -.
DR   Antibodypedia; 50418; 628 antibodies from 44 providers.
DR   Ensembl; ENSMUST00000174347.2; ENSMUSP00000134346.2; ENSMUSG00000024462.18.
DR   AGR; MGI:1860139; -.
DR   MGI; MGI:1860139; Gabbr1.
DR   VEuPathDB; HostDB:ENSMUSG00000024462; -.
DR   GeneTree; ENSGT00940000157642; -.
DR   HOGENOM; CLU_1297027_0_0_1; -.
DR   ChiTaRS; Gabbr1; mouse.
DR   Proteomes; UP000000589; Chromosome 17.
DR   Bgee; ENSMUSG00000024462; Expressed in habenula and 256 other cell types or tissues.
DR   ExpressionAtlas; G3UZ52; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR   CDD; cd06366; PBP1_GABAb_receptor; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR002455; GPCR3_GABA-B.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR   PANTHER; PTHR10519:SF76; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Proteomics identification {ECO:0007829|MaxQB:G3UZ52,
KW   ECO:0007829|PeptideAtlas:G3UZ52};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..213
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003456700"
FT   DOMAIN          103..213
FT                   /note="Receptor ligand binding region"
FT                   /evidence="ECO:0000259|Pfam:PF01094"
FT   NON_TER         213
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000134346.2"
SQ   SEQUENCE   213 AA;  23815 MW;  FF64CA3F52007BEB CRC64;
     MGPGGPCTPV GWPLPLLLVM AAGVAPVWAS HSPHLPRPHP RVPPHPSSER RAVYIGALFP
     MSGGWPGGQA CQPAVEMALE DVNSRRDILP DYELKLIHHD SKLSYGSSSP ALSNRQRFPT
     FFRTHPSATL HNPTRVKLFE KWGWKKIATI QQTTEVFTST LDDLEERVKE AGIEITFRQS
     FFSDPAVPVK NLKRQDARII VGLFYETEAR KVF
//