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Protein
Submitted name:

Nuclear receptor ROR-alpha

Gene

Rora

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. core promoter sequence-specific DNA binding Source: MGI
  2. direct ligand regulated sequence-specific DNA binding transcription factor activity Source: MGI
  3. DNA binding Source: MGI
  4. oxysterol binding Source: MGI
  5. sequence-specific DNA binding Source: MGI
  6. sequence-specific DNA binding transcription factor activity Source: MGI
  7. transcription coactivator binding Source: MGI
  8. transcription corepressor binding Source: MGI
  9. transcription factor binding Source: MGI

GO - Biological processi

  1. angiogenesis Source: MGI
  2. cellular response to hypoxia Source: MGI
  3. cellular response to sterol Source: MGI
  4. cerebellar Purkinje cell differentiation Source: MGI
  5. cGMP metabolic process Source: MGI
  6. intracellular receptor signaling pathway Source: MGI
  7. muscle cell differentiation Source: MGI
  8. negative regulation of I-kappaB kinase/NF-kappaB signaling Source: MGI
  9. negative regulation of inflammatory response Source: MGI
  10. nitric oxide biosynthetic process Source: MGI
  11. positive regulation of transcription, DNA-templated Source: MGI
  12. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  13. positive regulation vascular endothelial growth factor production Source: MGI
  14. regulation of macrophage activation Source: MGI
  15. regulation of transcription, DNA-templated Source: MGI
  16. triglyceride homeostasis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor ROR-alphaImported
Gene namesi
Name:RoraImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:104661. Rora.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiG3UZ02.
ExpressionAtlasiG3UZ02. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00780000121834.

Sequencei

Sequence statusi: Fragment.

G3UZ02-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TPLTQDTGRK SEAPGAGRRQ SYASSSRGIS VTKKTHTWQA WYRELPCTAL
60
PMSSSLAWRD PL
Length:62
Mass (Da):6,879
Last modified:November 16, 2011 - v1
Checksum:iF32902BA3FBA1A4C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102602 Genomic DNA. No translation available.
AC127262 Genomic DNA. No translation available.
AC155931 Genomic DNA. No translation available.
AC160977 Genomic DNA. No translation available.
CT009708 Genomic DNA. No translation available.
CT030683 Genomic DNA. No translation available.
CT030730 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000174296; ENSMUSP00000134291; ENSMUSG00000032238.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102602 Genomic DNA. No translation available.
AC127262 Genomic DNA. No translation available.
AC155931 Genomic DNA. No translation available.
AC160977 Genomic DNA. No translation available.
CT009708 Genomic DNA. No translation available.
CT030683 Genomic DNA. No translation available.
CT030730 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000174296; ENSMUSP00000134291; ENSMUSG00000032238.

Organism-specific databases

MGIiMGI:104661. Rora.

Phylogenomic databases

GeneTreeiENSGT00780000121834.

Miscellaneous databases

ChiTaRSiRora. mouse.
NextBioi35560762.
SOURCEiSearch...

Gene expression databases

BgeeiG3UZ02.
ExpressionAtlasiG3UZ02. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UZ02_MOUSE
AccessioniPrimary (citable) accession number: G3UZ02
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.