G3UYM3 (G3UYM3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase LATS2 Ensembl ENSMUSP00000134142

Gene names

Name:

Lats2 Ensembl ENSMUSP00000134142 MGI 1354386

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000134142

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	288 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000134142

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular protein localization Inferred from direct assay PubMed 19289085. Source: MGI hippo signaling cascade Inferred from genetic interaction PubMed 18369314. Source: MGI keratinocyte differentiation Inferred from genetic interaction PubMed 18369314. Source: MGI negative regulation of canonical Wnt receptor signaling pathway Inferred from genetic interaction PubMed 21512031. Source: MGI protein phosphorylation Inferred from direct assay PubMed 19289085. Source: MGI regulation of organ growth Inferred from mutant phenotype PubMed 21512031. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSMUSP00000134142
	Non-terminal residue	288	1	Ensembl ENSMUSP00000134142

Sequences

	Sequence		Length	Mass (Da)
	G3UYM3 [UniParc]. Last modified November 16, 2011. Version 1. Checksum: 645C096917CF7E74	FASTA	288	32,095
	10 20 30 40 50 60 PSRTNSFNNP QPEPSLPAPN TVTAVTAAHI LHPVKSVRVL RPEPQTAVGP SHPAWVAAPT 70 80 90 100 110 120 APATESLETK EGSAGPHPLD VDYGGSERRC PPPPYPKHLL LPSKSEQYSV DLDSLCTSVQ 130 140 150 160 170 180 QSLRGGTEQD RSDKSHKGAK GDKAGRDKKQ IQTSPVPVRK NSRDEEKRES RIKSYSPYAF 190 200 210 220 230 240 KFFMEQHVEN VIKTYQQKAG LCEAEQEQMR KILYQKESNY NRLKRAKMDK SMFVKIKTLG 250 260 270 280 IGAFGEVCLA CKLDTHALYA MKTLRKKDVL NRNQVAHVKA ERDILAEA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000134142.
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000134142.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC154504 Genomic DNA. No translation available.
3D structure databases
ProteinModelPortal	G3UYM3.
SMR	G3UYM3. Positions 227-270.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000173964; ENSMUSP00000134142; ENSMUSG00000021959.
Organism-specific databases
MGI	MGI:1354386. Lats2.
Phylogenomic databases
GeneTree	ENSGT00700000104041.
Gene expression databases
ArrayExpress	G3UYM3.
Bgee	G3UYM3.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LATS2. mouse.
NextBio	35560650.
SOURCE	Search...

Entry information

Entry name

G3UYM3_MOUSE

Accession

Primary (citable) accession number: G3UYM3

Entry history

Integrated into UniProtKB/TrEMBL:	November 16, 2011
Last sequence update:	November 16, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)