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G3UY72

- G3UY72_MOUSE

UniProt

G3UY72 - G3UY72_MOUSE

Protein
Submitted name:

Alpha-aminoadipic semialdehyde dehydrogenase

Gene

Aldh7a1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. oxidoreductase activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Alpha-aminoadipic semialdehyde dehydrogenaseImported
    Gene namesi
    Name:Aldh7a1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:108186. Aldh7a1.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiG3UY72.
    BgeeiG3UY72.

    Structurei

    3D structure databases

    ProteinModelPortaliG3UY72.
    SMRiG3UY72. Positions 28-279.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00720000108597.

    Family and domain databases

    Gene3Di3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    G3UY72-1 [UniParc]FASTAAdd to Basket

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    RVPRRLCVQS VKTSKLSGPW SRPAAHMSTL LIHHPQYAWL QDLGLREDNE    50
    GVYNGSWGGR GEVITTYCPA NNEPIARVRQ ASLKDYEETI GKAKKAWNIW 100
    ADIPAPKRGE IVRKIGDAFR EKIQLLGRLV SLEMGKILVE GIGEVQEYVD 150
    VCDYAAGLSR MIGGPTLPSE RPGHALIEMW NPLGLVGIIT AFNFPVAVFG 200
    WNNAIALITG NVCLWKGAPT TSLVSVAVTK IIAQVLEDNL LPGAICSLVC 250
    GGADIGTTMA RDERVNLLSF TGSTQVGKEG KACWSLEETM PLLLSRTRTS 300
    AWLFRQFCLP PWEQLGKGVP L 321
    Length:321
    Mass (Da):35,133
    Last modified:November 16, 2011 - v1
    Checksum:i555F70E101182744
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC162035 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000174704; ENSMUSP00000133970; ENSMUSG00000053644.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC162035 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali G3UY72.
    SMRi G3UY72. Positions 28-279.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000174704 ; ENSMUSP00000133970 ; ENSMUSG00000053644 .

    Organism-specific databases

    MGIi MGI:108186. Aldh7a1.

    Phylogenomic databases

    GeneTreei ENSGT00720000108597.

    Miscellaneous databases

    NextBioi 35560526.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi G3UY72.
    Bgeei G3UY72.

    Family and domain databases

    Gene3Di 3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J., Newman J.C., Held J.M., Cusack M.P., Sorensen D.J., Li B., Schilling B., Mooney S.D., Kahn C.R., Verdin E., Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A. 110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiG3UY72_MOUSE
    AccessioniPrimary (citable) accession number: G3UY72
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3