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G3UY24

- G3UY24_MOUSE

UniProt

G3UY24 - G3UY24_MOUSE

Protein
Submitted name:

Steroid hormone receptor ERR1

Gene

Esrra

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. sequence-specific DNA binding Source: InterPro
    3. sequence-specific DNA binding transcription factor activity Source: MGI
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. cartilage development Source: Ensembl
    2. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    3. regulation of cell proliferation Source: Ensembl
    4. regulation of osteoblast differentiation Source: Ensembl
    5. regulation of osteoclast differentiation Source: Ensembl
    6. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulationSAAS annotation

    Keywords - Ligandi

    DNA-bindingSAAS annotation, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Steroid hormone receptor ERR1Imported
    Gene namesi
    Name:EsrraImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 19

    Organism-specific databases

    MGIiMGI:1346831. Esrra.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: MGI

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiG3UY24.
    BgeeiG3UY24.

    Structurei

    3D structure databases

    ProteinModelPortaliG3UY24.
    SMRiG3UY24. Positions 73-103.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the nuclear hormone receptor family.UniRule annotation
    Contains nuclear receptor DNA-binding domain.SAAS annotation

    Keywords - Domaini

    Zinc-fingerSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00730000110346.

    Family and domain databases

    Gene3Di3.30.50.10. 1 hit.
    InterProiIPR001628. Znf_hrmn_rcpt.
    IPR013088. Znf_NHR/GATA.
    [Graphical view]
    PfamiPF00105. zf-C4. 1 hit.
    [Graphical view]
    PRINTSiPR00047. STROIDFINGER.
    SMARTiSM00399. ZnF_C4. 1 hit.
    [Graphical view]
    PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    G3UY24-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSQVVGIEP LYIKAEPASP DSPKGSSETE TEPPVTLASG PAPARCLPGH    50
    KEEEDGEGAG SGEQGSGKLV LSSLPKRLCL VCGDVASGYH YGVASCEACK 100
    AFF 103
    Length:103
    Mass (Da):10,511
    Last modified:November 16, 2011 - v1
    Checksum:i71FB175A823AD4FA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei103 – 1031Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC120557 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000172975; ENSMUSP00000133916; ENSMUSG00000024955.
    UCSCiuc008gjh.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC120557 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali G3UY24.
    SMRi G3UY24. Positions 73-103.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000172975 ; ENSMUSP00000133916 ; ENSMUSG00000024955 .
    UCSCi uc008gjh.1. mouse.

    Organism-specific databases

    MGIi MGI:1346831. Esrra.

    Phylogenomic databases

    GeneTreei ENSGT00730000110346.

    Miscellaneous databases

    NextBioi 35560487.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi G3UY24.
    Bgeei G3UY24.

    Family and domain databases

    Gene3Di 3.30.50.10. 1 hit.
    InterProi IPR001628. Znf_hrmn_rcpt.
    IPR013088. Znf_NHR/GATA.
    [Graphical view ]
    Pfami PF00105. zf-C4. 1 hit.
    [Graphical view ]
    PRINTSi PR00047. STROIDFINGER.
    SMARTi SM00399. ZnF_C4. 1 hit.
    [Graphical view ]
    PROSITEi PS51030. NUCLEAR_REC_DBD_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG3UY24_MOUSE
    AccessioniPrimary (citable) accession number: G3UY24
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3