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Protein
Submitted name:

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Gene

Enpp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Imported
Gene namesi
Name:Enpp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1321390. Enpp2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3019HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiG3UXY9.
PaxDbiG3UXY9.

Expressioni

Gene expression databases

BgeeiG3UXY9.
ExpressionAtlasiG3UXY9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000128941.

Structurei

3D structure databases

ProteinModelPortaliG3UXY9.
SMRiG3UXY9. Positions 51-907.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini54 – 9744SMB (somatomedin-B)InterPro annotationAdd
BLAST
Domaini98 – 14245SMB (somatomedin-B)InterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2645. Eukaryota.
COG1524. LUCA.
GeneTreeiENSGT00760000119157.

Family and domain databases

Gene3Di3.40.570.10. 1 hit.
3.40.720.10. 2 hits.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR001604. DNA/RNA_non-sp_Endonuclease.
IPR024873. E-NPP.
IPR029881. ENPP2.
IPR020821. Extracellular_endonuc_su_A.
IPR002591. Phosphodiest/P_Trfase.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PANTHERiPTHR10151. PTHR10151. 2 hits.
PTHR10151:SF21. PTHR10151:SF21. 2 hits.
PfamiPF01223. Endonuclease_NS. 1 hit.
PF01663. Phosphodiest. 1 hit.
PF01033. Somatomedin_B. 2 hits.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00892. Endonuclease_NS. 1 hit.
SM00477. NUC. 1 hit.
SM00201. SO. 2 hits.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF90188. SSF90188. 2 hits.
PROSITEiPS00524. SMB_1. 2 hits.
PS50958. SMB_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3UXY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARQGCFGSY QVISLFTFAI GVNLCLGFTA SRIKRAEWDE GPPTVLSDSP
60 70 80 90 100
WTNTSGSCKG RCFELQEVGP PDCRCDNLCK SYSSCCHDFD ELCLKTARGW
110 120 130 140 150
ECTKDRCGEV RNEENACHCS EDCLSRGDCC TNYQVVCKGE SHWVDDDCEE
160 170 180 190 200
IRVPECPAGF VRPPLIIFSV DGFRASYMKK GSKVMPNIEK LRSCGTHAPY
210 220 230 240 250
MRPVYPTKTF PNLYTLATGL YPESHGIVGN SMYDPVFDAT FHLRGREKFN
260 270 280 290 300
HRWWGGQPLW ITATKQGVRA GTFFWSVSIP HERRILTILQ WLSLPDNERP
310 320 330 340 350
SVYAFYSEQP DFSGHKYGPF GPEESSYGSP LTPAKRPKRK VAPKRRQERP
360 370 380 390 400
VAPPKKRRRK LHRMDHYTAE TRQDKMTNPL REIDKTVGQL MDGLKQLKLH
410 420 430 440 450
RCVNVIFVGD HGMEDVTCDR TEFLSNYLTN VDDITLVPGT LGRIRPKIPN
460 470 480 490 500
NLKYDPKAII ANLTCKKPDQ HFKPYMKQHL PKRLHYANNR RIEDLHLLVE
510 520 530 540 550
RRWHVARKPL DVYKKPSGKC FFQGDHGFDN KVNSMQTVFV GYGPTFKYRT
560 570 580 590 600
KVPPFENIEL YNVMCDLLGL KPAPNNGTHG SLNHLLRTNT FRPTLPEEVS
610 620 630 640 650
RPNYPGIMYL QSDFDLGCTC DDKNKLEELN KRLHTKGSTE ERHLLYGRPA
660 670 680 690 700
VLYRTSYDIL YHTDFESGYS EIFLMPLWTS YTISKQAEVS SIPEHLTNCV
710 720 730 740 750
RPDVRVSPGF SQNCLAYKND KQMSYGFLFP PYLSSSPEAK YDAFLVTNMV
760 770 780 790 800
PMYPAFKRVW TYFQRVLVKK YASERNGVNV ISGPIFDYNY NGLRDIEDEI
810 820 830 840 850
KQYVEGSSIP VPTHYYSIIT SCLDFTQPAD KCDGPLSVSS FILPHRPDND
860 870 880 890 900
ESCNSSEDES KWVEELMKMH TARVRDIEHL TGLDFYRKTS RSYSEILTLK
910
TYLHTYESEI
Length:910
Mass (Da):104,635
Last modified:November 16, 2011 - v1
Checksum:i7F0252EC6890ED0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123644 Genomic DNA. No translation available.
RefSeqiNP_001272924.1. NM_001285995.2.
UniGeneiMm.250256.

Genome annotation databases

EnsembliENSMUST00000173516; ENSMUSP00000133877; ENSMUSG00000022425.
GeneIDi18606.
UCSCiuc007vrp.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123644 Genomic DNA. No translation available.
RefSeqiNP_001272924.1. NM_001285995.2.
UniGeneiMm.250256.

3D structure databases

ProteinModelPortaliG3UXY9.
SMRiG3UXY9. Positions 51-907.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000128941.

Proteomic databases

MaxQBiG3UXY9.
PaxDbiG3UXY9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000173516; ENSMUSP00000133877; ENSMUSG00000022425.
GeneIDi18606.
UCSCiuc007vrp.3. mouse.

Organism-specific databases

CTDi5168.
MGIiMGI:1321390. Enpp2.

Phylogenomic databases

eggNOGiKOG2645. Eukaryota.
COG1524. LUCA.
GeneTreeiENSGT00760000119157.

Miscellaneous databases

ChiTaRSiEnpp2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiG3UXY9.
ExpressionAtlasiG3UXY9. baseline and differential.

Family and domain databases

Gene3Di3.40.570.10. 1 hit.
3.40.720.10. 2 hits.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR001604. DNA/RNA_non-sp_Endonuclease.
IPR024873. E-NPP.
IPR029881. ENPP2.
IPR020821. Extracellular_endonuc_su_A.
IPR002591. Phosphodiest/P_Trfase.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PANTHERiPTHR10151. PTHR10151. 2 hits.
PTHR10151:SF21. PTHR10151:SF21. 2 hits.
PfamiPF01223. Endonuclease_NS. 1 hit.
PF01663. Phosphodiest. 1 hit.
PF01033. Somatomedin_B. 2 hits.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00892. Endonuclease_NS. 1 hit.
SM00477. NUC. 1 hit.
SM00201. SO. 2 hits.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF90188. SSF90188. 2 hits.
PROSITEiPS00524. SMB_1. 2 hits.
PS50958. SMB_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UXY9_MOUSE
AccessioniPrimary (citable) accession number: G3UXY9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 8, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.