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G3UXK2

- G3UXK2_MOUSE

UniProt

G3UXK2 - G3UXK2_MOUSE

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Protein
Submitted name:

Neurexin-1

Gene

Nrxn1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. acetylcholine receptor binding Source: MGI
  2. calcium channel regulator activity Source: MGI

GO - Biological processi

  1. neurotransmitter secretion Source: MGI
  2. positive regulation of synapse assembly Source: MGI
  3. positive regulation of synapse maturation Source: MGI
  4. regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
  5. synapse assembly Source: MGI
  6. synaptic transmission Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neurexin-1Imported
Gene namesi
Name:Nrxn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1096391. Nrxn1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. presynaptic membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiG3UXK2.
ExpressionAtlasiG3UXK2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliG3UXK2.
SMRiG3UXK2. Positions 84-259.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118991.
KOiK07377.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PfamiPF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3UXK2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYQRMLRCGA DLGSPGGGSG GGAGGRLALI WIVPLTLSGL LGVAWGASSL
60 70 80 90 100
GAHHIHHFHG SSKHHSVPIA IYRSPASLRG GHAGTTYIFS KGGGQITYKW
110 120 130 140 150
PPNDRPSTRA DRLAIGFSTV QKEAVLVRVD SSSGLGDYLE LHIHQGKIGV
160 170 180 190 200
KFNVGTDDIA IEESNAIIND GKYHVVRFTR SGGNATLQVD SWPVIERYPA
210 220 230 240 250
GRQLTIFNSQ ATIIIGGKEQ GQPFQGQLSG LYYNGLKVLN MAAENDANIA
260 270 280 290 300
IVGNVRLVGE VPSSMTTEST ATAMQSEMST SIMETTTTLA TSTARRGKPP
310 320 330 340 350
TKEPISQTTD DILVASAECP SDDEDIDPCE PSSGGLANPT RVGGREPYPG
360 370 380 390 400
SAEVIRESSS TTGMVVGIVA AAALCILILL YAMYKYRNRD EGSYHVDESR
410 420 430
NYISNSAQSN GAVVKEKQPS SAKSANKNKK NKDKEYYV
Length:438
Mass (Da):46,660
Last modified:November 16, 2011 - v1
Checksum:i75DD733041D40A8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.
RefSeqiXP_006523881.1. XM_006523818.1.
UniGeneiMm.491332.

Genome annotation databases

EnsembliENSMUST00000174337; ENSMUSP00000133724; ENSMUSG00000024109.
GeneIDi18189.
KEGGimmu:18189.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.
RefSeqi XP_006523881.1. XM_006523818.1.
UniGenei Mm.491332.

3D structure databases

ProteinModelPortali G3UXK2.
SMRi G3UXK2. Positions 84-259.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000174337 ; ENSMUSP00000133724 ; ENSMUSG00000024109 .
GeneIDi 18189.
KEGGi mmu:18189.

Organism-specific databases

CTDi 9378.
MGIi MGI:1096391. Nrxn1.

Phylogenomic databases

GeneTreei ENSGT00760000118991.
KOi K07377.

Miscellaneous databases

ChiTaRSi Nrxn1. mouse.
NextBioi 35560350.
SOURCEi Search...

Gene expression databases

Bgeei G3UXK2.
ExpressionAtlasi G3UXK2. baseline and differential.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view ]
Pfami PF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view ]
SMARTi SM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
PROSITEi PS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UXK2_MOUSE
AccessioniPrimary (citable) accession number: G3UXK2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 26, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3