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G3UXK2

- G3UXK2_MOUSE

UniProt

G3UXK2 - G3UXK2_MOUSE

Protein
Submitted name:

Neurexin-1

Gene

Nrxn1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. acetylcholine receptor binding Source: MGI
    2. calcium channel regulator activity Source: MGI
    3. protein binding Source: MGI

    GO - Biological processi

    1. neurotransmitter secretion Source: MGI
    2. positive regulation of synapse assembly Source: MGI
    3. positive regulation of synapse maturation Source: MGI
    4. regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
    5. synapse assembly Source: MGI
    6. synaptic transmission Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Neurexin-1Imported
    Gene namesi
    Name:Nrxn1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1096391. Nrxn1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. presynaptic membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    BgeeiG3UXK2.

    Structurei

    3D structure databases

    ProteinModelPortaliG3UXK2.
    SMRiG3UXK2. Positions 84-259.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117263.
    KOiK07377.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001791. Laminin_G.
    IPR003585. Neurexin-like.
    IPR027789. Syndecan/Neurexin_dom.
    [Graphical view]
    PfamiPF02210. Laminin_G_2. 1 hit.
    PF01034. Syndecan. 1 hit.
    [Graphical view]
    SMARTiSM00294. 4.1m. 1 hit.
    SM00282. LamG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3UXK2-1 [UniParc]FASTAAdd to Basket

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    MYQRMLRCGA DLGSPGGGSG GGAGGRLALI WIVPLTLSGL LGVAWGASSL    50
    GAHHIHHFHG SSKHHSVPIA IYRSPASLRG GHAGTTYIFS KGGGQITYKW 100
    PPNDRPSTRA DRLAIGFSTV QKEAVLVRVD SSSGLGDYLE LHIHQGKIGV 150
    KFNVGTDDIA IEESNAIIND GKYHVVRFTR SGGNATLQVD SWPVIERYPA 200
    GRQLTIFNSQ ATIIIGGKEQ GQPFQGQLSG LYYNGLKVLN MAAENDANIA 250
    IVGNVRLVGE VPSSMTTEST ATAMQSEMST SIMETTTTLA TSTARRGKPP 300
    TKEPISQTTD DILVASAECP SDDEDIDPCE PSSGGLANPT RVGGREPYPG 350
    SAEVIRESSS TTGMVVGIVA AAALCILILL YAMYKYRNRD EGSYHVDESR 400
    NYISNSAQSN GAVVKEKQPS SAKSANKNKK NKDKEYYV 438
    Length:438
    Mass (Da):46,660
    Last modified:November 16, 2011 - v1
    Checksum:i75DD733041D40A8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC101872 Genomic DNA. No translation available.
    AC131326 Genomic DNA. No translation available.
    AC151286 Genomic DNA. No translation available.
    AC154325 Genomic DNA. No translation available.
    AC154599 Genomic DNA. No translation available.
    AC167814 Genomic DNA. No translation available.
    AC170901 Genomic DNA. No translation available.
    AC171209 Genomic DNA. No translation available.
    CT025708 Genomic DNA. No translation available.
    CT486002 Genomic DNA. No translation available.
    RefSeqiXP_006523881.1. XM_006523818.1.
    UniGeneiMm.491332.

    Genome annotation databases

    EnsembliENSMUST00000174337; ENSMUSP00000133724; ENSMUSG00000024109.
    GeneIDi18189.
    KEGGimmu:18189.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC101872 Genomic DNA. No translation available.
    AC131326 Genomic DNA. No translation available.
    AC151286 Genomic DNA. No translation available.
    AC154325 Genomic DNA. No translation available.
    AC154599 Genomic DNA. No translation available.
    AC167814 Genomic DNA. No translation available.
    AC170901 Genomic DNA. No translation available.
    AC171209 Genomic DNA. No translation available.
    CT025708 Genomic DNA. No translation available.
    CT486002 Genomic DNA. No translation available.
    RefSeqi XP_006523881.1. XM_006523818.1.
    UniGenei Mm.491332.

    3D structure databases

    ProteinModelPortali G3UXK2.
    SMRi G3UXK2. Positions 84-259.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000174337 ; ENSMUSP00000133724 ; ENSMUSG00000024109 .
    GeneIDi 18189.
    KEGGi mmu:18189.

    Organism-specific databases

    CTDi 9378.
    MGIi MGI:1096391. Nrxn1.

    Phylogenomic databases

    GeneTreei ENSGT00750000117263.
    KOi K07377.

    Miscellaneous databases

    ChiTaRSi NRXN1. mouse.
    NextBioi 35560350.
    SOURCEi Search...

    Gene expression databases

    Bgeei G3UXK2.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001791. Laminin_G.
    IPR003585. Neurexin-like.
    IPR027789. Syndecan/Neurexin_dom.
    [Graphical view ]
    Pfami PF02210. Laminin_G_2. 1 hit.
    PF01034. Syndecan. 1 hit.
    [Graphical view ]
    SMARTi SM00294. 4.1m. 1 hit.
    SM00282. LamG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS50025. LAM_G_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG3UXK2_MOUSE
    AccessioniPrimary (citable) accession number: G3UXK2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3