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Protein
Submitted name:

Paired box protein Pax-7

Gene

Pax7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi217 – 276HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinPROSITE-ProRule annotationSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-7Imported
Gene namesi
Name:Pax7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:97491. Pax7.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiG3UX36.
PaxDbiG3UX36.
PRIDEiG3UX36.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028736.
ExpressionAtlasiG3UX36. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliG3UX36.
SMRiG3UX36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 163PairedInterPro annotationAdd BLAST130
Domaini215 – 275Homeobox DNA-bindingInterPro annotationAdd BLAST61
Domaini479 – 491OARInterPro annotationAdd BLAST13

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi479 – 491OARPROSITE-ProRule annotationAdd BLAST13

Sequence similaritiesi

Belongs to the paired homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation, Paired boxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0849. Eukaryota.
ENOG410XS01. LUCA.
GeneTreeiENSGT00680000099553.
OMAiMKLGDHS.
OrthoDBiEOG091G0S4E.

Family and domain databases

CDDicd00131. PAX. 1 hit.
Gene3Di1.10.10.10. 2 hits.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR003654. OAR_dom.
IPR001523. Paired_dom.
IPR022106. Pax7_C.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00292. PAX. 1 hit.
PF12360. Pax7. 1 hit.
PRINTSiPR00027. PAIREDBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00351. PAX. 1 hit.
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS50803. OAR. 1 hit.
PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3UX36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALPGAVPR MMRPGPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP
60 70 80 90 100
LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA
110 120 130 140 150
IGGSKPRQVA TPDVEKKIEE YKRENPGMFS WEIRDRLLKD GHCDRSTVPS
160 170 180 190 200
GLVSSISRVL RIKFGKKEDD EEGDKKEEDG EKKAKHSIDG ILGDKGNRLD
210 220 230 240 250
EGSDVESEPD LPLKRKQRRS RTTFTAEQLE ELEKAFERTH YPDIYTREEL
260 270 280 290 300
AQRTKLTEAR VQVWFSNRRA RWRKQAGANQ LAAFNHLLPG GFPPTGMPTL
310 320 330 340 350
PPYQLPDSTY PTTTISQDGG STVHRPQPLP PSTMHQGGLA AAAAAADTSS
360 370 380 390 400
AYGARHSFSS YSDSFMNPGA PSNHMNPVSN GLSPQVMSIL SNPSAVPPQP
410 420 430 440 450
QADFSISPLH GGLDSASSIS ASCSQRADSI KPGDSLPTSQ SYCPPTYSTT
460 470 480 490 500
GYSVDPVAGY QYSQYGQTAV DYLAKNVSLS TQRRMKLGEH SAVLGLLPVE

TGQAY
Length:505
Mass (Da):55,109
Last modified:November 16, 2011 - v1
Checksum:iFE0DD371B34C5039
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL831790 Genomic DNA. No translation available.
AL844480 Genomic DNA. No translation available.
RefSeqiXP_006538692.1. XM_006538629.1.
UniGeneiMm.218760.

Genome annotation databases

EnsembliENSMUST00000174681; ENSMUSP00000133536; ENSMUSG00000028736.
GeneIDi18509.

Similar proteinsi

Entry informationi

Entry nameiG3UX36_MOUSE
AccessioniPrimary (citable) accession number: G3UX36
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: August 30, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported