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Protein
Submitted name:

Neurexin-1

Gene

Nrxn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • acetylcholine receptor binding Source: MGI
  • calcium channel regulator activity Source: MGI

GO - Biological processi

  • adult behavior Source: MGI
  • learning Source: MGI
  • neurotransmitter secretion Source: MGI
  • positive regulation of synapse assembly Source: MGI
  • positive regulation of synapse maturation Source: MGI
  • regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
  • social behavior Source: MGI
  • synapse assembly Source: MGI
  • synaptic transmission Source: MGI
  • vesicle docking involved in exocytosis Source: MGI
  • vocalization behavior Source: MGI
  • vocal learning Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neurexin-1Imported
Gene namesi
Name:Nrxn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1096391. Nrxn1.

Subcellular locationi

GO - Cellular componenti

  • cell surface Source: MGI
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: MGI
  • presynaptic membrane Source: MGI
  • protein complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiG3UWQ9.
ExpressionAtlasiG3UWQ9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000125407.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Family and domain databases

InterProiIPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 1 hit.
PfamiPF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3UWQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMRWHCENS QTTDDILVAS AECPSDDEDI DPCEPSSGGL ANPTRVGGRE
60 70 80 90 100
PYPGSAEVIR ESSSTTGMVV GIVAAAALCI LILLYAMYKY RNRDEGSYHV
110 120 130 140
DESRNYISNS AQSNGAVVKE KQPSSAKSAN KNKKNKDKEY YV
Length:142
Mass (Da):15,516
Last modified:July 22, 2015 - v2
Checksum:i6E04FE50BFC0B43E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000173917; ENSMUSP00000133389; ENSMUSG00000024109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101872 Genomic DNA. No translation available.
AC131326 Genomic DNA. No translation available.
AC151286 Genomic DNA. No translation available.
AC154325 Genomic DNA. No translation available.
AC154599 Genomic DNA. No translation available.
AC167814 Genomic DNA. No translation available.
AC170901 Genomic DNA. No translation available.
AC171209 Genomic DNA. No translation available.
CT025708 Genomic DNA. No translation available.
CT486002 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000125407.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000173917; ENSMUSP00000133389; ENSMUSG00000024109.

Organism-specific databases

MGIiMGI:1096391. Nrxn1.

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Miscellaneous databases

ChiTaRSiNrxn1. mouse.
NextBioi35560110.
SOURCEiSearch...

Gene expression databases

BgeeiG3UWQ9.
ExpressionAtlasiG3UWQ9. baseline and differential.

Family and domain databases

InterProiIPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 1 hit.
PfamiPF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3UWQ9_MOUSE
AccessioniPrimary (citable) accession number: G3UWQ9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: July 22, 2015
Last modified: July 22, 2015
This is version 29 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.