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Protein
Submitted name:

Cytochrome P450 11B2, mitochondrial

Gene

Cyp11b2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-MMU-193993 Mineralocorticoid biosynthesis
R-MMU-194002 Glucocorticoid biosynthesis
R-MMU-211976 Endogenous sterols

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 11B2, mitochondrialImported
Submitted name:
MCG2779, isoform CRA_bImported
Gene namesi
Name:Cyp11b2Imported
ORF Names:mCG_2779Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:88584 Cyp11b2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000022589

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0159 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140779
KOiK00497
OMAiPFEAMPQ
OrthoDBiEOG091G0B8F
TreeFamiTF105094

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002399 Cyt_P450_mitochondrial
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00408 MITP450
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

G3UWE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMALRVTAD VWLARPWQCL HRTRALGTTA TLAPKTLQPF EAIPQYSRNK
60 70 80 90 100
WLKMIQILRE QGQENLHLEM HQVFRELGPI FRHSVGKTQI VSVMLPEDAE
110 120 130 140 150
KLHQVESMLP RRMHLEPWVA HRELRGLRRG VFLLNGPEWR LNRLRLNRNV
160 170 180 190 200
LSPKAVQKFV PMVDMVARDF LETLKEKVLQ NARGSLTMDV QQSLFNYTIE
210 220 230 240 250
ASNFALFGER LGLLGHDLSP GSLKFIHALH SMFKSTSQLL FLPKSLTRWT
260 270 280 290 300
STRVWKEHFD AWDVISEYAN RCIWKVHQEL RLGSSQTYSG IVAELISQGS
310 320 330 340 350
LPLDAIKANS MELTAGSVDT TAIPLVMTLF ELARNPDVQK ALRQESLAAE
360 370 380 390 400
ASIAANPQKA MSDLPLLRAA LKETLRLYPV GGFLERILSS DLVLQNYHVP
410 420 430 440 450
AGTLVLLYLY SMGRNPAVFP RPERYMPQRW LERKRSFQHL AFGFGVRQCL
460 470 480 490 500
GRRLAEVEMM LLLHHILKTF QVETLRQEDV QMAYRFVLMP SSSPVLTFRP

VS
Length:502
Mass (Da):57,575
Last modified:November 16, 2011 - v1
Checksum:iBCAFFF3EE471ED37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139671 Genomic DNA No translation available.
CH466545 Genomic DNA Translation: EDL29457.1
RefSeqiNP_034121.3, NM_009991.3
UniGeneiMm.377079

Genome annotation databases

EnsembliENSMUST00000167634; ENSMUSP00000131503; ENSMUSG00000022589
GeneIDi13072
KEGGimmu:13072
UCSCiuc007wgf.2 mouse

Similar proteinsi

Entry informationi

Entry nameiG3UWE4_MOUSE
AccessioniPrimary (citable) accession number: G3UWE4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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