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G3UW82

- G3UW82_MOUSE

UniProt

G3UW82 - G3UW82_MOUSE

Protein
Submitted name:

MCG140437, isoform CRA_d

Gene

Myh2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. motor activity Source: InterPro

    GO - Biological processi

    1. actin-mediated cell contraction Source: MGI
    2. plasma membrane repair Source: MGI
    3. response to activity Source: MGI

    Keywords - Molecular functioni

    Motor protein, MyosinSAAS annotation

    Keywords - Ligandi

    Actin-bindingSAAS annotation, ATP-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_198374. Regulation of actin dynamics for phagocytic cup formation.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MCG140437, isoform CRA_dImported
    Submitted name:
    Protein Myh2Imported
    Gene namesi
    Name:Myh2Imported
    ORF Names:mCG_140437Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1339710. Myh2.

    Subcellular locationi

    GO - Cellular componenti

    1. A band Source: MGI
    2. actomyosin contractile ring Source: MGI
    3. cell-cell junction Source: MGI
    4. focal adhesion Source: Ensembl
    5. Golgi apparatus Source: MGI
    6. muscle myosin complex Source: MGI
    7. myofibril Source: MGI
    8. nucleolus Source: Ensembl

    Family & Domainsi

    Sequence similaritiesi

    Contains IQ domain.SAAS annotation
    Contains myosin motor domain.SAAS annotation

    Keywords - Domaini

    Coiled coilSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00720000108596.
    KOiK10352.
    OMAiQITSNRK.
    OrthoDBiEOG7RBZ7G.
    TreeFamiTF314375.

    Family and domain databases

    Gene3Di4.10.270.10. 1 hit.
    InterProiIPR000048. IQ_motif_EF-hand-BS.
    IPR027401. Myosin-like_IQ_dom.
    IPR001609. Myosin_head_motor_dom.
    IPR004009. Myosin_N.
    IPR002928. Myosin_tail.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00063. Myosin_head. 1 hit.
    PF02736. Myosin_N. 1 hit.
    PF01576. Myosin_tail_1. 1 hit.
    [Graphical view]
    PRINTSiPR00193. MYOSINHEAVY.
    SMARTiSM00015. IQ. 2 hits.
    SM00242. MYSc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS50096. IQ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3UW82-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSDAEMAVF GEAAPYLRKS EKERIEAQNR PFDAKTSVFV AEPKESFVKG     50
    TIQSKDAGKV TVKTEAGATL TVKEDQIFPM NPPKYDKIED MAMMTHLHEP 100
    AVLYNLKERY AAWMIYTYSG LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE 150
    APPHIFSISD NAYQFMLTDR ENQSILITGE SGAGKTVNTK RVIQYFATIA 200
    VTGDKKKEEA TSGKMQGTLE DQIISANPLL EAFGNAKTVR NDNSSRFGKF 250
    IRIHFGTTGK LASADIETYL LEKSRVTFQL KAERSYHIFY QITSNKKPEL 300
    IEMLLITTNP YDYPFVSQGE ISVASIDDQE ELMATDSAID ILGFTNDEKV 350
    SIYKLTGAVM HYGNMKFKQK QREEQAEPDG TEVADKAAYL QGLNSADLLK 400
    ALCYPRVKVG NEYVTKGQTV EQVTNAVGAL AKAMYEKMFL WMVTRINQQL 450
    DTKQPRQYFI GVLDIAGFEI FDFNSLEQLC INFTNEKLQQ FFNHHMFVLE 500
    QEEYKKEGIE WTFIDFGMDL AACIELIEKP MGIFSILEEE CMFPKATDTS 550
    FKNKLYEQHL GKSANFQKPK VVKGKAEAHF SLIHYAGTVD YNITGWLDKN 600
    KDPLNETVVG LYQKSSVKTL AYLFSGAQTA EAEASSGGAA KKGAKKKGSS 650
    FQTVSALFRE NLNKLMTNLR STHPHFVRCI IPNETKTPGA MEHELVLHQL 700
    RCNGVLEGIR ICRKGFPSRI LYADFKQRYK VLNASAIPEG QYIDSKKASE 750
    KLLGSIDIDH TQYKFGHTKV FFKAGLLGLL EEMRDDKLAQ LITRTQAMCR 800
    GFLARVEYQK MVERRESIFC IQYNIRAFMN VKHWPWMKLF FKIKPLLKSA 850
    ETEKEMATMK EEFQKTKDDL AKSEAKRKEL EEKMVSLLKE KNDLQLQVQA 900
    EAEGLADAEE RCDQLIKTKI QLEAKIKEVT ERAEDEEEIN AELTAKKRKL 950
    EDECSELKKD IDDLELTLAK VEKEKHATEN KVKNLTEEMA GLDETIAKLT 1000
    KEKKALQEAH QQTLDDLQAE EDKVNTLTKA KIKLEQQVDD LEGSLEQEKK 1050
    LRMDLERAKR KLEGDLKLAQ ESIMDIENEK QQLDERLKKK EFEMSNLQSK 1100
    IEDEQAIGIQ LQKKIKELQA RIEELEEEIE AERASRAKAE KQRSDLSREL 1150
    EEISERLEEA GGATSAQIEM NKKREAEFQK MRRDLEEATL QHEATAATLR 1200
    KKHADSVAEL GEQIDNLQRV KQKLEKEKSE MKMEIDDLAS NVETVSKAKG 1250
    NLEKMCRTLE DQVSELKSKE EEQQRLINDL TTQRGRLQTE SGEFSRQLDE 1300
    KEALVSQLSR GKQAFTQQIE ELKRQLEEEV KAKNALAHAL QSSRHDCDLL 1350
    REQYEEEQES KAELQRALSK ANSEVAQWRT KYETDAIQRT EELEEAKKKL 1400
    AQRLQAAEEH VEAVNAKCAS LEKTKQRLQN EVEDLMLDVE RTNAACAALD 1450
    KKQRNFDKIL AEWKQKYEET HAELEASQKE ARSLGTELFK MKNAYEESLD 1500
    QLETLKRENK NLQQEISDLT EQIAEGGKRI HELEKIKKQV EQEKCELQAA 1550
    LEEAEASLEH EEGKILRIQL ELNQVKSEID RKIAEKDEEI DQLKRNHIRV 1600
    VESMQSTLDA EIRSRNDAIR IKKKMEGDLN EMEIQLNHSN RMAAEALRNY 1650
    RNTQGILKDT QLHLDDALRG QEDLKEQLAM VERRANLLQA EIEELRATLE 1700
    QTERSRKIAE QELLDASERV QLLHTQNTSL INTKKKLETD ISQIQGEMED 1750
    IVQEARNAEE KAKKAITDAA MMAEELKKEQ DTSAHLERMK KNMEQTVKDL 1800
    QLRLDEAEQL ALKGGKKQIQ KLEARVRELE GEVESEQKRN AEAVKGLRKH 1850
    ERRVKELTYQ TEEDRKNILR LQDLVDKLQA KVKSYKRQAE EAEEQSNTNL 1900
    SKFRKIQHEL EEAEERADIA ESQVNKLRVK SREVHTKIIS EE 1942
    Length:1,942
    Mass (Da):223,219
    Last modified:November 16, 2011 - v1
    Checksum:i9087D534CB3C4AD7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596129 Genomic DNA. No translation available.
    CH466601 Genomic DNA. Translation: EDL10428.1.
    RefSeqiNP_001034634.2. NM_001039545.2.
    XP_006532474.1. XM_006532411.1.
    UniGeneiMm.422801.

    Genome annotation databases

    EnsembliENSMUST00000018641; ENSMUSP00000018641; ENSMUSG00000033196.
    ENSMUST00000170159; ENSMUSP00000129544; ENSMUSG00000033196.
    GeneIDi17882.
    KEGGimmu:17882.
    UCSCiuc007jmd.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596129 Genomic DNA. No translation available.
    CH466601 Genomic DNA. Translation: EDL10428.1 .
    RefSeqi NP_001034634.2. NM_001039545.2.
    XP_006532474.1. XM_006532411.1.
    UniGenei Mm.422801.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000018641 ; ENSMUSP00000018641 ; ENSMUSG00000033196 .
    ENSMUST00000170159 ; ENSMUSP00000129544 ; ENSMUSG00000033196 .
    GeneIDi 17882.
    KEGGi mmu:17882.
    UCSCi uc007jmd.2. mouse.

    Organism-specific databases

    CTDi 4620.
    MGIi MGI:1339710. Myh2.

    Phylogenomic databases

    GeneTreei ENSGT00720000108596.
    KOi K10352.
    OMAi QITSNRK.
    OrthoDBi EOG7RBZ7G.
    TreeFami TF314375.

    Enzyme and pathway databases

    Reactomei REACT_198374. Regulation of actin dynamics for phagocytic cup formation.

    Miscellaneous databases

    NextBioi 292681.
    PROi G3UW82.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 4.10.270.10. 1 hit.
    InterProi IPR000048. IQ_motif_EF-hand-BS.
    IPR027401. Myosin-like_IQ_dom.
    IPR001609. Myosin_head_motor_dom.
    IPR004009. Myosin_N.
    IPR002928. Myosin_tail.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00063. Myosin_head. 1 hit.
    PF02736. Myosin_N. 1 hit.
    PF01576. Myosin_tail_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00193. MYOSINHEAVY.
    SMARTi SM00015. IQ. 2 hits.
    SM00242. MYSc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS50096. IQ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    5. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG3UW82_MOUSE
    AccessioniPrimary (citable) accession number: G3UW82
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3