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Protein
Submitted name:

Hexokinase 1, isoform CRA_f

Gene

Hk1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 1, isoform CRA_fImported
Submitted name:
Hexokinase-1Imported
Gene namesi
Name:Hk1Imported
ORF Names:mCG_127656Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:96103. Hk1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000037012.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000072195.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 218198Hexokinase_1InterPro annotationAdd
BLAST
Domaini224 – 458235Hexokinase_2InterPro annotationAdd
BLAST
Domaini469 – 666198Hexokinase_1InterPro annotationAdd
BLAST
Domaini672 – 906235Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3UVV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSEHCPSVP CGGAGAWEAR IDKYLYAMRL SDEILIDILT RFKKEMKNGL
60 70 80 90 100
SRDYNPTASV KMLPTFVRSI PDGSEKGDFI ALDLGGSSFR ILRVQVNHEK
110 120 130 140 150
SQNVSMESEV YDTPENIVHG SGSQLFDHVA ECLGDFMEKR KIKDKKLPVG
160 170 180 190 200
FTFSFPCRQS KIDEAVLITW TKRFKASGVE GADVVKLLNK AIKKRGDYDA
210 220 230 240 250
NIVAVVNDTV GTMMTCGYDD QQCEVGLIIG TGTNACYMEE LRHIDLVEGD
260 270 280 290 300
EGRMCINTEW GAFGDDGSLE DIRTEFDREL DRGSLNPGKQ LFEKMVSGMY
310 320 330 340 350
MGELVRLILV KMAKESLLFE GRITPELLTR GKFTTSDVAA IETDKEGVQN
360 370 380 390 400
AKEILTRLGV EPSHDDCVSV QHVCTIVSFR SANLVAATLG AILNRLRDNK
410 420 430 440 450
GTPRLRTTVG VDGSLYKMHP QYSRRFHKTL RRLVPDSDVR FLLSESGSGK
460 470 480 490 500
GAAMVTAVAY RLAEQHRQIE ETLSHFRLSK QALMEVKKKL RSEMEMGLRK
510 520 530 540 550
ETNSRATVKM LPSYVRSIPD GTEHGDFLAL DLGGTNFRVL LVKIRSGKKR
560 570 580 590 600
TVEMHNKIYS IPLEIMQGTG DELFDHIVSC ISDFLDYMGI KGPRMPLGFT
610 620 630 640 650
FSFPCKQTSL DCGILITWTK GFKATDCVGH DVATLLRDAV KRREEFDLDV
660 670 680 690 700
VAVVNDTVGT MMTCAYEEPS CEIGLIVGTG SNACYMEEMK NVEMVEGNQG
710 720 730 740 750
QMCINMEWGA FGDNGCLDDI RTDFDKVVDE YSLNSGKQRF EKMISGMYLG
760 770 780 790 800
EIVRNILIDF TKKGFLFRGQ ISEPLKTRGI FETKFLSQIE SDRLALLQVR
810 820 830 840 850
AILQQLGLNS TCDDSILVKT VCGVVSKRAA QLCGAGMAAV VEKIRENRGL
860 870 880 890 900
DHLNVTVGVD GTLYKLHPHF SRIMHQTVKE LSPKCTVSFL LSEDGSGKGA
910
ALITAVGVRL RGDPTNA
Length:917
Mass (Da):101,873
Last modified:November 16, 2011 - v1
Checksum:i65E6B23EED3B2ED7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126428 Genomic DNA. No translation available.
AC145297 Genomic DNA. No translation available.
CH466553 Genomic DNA. Translation: EDL32108.1.
RefSeqiXP_006513309.1. XM_006513246.2.
UniGeneiMm.196605.

Genome annotation databases

EnsembliENSMUST00000130422; ENSMUSP00000118601; ENSMUSG00000037012.
GeneIDi15275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126428 Genomic DNA. No translation available.
AC145297 Genomic DNA. No translation available.
CH466553 Genomic DNA. Translation: EDL32108.1.
RefSeqiXP_006513309.1. XM_006513246.2.
UniGeneiMm.196605.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000072195.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000130422; ENSMUSP00000118601; ENSMUSG00000037012.
GeneIDi15275.

Organism-specific databases

CTDi3098.
MGIiMGI:96103. Hk1.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037012.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG3UVV4_MOUSE
AccessioniPrimary (citable) accession number: G3UVV4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 7, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.