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Protein
Submitted name:

5-hydroxytryptamine (Serotonin) receptor 2B, isoform CRA_b

Gene

Htr2b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine (Serotonin) receptor 2B, isoform CRA_bImported
Submitted name:
5-hydroxytryptamine receptor 2BImported
Gene namesi
Name:Htr2bImported
ORF Names:mCG_8510Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:109323 Htr2b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 46HelicalSequence analysisAdd BLAST27
Transmembranei58 – 80HelicalSequence analysisAdd BLAST23
Transmembranei101 – 121HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000026228

Structurei

3D structure databases

SMRiG3UVT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 173G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST173

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00890000139331

Family and domain databases

InterProiView protein in InterPro
IPR000482 5HT2B_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR24247:SF31 PTHR24247:SF31, 2 hits
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

G3UVT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NILVILAVAL EKRLQYATNY FLMSLAIADL LVGLFVMPIA LLTIMFEAIW
60 70 80 90 100
PLPLALCPAW LFLDVLFSTA SIMHLCAISL DRYIAIKKPI QANQCNSRAT
110 120 130 140 150
AFIKITVVWL ISIGMWGMPL FPYGQNASSG IAIPVPIKGI ETDVINPHNV
160 170
TCELTKDRFG SFMVFGSLAA FFA
Length:173
Mass (Da):19,069
Last modified:November 16, 2011 - v1
Checksum:i50FF0155366D17CD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei173Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157768 Genomic DNA No translation available.
CH466520 Genomic DNA Translation: EDL40239.1
UniGeneiMm.439747

Genome annotation databases

EnsembliENSMUST00000155077; ENSMUSP00000116273; ENSMUSG00000026228

Similar proteinsi

Entry informationi

Entry nameiG3UVT8_MOUSE
AccessioniPrimary (citable) accession number: G3UVT8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 25, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported