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Protein

Eukaryotic translation initiation factor 6

Gene

EIF6

Organism
Meleagris gallopavo (Wild turkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorUniRule annotation
Biological processProtein biosynthesis, Ribosome biogenesisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 6UniRule annotation
Short name:
eIF-6UniRule annotation
Gene namesi
Name:EIF6UniRule annotationImported
OrganismiMeleagris gallopavo (Wild turkey)Imported
Taxonomic identifieri9103 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaeMeleagridinaeMeleagris
Proteomesi
  • UP000001645 Componenti: Chromosome 22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation

Interactioni

Subunit structurei

Monomer. Associates with the 60S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi9103.ENSMGAP00000017783.

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3185. Eukaryota.
COG1976. LUCA.
GeneTreeiENSGT00390000015972.
KOiK03264.
OMAiNDWCAFT.
TreeFamiTF105396.

Family and domain databases

CDDicd00527. IF6. 1 hit.
HAMAPiMF_00032. eIF_6. 1 hit.
InterProiView protein in InterPro
IPR002769. eIF6.
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiView protein in Pfam
PF01912. eIF-6. 1 hit.
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiView protein in SMART
SM00654. eIF6. 1 hit.
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

G3UQA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRASFENN NELGCFAKLT NAYCLVAIGG SENFYSVFEG ELFGTIPVVH
60 70 80 90 100
ASIAGCRIIG RMCVGNRHGL LVPSSTTDQE LQHIRNSLPD SVRIQRVEER
110 120 130 140 150
LSALGNVTTC NDYVALVHPD LDRETEEILA DVLKVEVFRQ TVADQVLVGS
160 170 180 190 200
YCVFSNQGGI VHPKTSIEDQ DELSSLLQVP LVAGTVNRGS EVIGAGMVVN
210 220 230 240
DWCAFCGLDT TSTELSVIES IFKLNEAQPS TIATNMRDSL IDSLA
Length:245
Mass (Da):26,525
Last modified:November 16, 2011 - v1
Checksum:iCDD4D00E3FE34821
GO

Sequence databases

RefSeqiXP_003211945.1. XM_003211897.3.

Genome annotation databases

EnsembliENSMGAT00000020658; ENSMGAP00000017783; ENSMGAG00000001965.
GeneIDi100550619.
KEGGimgp:100550619.

Similar proteinsi

Entry informationi

Entry nameiG3UQA9_MELGA
AccessioniPrimary (citable) accession number: G3UQA9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported