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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Loxodonta africana (African elephant)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi595 – 674Nuclear receptorPROSITE-ProRule annotationAdd BLAST80

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiLoxodonta africana (African elephant)Imported
Taxonomic identifieri9785 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeLoxodonta
Proteomesi
  • UP000007646 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9785.ENSLAFP00000017164.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini595 – 674Nuclear receptorInterPro annotationAdd BLAST80

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118887.
InParanoidiG3TP82.
OMAiSKICLVC.
OrthoDBiEOG091G0166.
TreeFamiTF106510.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3TP82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHNHP EDLDMERRWG QISQAVEHSS LGPTERTDEN KYMDIVNVSC
60 70 80 90 100
VSGAIPNNST QGSSKEKHEL LPCLQQDNNR SGILTSDIKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SIRDADYTYD QQNQQGSMSP AKIYQNVEQL MKFYKENGHR
160 170 180 190 200
PSMLNSVSRP LRSFMSDPMS CVNGGVMRAI VKSPITCHEK SPSVCSPLNM
210 220 230 240 250
ASSGCSPSGI NSVSSTTASF GSFAVHSPIT GTPLTCSPNV ENRGSRSHSP
260 270 280 290 300
AHASNVGSPL SSPLSSMKSP ISSPPSHCSV KSPVSSPNVT LRSSVSSPGN
310 320 330 340 350
INNSRCSVSS PSNTNNRSTL SSPTVGSICS PANSAFSYAA SGTPVGSIAT
360 370 380 390 400
RDMIPSPDTH EKGAPEVPFP KTEEIENAIS NGVTGQLNIV QYIKPEPDGA
410 420 430 440 450
FSSSCLGGNS KINSDSQFSV PIKQESTKHS CSGTSFKGNP PVNPFPFMDG
460 470 480 490 500
SYFSFMDDKD YYSLSGILGP PVPGFDGSCE GGGFSMGIKQ EPDDGSYYPE
510 520 530 540 550
TSMPSSAVVG VNSGGQSFHY RIGAQGTISL SRSARDQSFQ HLSSFPPVST
560 570 580 590 600
LVESWKSHGD LPSRRSDGYP VLEYIPENVS SSTLRSVSTG SSRPSKICLV
610 620 630 640 650
CGDEASGCHY GVVTCGSCKV FFKRAVEGKC SWQHNYLCAG RNDCIIDKIR
660 670 680 690 700
RKNCPACRLQ KCLQAGMNLG ARKSKKLGKL KGIHEEQPQQ QQALPPPPPP
710 720 730 740 750
QSPEEGTTYI APMKEPSVNT ALVPQLSTLS RALTPTPAMI LENIEPEIVY
760 770 780 790 800
AGYDSSKPDT AENLLSTLNR LAGKQMIQVV KWAKVLPGFK NLPLEDQITL
810 820 830 840 850
IQYSWMCLSS FALSWRSYKH TNSQYLYFAP DLVFNEEKMH QSAMYELCQG
860 870 880 890 900
MHQVSLQFVR LQLTFEEYTI MKVLLLLSTI PKDGLKSQAA FEEMRANYIK
910 920 930 940 950
ELRKMVTKCP NNSGQSWQRF YQLTKLLDSM HDLVSDLLEF CFYTFRESQA
960 970 980
LKVEFPAMLV EIISDQLPKV ESGNAKPLYF HRK
Length:983
Mass (Da):107,437
Last modified:November 16, 2011 - v1
Checksum:i46300A3F5F0E346F
GO

Genome annotation databases

EnsembliENSLAFT00000022551; ENSLAFP00000017164; ENSLAFG00000022550.

Similar proteinsi

Entry informationi

Entry nameiG3TP82_LOXAF
AccessioniPrimary (citable) accession number: G3TP82
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 22, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported