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Protein
Submitted name:

TNF receptor superfamily member 21

Gene

TNFRSF21

Organism
Loxodonta africana (African elephant)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor superfamily member 21Imported
Gene namesi
Name:TNFRSF21Imported
OrganismiLoxodonta africana (African elephant)Imported
Taxonomic identifieri9785 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeLoxodonta
Proteomesi
  • UP000007646 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi92 ↔ 107PROSITE-ProRule annotation
Disulfide bondi114 ↔ 132PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Interactioni

Protein-protein interaction databases

STRINGi9785.ENSLAFP00000013375.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 132TNFR-CysInterPro annotationAdd BLAST42
Repeati91 – 132TNFR-CysPROSITE-ProRule annotationAdd BLAST42
Domaini417 – 500DeathInterPro annotationAdd BLAST84

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHQ6. Eukaryota.
ENOG410YYKW. LUCA.
GeneTreeiENSGT00760000119204.
InParanoidiG3TG11.
KOiK05157.
OMAiLMEDTAQ.
OrthoDBiEOG091G03XW.
TreeFamiTF331157.

Family and domain databases

CDDicd08778. Death_TNFRSF21. 1 hit.
cd10583. TNFRSF21. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022330. TNFR_21.
IPR034037. TNFRSF21_death.
IPR034034. TNFRSF21_N.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 3 hits.
PRINTSiPR01971. TNFACTORR21.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM01411. Ephrin_rec_like. 2 hits.
SM00208. TNFR. 4 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3TG11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSSASSSTA SLASCSRIVG GAGATMIAGS LLLLGFLSTT TAQPEQKAPN
60 70 80 90 100
LIGTYRHVDR ATGQVLTCDK CPAGTYVSEH CTSTSLRVCS SCPMGTFTRH
110 120 130 140 150
ENGIEKCHDC SQPCPWPMIE KLPCAALTDR ECTCPPGMFQ SNATCAPHTV
160 170 180 190 200
CPVGWGVRKK GTEMEDVRCK QCARGTFSDV PSSVMKCKAY TDCLSQNLVV
210 220 230 240 250
IKPGTKEADN VCGALPSFSS TTPPSPGTAI VSRPEHMESH EVLSSTYVPK
260 270 280 290 300
GMNSTESNSS ASVRPKVPSG IQEGTVPDNT SSARGEEGEN KTLSNFQVIN
310 320 330 340 350
HQQGPHHRHI LKLLPSSMEA TEGEKSSTPI KVPKRGHPRQ TLHKHFDINE
360 370 380 390 400
HLPWMIVLFL LLVLVVIVVC SIRKSSRTLK KGPRQDPSAI VEKAGLKKSV
410 420 430 440 450
TPTQNREKWI YYCNGHGIDI LKLVAAQVGS QWKDIYQFLC NASEREVAAF
460 470 480 490 500
SNGYTADHER AYAALQHWTI RGPEASLAQL ISALRQHRRN DVVEKIRGLM
510 520 530 540 550
EDTAQLETDK LALPTSPGPL SPSPIPSPNG KLENSTLLTV EPSPLDKNKG
560 570 580 590 600
FFVDESEPLL RCDSTSSGSS ALSRNGSFIT KEKKDTVLRQ VRLDPCDLQP
610 620 630 640 650
IFDDMLHILN PEELRVIEEI PQAEDKLDRL FEIIGVKSQE ASQTLLDSVY

SHLPDLL
Length:657
Mass (Da):71,629
Last modified:November 16, 2011 - v1
Checksum:i18991C356CA06B29
GO

Sequence databases

RefSeqiXP_003404497.1. XM_003404449.2.

Genome annotation databases

EnsembliENSLAFT00000015947; ENSLAFP00000013375; ENSLAFG00000015950.
GeneIDi100675615.
KEGGilav:100675615.

Similar proteinsi

Entry informationi

Entry nameiG3TG11_LOXAF
AccessioniPrimary (citable) accession number: G3TG11
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: August 30, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported