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Protein
Submitted name:

5-hydroxytryptamine receptor 4

Gene

HTR4

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine receptor 4Imported
Gene namesi
Name:HTR4Imported
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 45HelicalSequence analysisAdd BLAST26
Transmembranei57 – 79HelicalSequence analysisAdd BLAST23
Transmembranei99 – 117HelicalSequence analysisAdd BLAST19
Transmembranei138 – 158HelicalSequence analysisAdd BLAST21
Transmembranei192 – 213HelicalSequence analysisAdd BLAST22
Transmembranei260 – 281HelicalSequence analysisAdd BLAST22
Transmembranei293 – 315HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGGOG00000016400.

Interactioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000017366.

Structurei

3D structure databases

ProteinModelPortaliG3RNJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 312G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST277

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00890000139340.
InParanoidiG3RNJ9.
OMAiWIYGETF.
OrthoDBiEOG091G06VI.
TreeFamiTF316350.

Family and domain databases

CDDicd15056. 7tmA_5-HT4. 1 hit.
InterProiView protein in InterPro
IPR001520. 5HT4_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01059. 5HT4RECEPTR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3RNJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL
60 70 80 90 100
RKIKTNYFIV SLAFADLLVS VLVMPFGAIE LVQDIWIYGE MFCLVRTSLD
110 120 130 140 150
VLLTTASIFH LCCISLDRYY AICCQPLVYR NKMTPLRIAL MLGGCWVIPT
160 170 180 190 200
FISFLPIMQG WNNIGIIDLI EKRKFNQNSN STYCVFMVNK PYAITCSVVA
210 220 230 240 250
FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP QSADQHSTHR
260 270 280 290 300
MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
310 320 330 340 350
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT
360 370 380 390 400
INGSTHVLRT DFLFDRDILA RYWTKPARAG PFSGTLSIRC LTARKPVLGD
410 420
AVECGGQWES QCHPPATSPL VAAQPSDT
Length:428
Mass (Da):48,287
Last modified:November 16, 2011 - v1
Checksum:iC4C80A51848D3798
GO

Sequence databases

RefSeqiXP_004042828.1. XM_004042780.2.

Genome annotation databases

EnsembliENSGGOT00000029319; ENSGGOP00000017366; ENSGGOG00000016400.
GeneIDi101142127.

Similar proteinsi

Entry informationi

Entry nameiG3RNJ9_GORGO
AccessioniPrimary (citable) accession number: G3RNJ9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 25, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported