GPT2

Functionⁱ

GO - Molecular functionⁱ

L-alanine:2-oxoglutarate aminotransferase activity Source: Ensembl
pyridoxal phosphate binding Source: InterPro

GO - Biological processⁱ

2-oxoglutarate metabolic process Source: Ensembl
biosynthetic process Source: InterPro
L-alanine metabolic process Source: Ensembl

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Glutamic--pyruvic transaminase 2Imported
Gene namesⁱ	Name:GPT2Imported
Organismⁱ	Gorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifierⁱ	9595 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Gorilla › Gorilla gorilla
Proteomesⁱ	UP000001519 Componentⁱ: Chromosome 16

Subcellular locationⁱ

GO - Cellular componentⁱ

mitochondrion Source: Ensembl

Complete GO annotation...

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSGGOG00000016287.

Bgeeⁱ

ENSGGOG00000016287.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9593.ENSGGOP00000015896.

STRINGⁱ

9593.ENSGGOP00000015896.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	G3RJK4.
SMRⁱ	G3RJK4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	111 – 510	Aminotran_1_2InterPro annotationAdd BLAST		400

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00650000093331.
InParanoidⁱ	G3RJK4.
KEGG Orthology (KO) More...KOⁱ	K00814.
OMAⁱ	VQGAMYV.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0PY3.
TreeFamⁱ	TF300839.

Family and domain databases

Gene3Dⁱ	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterProⁱ	View protein in InterPro IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_sub2.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00155. Aminotran_1_2. 1 hit.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

G3RJK4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MQRAAALVRR GCGPRTPSSW GRSQSSAAAE ASAVLKVRPE RSRRERILTL 
        60         70         80         90        100
ESMNPQVKAV EYAVRGPIVL KAGEIELELQ RGIKKPFTEV IRANIGDAQA 
       110        120        130        140        150
MGQQPITFLR QVMALCTYPN LLDSPSFPED AKKRARRILQ ACGGNSLGSY 
       160        170        180        190        200
SASQGVNCIR EDVAAYITRR DGGVPADPDN IYLTTGASDG ISTILKILVS 
       210        220        230        240        250
GGGKSRTGVM IPIPQYPLYS AVISELDAIQ VNYYLDEENC WALNVNELRR 
       260        270        280        290        300
AVQEAKDHCD PKVLCIINPG NPTGQVQSRK CIEDVIHFAW EEKLFLLADE 
       310        320        330        340        350
VYQDNVYSPD CRFHSFKKVL YEMGPEYSSN VELASFHSTS KGYMGECGYR 
       360        370        380        390        400
GGYMEVINLH PEIKGQLVKL LSVRLCPPVS GQAAMDIVVN PPVAGEESFE 
       410        420        430        440        450
QFSREKESVL GNLAKKAKLT EDLFNQVPGI HCNPLQGAMY AFPRIFIPAK 
       460        470        480        490        500
AVEAAQAHQM APDMFYCMKL LEETGICVVP GSGFGQREGT YHFRMTILPP 
       510        520 
VEKLKTVLQK VKDFHINFLE KYA

Length:523

Mass (Da):57,904

Last modified:November 16, 2011 - v1

Checksum:ⁱ4DD87814C62C7DEA

GO

Sequence databases

NCBI Reference Sequences More...RefSeqⁱ	XP_004057650.1. XM_004057602.2.

RefSeqⁱ

XP_004057650.1. XM_004057602.2.

Genome annotation databases

Ensemblⁱ	ENSGGOT00000016349; ENSGGOP00000015896; ENSGGOG00000016287.
GeneIDⁱ	101142979.
KEGGⁱ	ggo:101142979.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
G3RJK4	Q8TD30 A0A024R6R2 UPI0001D6079B H2NQT3 Q8TD30-2 B3KR40	Homo sapiens (Human) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	523	UniRef100_Q8TD30	Cluster: Alanine aminotransferase 2	7

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
G3RJK4	Q8TD30 A0A024R6R2 UPI0001D6079B H2NQT3 Q8TD30-2 B3KR40 A0A096NI27 G7NP87 UPI0000D9F10C F7FK03 +105	Homo sapiens (Human) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Papio anubis (Olive baboon) Macaca mulatta (Rhesus macaque) Colobus angolensis palliatus (Peters' Angolan colobus) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Camelus dromedarius (Dromedary) (Arabian camel) And more	523	UniRef90_Q8TD30	Cluster: Alanine aminotransferase 2	116

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
G3RJK4	Q8TD30 A0A024R6R2 UPI0001D6079B H2NQT3 Q8TD30-2 B3KR40 UPI00045DAF15 UPI0003AB84EE UPI0005F56470 UPI0005F3F5E0 +337	Homo sapiens (Human) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Colobus angolensis palliatus (Peters' Angolan colobus) Papio anubis (Olive baboon) Macaca mulatta (Rhesus macaque) Camelus dromedarius (Dromedary) (Arabian camel) And more	523	UniRef50_Q8TD30	Cluster: Alanine aminotransferase 2	348

Cross-referencesⁱ

Sequence databases

NCBI Reference Sequences More...RefSeqⁱ	XP_004057650.1. XM_004057602.2.

RefSeqⁱ

XP_004057650.1. XM_004057602.2.

3D structure databases

ProteinModelPortalⁱ	G3RJK4.
SMRⁱ	G3RJK4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9593.ENSGGOP00000015896.

STRINGⁱ

9593.ENSGGOP00000015896.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSGGOT00000016349; ENSGGOP00000015896; ENSGGOG00000016287.
GeneIDⁱ	101142979.
KEGGⁱ	ggo:101142979.

Organism-specific databases

CTDⁱ	84706.

CTDⁱ

84706.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00650000093331.
InParanoidⁱ	G3RJK4.
KEGG Orthology (KO) More...KOⁱ	K00814.
OMAⁱ	VQGAMYV.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0PY3.
TreeFamⁱ	TF300839.

Gene expression databases

Bgeeⁱ	ENSGGOG00000016287.

Bgeeⁱ

ENSGGOG00000016287.

Family and domain databases

Gene3Dⁱ	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterProⁱ	View protein in InterPro IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_sub2.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00155. Aminotran_1_2. 1 hit.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	G3RJK4_GORGO
Accessionⁱ	G3RJK4Primary (citable) accession number: G3RJK4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 16, 2011
	Last sequence update:	November 16, 2011
	Last modified:	August 30, 2017
	This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - G3RJK4 (G3RJK4_GORGO)

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Glutamic--pyruvic transaminase 2

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - G3RJK4 (G3RJK4_GORGO)

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Glutamic--pyruvic transaminase 2

GPT2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ