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Protein

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Gene

NDUFA12

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12UniRule annotation
Gene namesi
Name:NDUFA12Imported
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Expressioni

Gene expression databases

BgeeiENSGGOG00000012880.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA12 subunit family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000005848.
OMAiWHGWIHH.
OrthoDBiEOG091G0XDC.
TreeFamiTF106106.

Family and domain databases

InterProiView protein in InterPro
IPR007763. NDUFA12.
PANTHERiPTHR12910. PTHR12910. 1 hit.
PfamiView protein in Pfam
PF05071. NDUFA12. 1 hit.

Sequencei

Sequence statusi: Complete.

G3RAT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QRGKMELVQV LKRGLQQITG HGGLRGYLRV FFRTNDAKVG TLVGEDKYGN
60 70 80 90 100
KYYEDNKQFF GRHRWVVYTT EMNGKNTFWD VDGSMVPPEW HRWLHSMTDD
110 120 130 140
PPTTKPLTAR KFIWTNHKFN MTGTPEQYVP YSTTRKKIQE WIPPSTPYK
Length:149
Mass (Da):17,616
Last modified:November 16, 2011 - v1
Checksum:i9181D74EBA56D2D3
GO

Genome annotation databases

EnsembliENSGGOT00000012924; ENSGGOP00000012562; ENSGGOG00000012880.

Similar proteinsi

Entry informationi

Entry nameiG3RAT4_GORGO
AccessioniPrimary (citable) accession number: G3RAT4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 7, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported