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G2Z379

- G2Z379_FLABF

UniProt

G2Z379 - G2Z379_FLABF

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Protein

Thymidine kinase

Gene

tdk

Organism
Flavobacterium branchiophilum (strain FL-15)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATPUniRule annotation
Nucleotide bindingi93 – 964ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciFBRA1034807:GHGD-35-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:FBFL15_0035Imported
OrganismiFlavobacterium branchiophilum (strain FL-15)Imported
Taxonomic identifieri1034807 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
ProteomesiUP000009186: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiDHISEST.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

G2Z379-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAQF AKQKVEIFKP
60 70 80 90 100
AIDTRYDNEM VVSHDSNEIR STPVPAAANI AILAQGCDVV GIDEAQFFDD
110 120 130 140 150
EIVKICNDLA NNGIRVIVAG LDMDFKGNPF GPMPALMATA EYVTKVHAVC
160 170 180 190
TRTGNLAHYS FRKKANDNLV MLGETNEYEP LSRAAFFNAM PLKK
Length:194
Mass (Da):21,679
Last modified:November 16, 2011 - v1
Checksum:iE8EE75E22D1BC9AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ859183 Genomic DNA. Translation: CCB68192.1.
RefSeqiYP_004842429.1. NC_016001.1.

Genome annotation databases

EnsemblBacteriaiCCB68192; CCB68192; FBFL15_0035.
GeneIDi11151492.
KEGGifbr:FBFL15_0035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ859183 Genomic DNA. Translation: CCB68192.1 .
RefSeqi YP_004842429.1. NC_016001.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCB68192 ; CCB68192 ; FBFL15_0035 .
GeneIDi 11151492.
KEGGi fbr:FBFL15_0035.

Phylogenomic databases

KOi K00857.
OMAi DHISEST.

Enzyme and pathway databases

BioCyci FBRA1034807:GHGD-35-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FL-15Imported.

Entry informationi

Entry nameiG2Z379_FLABF
AccessioniPrimary (citable) accession number: G2Z379
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3