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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bacillus coagulans 36D1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei150 – 1501UniRule annotation
Active sitei575 – 5751UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBCOA345219:GH5A-652-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:Bcoa_0655Imported
OrganismiBacillus coagulans 36D1Imported
Taxonomic identifieri345219 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000009283 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2TQM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQIDEKKAP RMALQADMDF LAGLLDKVIL FEGGEALLKT IQNIRSLAQK
60 70 80 90 100
ARETGDEAFY LQLKKEITDL NPPERQEVIR AFSTYLQLFN ITEQNFRIKR
110 120 130 140 150
RREYQSEDTD QVQPRSLEDG IETLRKEKVP AEMVAELLNS LSLELIITAH
160 170 180 190 200
PTEATRRTIL QIHKRIADLL KALEYANTRY EKKVIEETIL NEITILWQSS
210 220 230 240 250
EIREKKPSVL DEVKNGLYYF DNVLFDVLPR IHEDLEDYLH ESYGQRFKVP
260 270 280 290 300
SYLHFGSWIG GDRDGNPNVT ADITWKTLEM QRELVLEKYK KSLTTLRELL
310 320 330 340 350
SHSSKKISAS HALLASVESE ENTMPAAKLW PTKDEIYRRK LTIMIHKLEC
360 370 380 390 400
VGKNNGGYQS AKELLADLYM IRDSVNQHHP AGHPIKLLRK VIRQVELFGF
410 420 430 440 450
HLASLDIRNH SGEHESALAE VLYNVNIAKD YKNLSEDEKV AVLLKALNDP
460 470 480 490 500
RPMISIYDTF TPETQEVINT FRMIKRAHQT FGERSIQVYL ISMAHSVSDV
510 520 530 540 550
LEVLVLAKEA GLYRVYPSGD ILSEIHIAPL LETIADLRNG AKMLETLFQM
560 570 580 590 600
PIYRNHLKVR GNLQEVMLGY SDGSKDGGTM TANWQLYKAQ KEIHEMGAKY
610 620 630 640 650
GIKLKFFHGR GGSLGRGGGP LYSSLLSQPP VTLGDGVKIT EQGEVLSSRY
660 670 680 690 700
LLRDIAYRSL EQATSTMMCA ITEQKQNEKN GKTPNEEAVR AMDKISEYAL
710 720 730 740 750
EKYQELVFRD PDFLSYFKQA TPLNEIGELN IGSRPMSRKG SARFEDLRAI
760 770 780 790 800
PWVFSWTQSR QLLPAWYAAG TGLSKYVEET GNFKLLQEMY ASWPFFHATI
810 820 830 840 850
NNLQMALIKA ELSTAEEYTR LVKDPEVAGR IFGLIKAEYE LTKEMVLKIA
860 870 880 890 900
DQKELLDYTP NIKESVRLRN PYVDPLNLFQ VYLISQLRER ENKDEKARHL
910
LMEVLLTING IAAGLRNTG
Length:919
Mass (Da):105,199
Last modified:November 15, 2011 - v1
Checksum:iB28AF068D59DFDA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003056 Genomic DNA. Translation: AEO99874.1.
RefSeqiYP_004858655.1. NC_016023.1.

Genome annotation databases

EnsemblBacteriaiAEO99874; AEO99874; Bcoa_0655.
KEGGibag:Bcoa_0655.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003056 Genomic DNA. Translation: AEO99874.1.
RefSeqiYP_004858655.1. NC_016023.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEO99874; AEO99874; Bcoa_0655.
KEGGibag:Bcoa_0655.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciBCOA345219:GH5A-652-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 36D1Imported.

Entry informationi

Entry nameiG2TQM6_BACCO
AccessioniPrimary (citable) accession number: G2TQM6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 15, 2011
Last sequence update: November 15, 2011
Last modified: March 31, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.