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G2T5Z4 (G2T5Z4_ROSHA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608
Gene names
Ordered Locus Names:RHOM_15980 EMBL AEN98302.1
OrganismRoseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183) [Complete proteome] [HAMAP]
Taxonomic identifier585394 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Lachnospiraceae › Roseburia ›

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
   LigandPyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
   Molecular functionIsomerase RuleBase RU000608 SAAS SAAS020622
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionalanine racemase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
G2T5Z4 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 98F8125DF2D51C07

FASTA38942,862
        10         20         30         40         50         60 
MESTLRRTWA EIDLDALAHN YHKLRERIGA DVKFLGVVKA DAYGHGSVQV SHLLQELGAD 

        70         80         90        100        110        120 
YLAVSSIDEA VELRLNDVTM PILILGHTPK EQVSRLIKYH ITQAVSCEAK ALEYSEEAVK 

       130        140        150        160        170        180 
CGGILKIHIK VDTGMSRLGY LCDGDHFETG VAGICHGCSL PGLDAEGIFT HFAVSDEPGE 

       190        200        210        220        230        240 
DCKKYTEHQF DLFMRVIEEV EKRLGRKFAL RHCANTGAVA RYPETFLDMV RPGLLLYGYG 

       250        260        270        280        290        300 
EFADELGLLP VMTLKTTVST IKIYPAGTAI SYGGIFKTEH TTRIGVVPYG YADGFFRCLS 

       310        320        330        340        350        360 
NRCALMTKEG PAPQRGKICM DMCMIDLTGK MGVDVGSEVE VFGKQNSIND LAALAGTIPY 

       370        380 
ELTCAVSKRV PRIYIRNGKV VEKELLLRG

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References

[1]"Bi-directional cross-talk between a Clostridium symbiont, Roseburia hominis, the gut immune system and appetite regulation."
Mulder I.E., Aminov R.I., Travis A.J., Lan A., Gaboriau-Routhiau V., Garden K., Logan E., Delday M., Coutts A.G.P., Grant G., Patterson A.M., Cerf-Bensussan N., Kelly D.
Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16839 / NCIMB 14029 / A2-183.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003040 Genomic DNA. Translation: AEN98302.1.
RefSeqYP_004840234.1. NC_015977.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEN98302; AEN98302; RHOM_15980.
GeneID11148714.
KEGGrho:RHOM_15980.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycRHOM585394:GHYQ-3173-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2T5Z4_ROSHA
AccessionPrimary (citable) accession number: G2T5Z4
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 3, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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