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G2T125

- G2T125_ROSHA

UniProt

G2T125 - G2T125_ROSHA

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Protein
Anaerobic ribonucleoside-triphosphate reductase-activating protein
Gene
RHOM_04870
Organism
Roseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine By similarity.UniRule annotation

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: InterPro
  2. [formate-C-acetyltransferase]-activating enzyme activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciRHOM585394:GHYQ-1003-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic ribonucleoside-triphosphate reductase-activating proteinUniRule annotation (EC:1.97.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:RHOM_04870Imported
OrganismiRoseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)Imported
Taxonomic identifieri585394 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeRoseburia
ProteomesiUP000008178: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliG2T125.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK04068.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR012837. NrdG.
[Graphical view]
PIRSFiPIRSF000368. NrdG. 1 hit.
TIGRFAMsiTIGR02491. NrdG. 1 hit.

Sequencei

Sequence statusi: Complete.

G2T125-1 [UniParc]FASTAAdd to Basket

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MNYSAIKYCD IANGTGVRTV LFVSGCRNHC KDCFQPETWA FEYGNPFTGE    50
VEDEIIASLK PDYIRGLTLL GGDPFEPENQ KALLPFMRRV KAECPGKDVW 100
AYTGYVLDRD LVPGGKCCTA DTAELLHMID VLVDGPFVTE LHDISLLFKG 150
SSNQRVIDCA EYCRSGEIRE LM 172
Length:172
Mass (Da):19,228
Last modified:November 16, 2011 - v1
Checksum:iBAE75DB4942CF1E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003040 Genomic DNA. Translation: AEN96094.1.
RefSeqiWP_014079139.1. NC_015977.1.
YP_004838026.1. NC_015977.1.

Genome annotation databases

EnsemblBacteriaiAEN96094; AEN96094; RHOM_04870.
GeneIDi11148450.
KEGGirho:RHOM_04870.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003040 Genomic DNA. Translation: AEN96094.1 .
RefSeqi WP_014079139.1. NC_015977.1.
YP_004838026.1. NC_015977.1.

3D structure databases

ProteinModelPortali G2T125.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN96094 ; AEN96094 ; RHOM_04870 .
GeneIDi 11148450.
KEGGi rho:RHOM_04870.

Phylogenomic databases

KOi K04068.

Enzyme and pathway databases

BioCyci RHOM585394:GHYQ-1003-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR012837. NrdG.
[Graphical view ]
PIRSFi PIRSF000368. NrdG. 1 hit.
TIGRFAMsi TIGR02491. NrdG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Bi-directional cross-talk between a Clostridium symbiont, Roseburia hominis, the gut immune system and appetite regulation."
    Mulder I.E., Aminov R.I., Travis A.J., Lan A., Gaboriau-Routhiau V., Garden K., Logan E., Delday M., Coutts A.G.P., Grant G., Patterson A.M., Cerf-Bensussan N., Kelly D.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16839 / NCIMB 14029 / A2-183.

Entry informationi

Entry nameiG2T125_ROSHA
AccessioniPrimary (citable) accession number: G2T125
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 3, 2014
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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