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G2T125

- G2T125_ROSHA

UniProt

G2T125 - G2T125_ROSHA

Protein

Anaerobic ribonucleoside-triphosphate reductase-activating protein

Gene

RHOM_04870

Organism
Roseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.UniRule annotation

    GO - Molecular functioni

    1. [formate-C-acetyltransferase]-activating enzyme activity Source: InterPro
    2. 4 iron, 4 sulfur cluster binding Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Enzyme and pathway databases

    BioCyciRHOM585394:GHYQ-1003-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Anaerobic ribonucleoside-triphosphate reductase-activating proteinUniRule annotation (EC:1.97.1.-UniRule annotation)
    Gene namesi
    Ordered Locus Names:RHOM_04870Imported
    OrganismiRoseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)Imported
    Taxonomic identifieri585394 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeRoseburia
    ProteomesiUP000008178: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliG2T125.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the organic radical-activating enzymes family.UniRule annotation

    Phylogenomic databases

    KOiK04068.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR012837. NrdG.
    [Graphical view]
    PIRSFiPIRSF000368. NrdG. 1 hit.
    TIGRFAMsiTIGR02491. NrdG. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G2T125-1 [UniParc]FASTAAdd to Basket

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    MNYSAIKYCD IANGTGVRTV LFVSGCRNHC KDCFQPETWA FEYGNPFTGE    50
    VEDEIIASLK PDYIRGLTLL GGDPFEPENQ KALLPFMRRV KAECPGKDVW 100
    AYTGYVLDRD LVPGGKCCTA DTAELLHMID VLVDGPFVTE LHDISLLFKG 150
    SSNQRVIDCA EYCRSGEIRE LM 172
    Length:172
    Mass (Da):19,228
    Last modified:November 16, 2011 - v1
    Checksum:iBAE75DB4942CF1E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003040 Genomic DNA. Translation: AEN96094.1.
    RefSeqiWP_014079139.1. NC_015977.1.
    YP_004838026.1. NC_015977.1.

    Genome annotation databases

    EnsemblBacteriaiAEN96094; AEN96094; RHOM_04870.
    GeneIDi11148450.
    KEGGirho:RHOM_04870.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003040 Genomic DNA. Translation: AEN96094.1 .
    RefSeqi WP_014079139.1. NC_015977.1.
    YP_004838026.1. NC_015977.1.

    3D structure databases

    ProteinModelPortali G2T125.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEN96094 ; AEN96094 ; RHOM_04870 .
    GeneIDi 11148450.
    KEGGi rho:RHOM_04870.

    Phylogenomic databases

    KOi K04068.

    Enzyme and pathway databases

    BioCyci RHOM585394:GHYQ-1003-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR012837. NrdG.
    [Graphical view ]
    PIRSFi PIRSF000368. NrdG. 1 hit.
    TIGRFAMsi TIGR02491. NrdG. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Bi-directional cross-talk between a Clostridium symbiont, Roseburia hominis, the gut immune system and appetite regulation."
      Mulder I.E., Aminov R.I., Travis A.J., Lan A., Gaboriau-Routhiau V., Garden K., Logan E., Delday M., Coutts A.G.P., Grant G., Patterson A.M., Cerf-Bensussan N., Kelly D.
      Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16839 / NCIMB 14029 / A2-183Imported.

    Entry informationi

    Entry nameiG2T125_ROSHA
    AccessioniPrimary (citable) accession number: G2T125
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3