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G2T125

- G2T125_ROSHA

UniProt

G2T125 - G2T125_ROSHA

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Protein

Anaerobic ribonucleoside-triphosphate reductase-activating protein

Gene

RHOM_04870

Organism
Roseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.UniRule annotation

GO - Molecular functioni

  1. [formate-C-acetyltransferase]-activating enzyme activity Source: InterPro
  2. 4 iron, 4 sulfur cluster binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciRHOM585394:GHYQ-1003-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic ribonucleoside-triphosphate reductase-activating proteinUniRule annotation (EC:1.97.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:RHOM_04870Imported
OrganismiRoseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183)Imported
Taxonomic identifieri585394 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeRoseburia
ProteomesiUP000008178: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliG2T125.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the organic radical-activating enzymes family.UniRule annotation

Phylogenomic databases

KOiK04068.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR012837. NrdG.
[Graphical view]
PIRSFiPIRSF000368. NrdG. 1 hit.
TIGRFAMsiTIGR02491. NrdG. 1 hit.

Sequencei

Sequence statusi: Complete.

G2T125-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNYSAIKYCD IANGTGVRTV LFVSGCRNHC KDCFQPETWA FEYGNPFTGE
60 70 80 90 100
VEDEIIASLK PDYIRGLTLL GGDPFEPENQ KALLPFMRRV KAECPGKDVW
110 120 130 140 150
AYTGYVLDRD LVPGGKCCTA DTAELLHMID VLVDGPFVTE LHDISLLFKG
160 170
SSNQRVIDCA EYCRSGEIRE LM
Length:172
Mass (Da):19,228
Last modified:November 16, 2011 - v1
Checksum:iBAE75DB4942CF1E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003040 Genomic DNA. Translation: AEN96094.1.
RefSeqiYP_004838026.1. NC_015977.1.

Genome annotation databases

EnsemblBacteriaiAEN96094; AEN96094; RHOM_04870.
GeneIDi11148450.
KEGGirho:RHOM_04870.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003040 Genomic DNA. Translation: AEN96094.1 .
RefSeqi YP_004838026.1. NC_015977.1.

3D structure databases

ProteinModelPortali G2T125.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN96094 ; AEN96094 ; RHOM_04870 .
GeneIDi 11148450.
KEGGi rho:RHOM_04870.

Phylogenomic databases

KOi K04068.

Enzyme and pathway databases

BioCyci RHOM585394:GHYQ-1003-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR012837. NrdG.
[Graphical view ]
PIRSFi PIRSF000368. NrdG. 1 hit.
TIGRFAMsi TIGR02491. NrdG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Bi-directional cross-talk between a Clostridium symbiont, Roseburia hominis, the gut immune system and appetite regulation."
    Mulder I.E., Aminov R.I., Travis A.J., Lan A., Gaboriau-Routhiau V., Garden K., Logan E., Delday M., Coutts A.G.P., Grant G., Patterson A.M., Cerf-Bensussan N., Kelly D.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16839 / NCIMB 14029 / A2-183Imported.

Entry informationi

Entry nameiG2T125_ROSHA
AccessioniPrimary (citable) accession number: G2T125
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3