tuf

Functionⁱ

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	19 – 26	GTPUniRule annotation	8
Nucleotide bindingⁱ	84 – 88	GTPUniRule annotation	5
Nucleotide bindingⁱ	139 – 142	GTPUniRule annotation	4

GO - Molecular functionⁱ

GTPase activity Source: InterPro
GTP binding Source: UniProtKB-UniRule
translation elongation factor activity Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Elongation factorUniRule annotationImported
Biological process	Protein biosynthesis
Ligand	GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	RMAR762570:G1GZX-2077-MONOMER

BioCycⁱ

RMAR762570:G1GZX-2077-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Elongation factor TuUniRule annotation Short name: EF-TuUniRule annotation
Gene namesⁱ	Name:tufUniRule annotation ORF Names:Rhom172_2042Imported
Organismⁱ	Rhodothermus marinus SG0.5JP17-172Imported
Taxonomic identifierⁱ	762570 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › FCB group › Bacteroidetes/Chlorobi group › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Rhodothermus › Rhodothermus marinus
Proteomesⁱ	UP000001280 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Automatic assertion according to rulesⁱ
- HAMAP-Rule:MF_00118

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

CytoplasmUniRule annotation

Interactionⁱ

Subunit structureⁱ

Monomer.UniRule annotation

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	10 – 207	Tr-type GInterPro annotationAdd BLAST		198

Sequence similaritiesⁱ

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K02358
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00LA

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03697 EFTU_II, 1 hit
HAMAPⁱ	MF_00118_B EF_Tu_B, 1 hit
InterProⁱ	View protein in InterPro IPR004161 EFTu-like_2 IPR033720 EFTU_2 IPR031157 G_TR_CS IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR000795 TF_GTP-bd_dom IPR009000 Transl_B-barrel_sf IPR009001 Transl_elong_EF1A/Init_IF2_C IPR004541 Transl_elong_EFTu/EF1A_bac/org IPR004160 Transl_elong_EFTu/EF1A_C
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00009 GTP_EFTU, 1 hit PF03144 GTP_EFTU_D2, 1 hit PF03143 GTP_EFTU_D3, 1 hit
PRINTSⁱ	PR00315 ELONGATNFCT
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF50465 SSF50465, 1 hit SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00485 EF-Tu, 1 hit TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS00301 G_TR_1, 1 hit PS51722 G_TR_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

G2SFD0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAKEVFQRTK PHVNIGTIGH VDHGKTTLTA AITQVLAKRV PDPVNKPYTF 
        60         70         80         90        100
DSIDNAPEER ERGITIATAH VEYATEKRHY AHVDCPGHAD YVKNMITGAA 
       110        120        130        140        150
QMDGAILVVA ATDGPMPQTR EHILLARQVG VPYIVVFLNK VDLVDDEELL 
       160        170        180        190        200
ELVEMEVREL LSQYEFPGDE VPVIRGSALG ALNGDPQWED KIMELMNAVD 
       210        220        230        240        250
EYIPTPVREK DKPFLMPIED VFSITGRGTV VTGRIERGVV KVGDPVEIIG 
       260        270        280        290        300
LREEKLTSVV TGVEMFRKQL EQGEAGDNVG LLLRGIGKED VERGMVVCAP 
       310        320        330        340        350
GSVTPHREFE CEVYVLSKEE GGRHTPFFNG YRPQFYFRTT DVTGDITLPE 
       360        370        380        390 
GVEMVMPGDN ARFRVKLIYP VAMEEGLRFA IREGGRTVGA GVVTKILD

Length:398

Mass (Da):44,065

Last modified:November 16, 2011 - v1

Checksum:ⁱEAF11E825A12C6FB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP003029 Genomic DNA Translation: AEN73945.1
NCBI Reference Sequences More...RefSeqⁱ	WP_014067552.1, NC_015966.1

Genome annotation databases

EnsemblBacteriaⁱ	AEN73945; AEN73945; Rhom172_2042
KEGGⁱ	rmg:Rhom172_2042

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
G2SFD0	D0MHN4 A0A1M6X0R9 A0A1M6WH63 G2SHG6 D0MGV2	Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis) Rhodothermus profundi Rhodothermus marinus SG0.5JP17-172	398	UniRef90_D0MHN4	Cluster: Elongation factor Tu	6

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
G2SFD0	Q5HRK4 Q8CQ81 A0A111AHD3 A0A0N0LYN4 A0A1J4HF97 A0A0E1VH70 D4FMQ7 G0YCC1 D7R4J4 D7R4J1 +5826	Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Staphylococcus epidermidis (strain ATCC 12228) Streptococcus pneumoniae Staphylococcus epidermidis Staphylococcus sp. HMSC34G04 Staphylococcus epidermidis W23144 Staphylococcus epidermidis M23864:W2(grey) uncultured Staphylococcus sp. human gut metagenome Staphylococcus devriesei And more	394	UniRef50_Q5HRK4	Cluster: Elongation factor Tu	5,837

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP003029 Genomic DNA Translation: AEN73945.1
NCBI Reference Sequences More...RefSeqⁱ	WP_014067552.1, NC_015966.1

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AEN73945; AEN73945; Rhom172_2042
KEGGⁱ	rmg:Rhom172_2042

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K02358
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00LA

Enzyme and pathway databases

BioCycⁱ	RMAR762570:G1GZX-2077-MONOMER

BioCycⁱ

RMAR762570:G1GZX-2077-MONOMER

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03697 EFTU_II, 1 hit
HAMAPⁱ	MF_00118_B EF_Tu_B, 1 hit
InterProⁱ	View protein in InterPro IPR004161 EFTu-like_2 IPR033720 EFTU_2 IPR031157 G_TR_CS IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR000795 TF_GTP-bd_dom IPR009000 Transl_B-barrel_sf IPR009001 Transl_elong_EF1A/Init_IF2_C IPR004541 Transl_elong_EFTu/EF1A_bac/org IPR004160 Transl_elong_EFTu/EF1A_C
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00009 GTP_EFTU, 1 hit PF03144 GTP_EFTU_D2, 1 hit PF03143 GTP_EFTU_D3, 1 hit
PRINTSⁱ	PR00315 ELONGATNFCT
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF50465 SSF50465, 1 hit SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00485 EF-Tu, 1 hit TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS00301 G_TR_1, 1 hit PS51722 G_TR_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	G2SFD0_RHOMR
Accessionⁱ	G2SFD0Primary (citable) accession number: G2SFD0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 16, 2011
	Last sequence update:	November 16, 2011
	Last modified:	March 28, 2018
	This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - G2SFD0 (G2SFD0_RHOMR)

Your basket is currently empty. ⁱ

Elongation factor Tu

Select a section on the left to see content.

Functionⁱ

Regions

GO - Molecular functionⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Subunit structureⁱ

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - G2SFD0 (G2SFD0_RHOMR)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Elongation factor Tu

tuf

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ