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G2RBC7

- G2RBC7_THITE

UniProt

G2RBC7 - G2RBC7_THITE

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Protein

DNA ligase

Gene

THITE_2080045

Organism
Thielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium alabamense)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:THITE_2080045Imported
OrganismiThielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium alabamense)Imported
Taxonomic identifieri578455 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeThielavia
ProteomesiUP000008181: Chromosome 4

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2RBC7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSRTKRAKS PDVDAIEEDE KQYGSGPLTL EELDEQFPNR PRNHSKTPPF
60 70 80 90 100
SDLFQSLFNP LIDCKPSTAG AASAPARARA RARAGPSFSS SSSSTKLSYH
110 120 130 140 150
EQRRHIIERF MARWRADVGP DFYPAMRLIL PDKDRDRGVY GLKENTIGKL
160 170 180 190 200
LVKVMKIDRN SEDGYALMHW KLPGHAGGGG GRFGGGAGGG GGGGSRGSAG
210 220 230 240 250
DFAGRCFEIV SKRQMRTEPG NFTIGEVNVM LDRLAGASGE AEQLPIFEEF
260 270 280 290 300
YQGMNAEELM WLVRIILKDM KVGATERTFL GLWHPDAEAL FSVSSSLRRV
310 320 330 340 350
CWELYDPEFR LEQQETGVTL MSCFQPQLAQ FQMTTTFAKL VANLGVTEEN
360 370 380 390 400
PEFWIEEKLD GERMQMHMQE DDSVPGGYRF AFWSRKAKDY TYLYGSGLED
410 420 430 440 450
DNSALTRHLK NAFHSGVRNL ILDGEMITWD PEVDKIVPFG TLKTAALEQQ
460 470 480 490 500
KNPFQNGPRP LYRVFDILLL NDKSLTEYTL ADRHRALERA VKGEPRRLEI
510 520 530 540 550
HPYETATSAD AIEPLLRKVV AEASEGLVLK NPRSRYQLNS RNNDWIKVKP
560 570 580 590 600
EYMSEFGESL DCVVIGGYYG SGRRGGTLSS FLCGVRVSEN FVKSGAAASR
610 620 630 640 650
EKCLSFCKVG GGFKAEDYGE IRHHTEGKWR DWDAANPPSE FIELGGGERL
660 670 680 690 700
QYERPDVWIR PSESVVLSVK AASFAPSDQF ATGWTLRFPR FRKLRLDKAW
710 720 730 740 750
DAAMDVDECE ALRTKVKQEE KERKAMEMES RKRRPTKRQK RELVIAGAAD
760 770 780 790 800
PAATAATATA TAEFLDVKTP RSELFRGLDF CVLSEMLRPR KMTKPELEKL
810 820 830 840 850
LKENGGRIHQ TVDKGSGMIL LADKNVVKVA SLKKAGDADI VRPKWVLDCL
860 870 880 890 900
EQGGGEGYLL PFEEGHLLFA TEEMRRVAEE NTDQYGDSYA RDVGIDELRA
910 920 930 940 950
ILDAMDMPDG GGAEFDVSQF LDQLEEHGNG LEDLKSFMFR RCRMYFALGD
960 970 980 990 1000
GVPETTALRL GNYVKFGSGE VADGVEDEKI THVVVVGGEQ DTAASEKVLA
1010 1020 1030 1040
ADVRYRVSSR RAVPRIVSSR WVEDCWKEGT LVDEEAYAPN
Length:1,040
Mass (Da):116,374
Last modified:November 16, 2011 - v1
Checksum:iF35809FF60A6B6F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003012 Genomic DNA. Translation: AEO69098.1.
RefSeqiXP_003655434.1. XM_003655386.1.

Genome annotation databases

GeneIDi11520347.
KEGGittt:THITE_2080045.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003012 Genomic DNA. Translation: AEO69098.1 .
RefSeqi XP_003655434.1. XM_003655386.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 11520347.
KEGGi ttt:THITE_2080045.

Phylogenomic databases

KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
PANTHERi PTHR10459:SF7. PTHR10459:SF7. 1 hit.
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 38088 / NRRL 8126Imported.

Entry informationi

Entry nameiG2RBC7_THITE
AccessioniPrimary (citable) accession number: G2RBC7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3