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G2RBC7

- G2RBC7_THITE

UniProt

G2RBC7 - G2RBC7_THITE

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Protein
DNA ligase
Gene
THITE_2080045
Organism
Thielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium alabamense)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:THITE_2080045Imported
OrganismiThielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium alabamense)
Taxonomic identifieri578455 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeThielavia
ProteomesiUP000008181: Chromosome 4

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2RBC7-1 [UniParc]FASTAAdd to Basket

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MSSRTKRAKS PDVDAIEEDE KQYGSGPLTL EELDEQFPNR PRNHSKTPPF     50
SDLFQSLFNP LIDCKPSTAG AASAPARARA RARAGPSFSS SSSSTKLSYH 100
EQRRHIIERF MARWRADVGP DFYPAMRLIL PDKDRDRGVY GLKENTIGKL 150
LVKVMKIDRN SEDGYALMHW KLPGHAGGGG GRFGGGAGGG GGGGSRGSAG 200
DFAGRCFEIV SKRQMRTEPG NFTIGEVNVM LDRLAGASGE AEQLPIFEEF 250
YQGMNAEELM WLVRIILKDM KVGATERTFL GLWHPDAEAL FSVSSSLRRV 300
CWELYDPEFR LEQQETGVTL MSCFQPQLAQ FQMTTTFAKL VANLGVTEEN 350
PEFWIEEKLD GERMQMHMQE DDSVPGGYRF AFWSRKAKDY TYLYGSGLED 400
DNSALTRHLK NAFHSGVRNL ILDGEMITWD PEVDKIVPFG TLKTAALEQQ 450
KNPFQNGPRP LYRVFDILLL NDKSLTEYTL ADRHRALERA VKGEPRRLEI 500
HPYETATSAD AIEPLLRKVV AEASEGLVLK NPRSRYQLNS RNNDWIKVKP 550
EYMSEFGESL DCVVIGGYYG SGRRGGTLSS FLCGVRVSEN FVKSGAAASR 600
EKCLSFCKVG GGFKAEDYGE IRHHTEGKWR DWDAANPPSE FIELGGGERL 650
QYERPDVWIR PSESVVLSVK AASFAPSDQF ATGWTLRFPR FRKLRLDKAW 700
DAAMDVDECE ALRTKVKQEE KERKAMEMES RKRRPTKRQK RELVIAGAAD 750
PAATAATATA TAEFLDVKTP RSELFRGLDF CVLSEMLRPR KMTKPELEKL 800
LKENGGRIHQ TVDKGSGMIL LADKNVVKVA SLKKAGDADI VRPKWVLDCL 850
EQGGGEGYLL PFEEGHLLFA TEEMRRVAEE NTDQYGDSYA RDVGIDELRA 900
ILDAMDMPDG GGAEFDVSQF LDQLEEHGNG LEDLKSFMFR RCRMYFALGD 950
GVPETTALRL GNYVKFGSGE VADGVEDEKI THVVVVGGEQ DTAASEKVLA 1000
ADVRYRVSSR RAVPRIVSSR WVEDCWKEGT LVDEEAYAPN 1040
Length:1,040
Mass (Da):116,374
Last modified:November 16, 2011 - v1
Checksum:iF35809FF60A6B6F0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003012 Genomic DNA. Translation: AEO69098.1.
RefSeqiXP_003655434.1. XM_003655386.1.

Genome annotation databases

GeneIDi11520347.
KEGGittt:THITE_2080045.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003012 Genomic DNA. Translation: AEO69098.1 .
RefSeqi XP_003655434.1. XM_003655386.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 11520347.
KEGGi ttt:THITE_2080045.

Phylogenomic databases

KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 38088 / NRRL 8126.

Entry informationi

Entry nameiG2RBC7_THITE
AccessioniPrimary (citable) accession number: G2RBC7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: December 11, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi