ID   G2R806_THETT            Unreviewed;       547 AA.
AC   G2R806;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AEO68065.1};
GN   ORFNames=THITE_2117395 {ECO:0000313|EMBL:AEO68065.1};
OS   Thermothielavioides terrestris (strain ATCC 38088 / NRRL 8126) (Thielavia
OS   terrestris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Thermothielavioides;
OC   Thermothielavioides terrestris.
OX   NCBI_TaxID=578455 {ECO:0000313|EMBL:AEO68065.1, ECO:0000313|Proteomes:UP000008181};
RN   [1] {ECO:0000313|EMBL:AEO68065.1, ECO:0000313|Proteomes:UP000008181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 38088 / NRRL 8126 {ECO:0000313|Proteomes:UP000008181};
RX   PubMed=21964414; DOI=10.1038/nbt.1976;
RA   Berka R.M., Grigoriev I.V., Otillar R., Salamov A., Grimwood J., Reid I.,
RA   Ishmael N., John T., Darmond C., Moisan M.-C., Henrissat B., Coutinho P.M.,
RA   Lombard V., Natvig D.O., Lindquist E., Schmutz J., Lucas S., Harris P.,
RA   Powlowski J., Bellemare A., Taylor D., Butler G., de Vries R.P.,
RA   Allijn I.E., van den Brink J., Ushinsky S., Storms R., Powell A.J.,
RA   Paulsen I.T., Elbourne L.D.H., Baker S.E., Magnuson J., LaBoissiere S.,
RA   Clutterbuck A.J., Martinez D., Wogulis M., de Leon A.L., Rey M.W.,
RA   Tsang A.;
RT   "Comparative genomic analysis of the thermophilic biomass-degrading fungi
RT   Myceliophthora thermophila and Thielavia terrestris.";
RL   Nat. Biotechnol. 29:922-927(2011).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU000382}.
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DR   EMBL; CP003011; AEO68065.1; -; Genomic_DNA.
DR   RefSeq; XP_003654401.1; XM_003654353.1.
DR   AlphaFoldDB; G2R806; -.
DR   STRING; 578455.G2R806; -.
DR   GeneID; 11516424; -.
DR   KEGG; ttt:THITE_2117395; -.
DR   eggNOG; KOG0629; Eukaryota.
DR   HOGENOM; CLU_011856_0_0_1; -.
DR   OrthoDB; 888358at2759; -.
DR   Proteomes; UP000008181; Chromosome 3.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.170; -; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR45677:SF8; CYSTEINE SULFINIC ACID DECARBOXYLASE; 1.
DR   PANTHER; PTHR45677; GLUTAMATE DECARBOXYLASE-RELATED; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008181}.
FT   REGION          359..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..386
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         324
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   547 AA;  57984 MW;  E01A0DD70A19DE35 CRC64;
     MNGVHDGQPL NRADEVEHLI DAVKALILPF IRAADEAVPS RAAGELLPNK EGVVQNALVN
     ARKPEDLVRE LSLCLPEGPG LGEDGLLRAI GDILKYSVNT WDQGFMDKLY ASTNPVGVVS
     ELLLGVLNTN VHVYQVSPAL TVIEKHTAQK LARLFGFTGP RAGGITCQGG SSSNLTSIVI
     ARNTLYPESK TRGNQCATGS FILFTSEHGH YSVEKAAVTC GLGSSSVWTV PVDDAGRMDP
     SALRRLVQRA RAEGNTPLYV NATAGTTVLG SYDPIEAVAA VCREFGLWLH VDASWGGPAI
     FSPRHRHKLA GAHLANSLTV NPHKMLNVPV TCSFLLGPDT AVFHRANTLP AGYLFHSTAS
     SAPNPPQPAT TITTTTTPTT ATPPTPAENG EEDGPPEEEV WDLADLTLQC GRRADSLKLF
     LAWTYHGAGG FAAQVDRGFA AAARLAELVA AHPDLAPVSP SPPPCLQVCF YYAPRGELAA
     DPAENTRRTR AVVHALVGRG FMVDYAPGKR GAFLRVVVNS LTLRGTVEGL VKAVAAVGRE
     VVGGFLN
//