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Protein

Hexokinase

Gene

MYCTH_2297364

Organism
Thielavia heterothallica (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Myceliophthora thermophila)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:MYCTH_2297364Imported
OrganismiThielavia heterothallica (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Myceliophthora thermophila)Imported
Taxonomic identifieri573729 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeMyceliophthora
ProteomesiUP000007322 Componenti: Chromosome 1

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

InParanoidiG2Q5I7.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2Q5I7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALEAETQAI VDQFEFSDDD VNRAVKEFLR QMDEGLRKDG TSLSQIPTYV
60 70 80 90 100
TAVPNGSEKG LYMAVDLGGT NFRVCSIQLL GNNSFRHTYN KVAIPKHLMV
110 120 130 140 150
AKTAQELFAF LALEIKKFLQ EHHNEDFEHH IRRRMTVSAP EGFRDEHIFR
160 170 180 190 200
MGFTFSFPVK QVGINKGTLI RWTKGFDIPD AVGKDVCALL QEEIDKLHLP
210 220 230 240 250
VKVAALVNDT VGTLMARSYT SPNKHGSILG AIFGTGTNGA YIEKLSNLKK
260 270 280 290 300
GLAGEYDDTT GHMVINTEWG SFDNQLNVLP TTKWDDALEK GSINPGYQMY
310 320 330 340 350
EKRVSGMFLG EILRLVTLEL HNNPNVSFFK DENSSFNDRG SVTVIDRDSP
360 370 380 390 400
LYKPWGVDTS IMSTAEADHD PELSALRQSL EKDLKIYAPA YEDALAFKRI
410 420 430 440 450
SHAIGRRAAR LAAVAIAAVV IQTGKLDDPE LLGEEIDIGV DGSLVEHYPG
460 470 480 490 500
FRSMITEALK ITEGIGESAN RIKIGLTQDG SGVGAALIAS VAASMEKNTS
510 520
NVDYIGELRS TVKAEPSAVD EKAASD
Length:526
Mass (Da):57,821
Last modified:November 15, 2011 - v1
Checksum:i5662A040DD65D156
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003002 Genomic DNA. Translation: AEO54620.1.
RefSeqiXP_003659865.1. XM_003659817.1.

Genome annotation databases

GeneIDi11508927.
KEGGimtm:MYCTH_2297364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003002 Genomic DNA. Translation: AEO54620.1.
RefSeqiXP_003659865.1. XM_003659817.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11508927.
KEGGimtm:MYCTH_2297364.

Phylogenomic databases

InParanoidiG2Q5I7.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42464 / BCRC 31852 / DSM 1799Imported.

Entry informationi

Entry nameiG2Q5I7_THIHA
AccessioniPrimary (citable) accession number: G2Q5I7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 15, 2011
Last sequence update: November 15, 2011
Last modified: March 31, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.