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G2Q355

- G2Q355_THIHA

UniProt

G2Q355 - G2Q355_THIHA

Protein

Histone deacetylase

Gene

MYCTH_62332

Organism
Thielavia heterothallica (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Myceliophthora thermophila)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    ORF Names:MYCTH_62332Imported
    OrganismiThielavia heterothallica (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Myceliophthora thermophila)Imported
    Taxonomic identifieri573729 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeMyceliophthora
    ProteomesiUP000007322: Chromosome 1

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG2Q355.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    KOiK11483.
    OrthoDBiEOG78M0B2.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    G2Q355-1 [UniParc]FASTAAdd to Basket

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    MDVSAYQYRP PKPNYLPHNI EADDPIVEEY AVPLGKADDR ENAIFFNKMK    50
    FAAQEYGIVR PKGYRVSYHA TPEMEKHHFG QTHPMKPWRL TLTKSLVTSY 100
    GMPFAMDNYV TREATYEELN AFHSSDYLDY LSTATPEDQP QDIDNSDKEV 150
    KYNLGGSDCP LFHGLYNYCS MSAGCSLDAA RKITNNQSDI AIAWGGGLHH 200
    AKKYEASGFC YINDIVLAIL QLLRIYPRVL YIDIDVHHGD GVEEAFYSTD 250
    RVMTVSFHKY HPETFFPGTG ALEDNGPKSE HNPGAHHAIN VPLQDGITDE 300
    QYENLFQSII GPINERYRPS AIALQCGADS LAGDRLGRFN LRVQGHGACV 350
    RYCKSLGLPM IMFGGGGYTP RNVARAWAYE TSIAIGADTR IPETIPEHAP 400
    WREHFIHDTL FPTLEQSMNE PRHNRNSDKR LREIVAHVHE QLRFVSHAPS 450
    VQSTIIPPDL GPIRDDVEAR LKEESEEKDG GLRKIQEEGL GQEGEF 496
    Length:496
    Mass (Da):55,958
    Last modified:November 16, 2011 - v1
    Checksum:i2F0C1E2F03AF0E69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003002 Genomic DNA. Translation: AEO53518.1.
    RefSeqiXP_003658763.1. XM_003658715.1.

    Genome annotation databases

    GeneIDi11506047.
    KEGGimtm:MYCTH_62332.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003002 Genomic DNA. Translation: AEO53518.1 .
    RefSeqi XP_003658763.1. XM_003658715.1.

    3D structure databases

    ProteinModelPortali G2Q355.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 11506047.
    KEGGi mtm:MYCTH_62332.

    Phylogenomic databases

    KOi K11483.
    OrthoDBi EOG78M0B2.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 42464 / BCRC 31852 / DSM 1799Imported.

    Entry informationi

    Entry nameiG2Q355_THIHA
    AccessioniPrimary (citable) accession number: G2Q355
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3