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G2PX59 (G2PX59_9FIRM) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thymidylate kinase HAMAP-Rule MF_00165
EC=2.7.4.9 HAMAP-Rule MF_00165
Alternative name(s):
dTMP kinase HAMAP-Rule MF_00165
Gene names
Name:tmk HAMAP-Rule MF_00165
ORF Names:Calla_1208 EMBL AEM73838.1
OrganismCaldicellulosiruptor lactoaceticus 6A EMBL AEM73838.1
Taxonomic identifier632516 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Caldicellulosiruptor ›

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis By similarity. HAMAP-Rule MF_00165

Catalytic activity

ATP + dTMP = ADP + dTDP. SAAS SAAS018095 HAMAP-Rule MF_00165

Sequence similarities

Belongs to the thymidylate kinase family. HAMAP-Rule MF_00165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding11 – 188ATP By similarity HAMAP-Rule MF_00165

Sequences

Sequence LengthMass (Da)Tools
G2PX59 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 23B2634B6B9D3318

FASTA20723,836
        10         20         30         40         50         60 
MRKGKLIVFE GNDGSGKTTQ LVKVEKYLKE KGYKVLTTRE PGGTEVGYRI RKLLLDPQYK 

        70         80         90        100        110        120 
MDGLTEALLL AADRNEHVKN VLIPALDEGY IVLCDRYILS SVVYQGIVRG VGVENILRLN 

       130        140        150        160        170        180 
SIFEDRIKPD LYIVLTLEPE IALQRIKIAG KTDRLDLEDL EFHRRVYSGF KEVSKWFERC 

       190        200 
VNIEAQGSEK EVFEKVLYEI ERLLVNK

« Hide

References

[1]"Complete sequence of Caldicellulosiruptor lactoaceticus 6A."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Blumer-Schuette S.E., Kelly R.M., Woyke T.
Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 6A EMBL AEM73838.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003001 Genomic DNA. Translation: AEM73838.1.
RefSeqYP_004798815.1. NC_015949.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEM73838; AEM73838; Calla_1208.
GeneID11105249.
KEGGclc:Calla_1208.

Phylogenomic databases

KOK00943.

Enzyme and pathway databases

BioCycCLAC632516:GHP3-1241-MONOMER.

Family and domain databases

HAMAPMF_00165. Thymidylate_kinase.
InterProIPR018095. Thymidylate_kin_CS.
IPR018094. Thymidylate_kinase.
[Graphical view]
PANTHERPTHR10344. PTHR10344. 1 hit.
TIGRFAMsTIGR00041. DTMP_kinase. 1 hit.
PROSITEPS01331. THYMIDYLATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2PX59_9FIRM
AccessionPrimary (citable) accession number: G2PX59
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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