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G2PNV6

- G2PNV6_MURRD

UniProt

G2PNV6 - G2PNV6_MURRD

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Protein

Thymidine kinase

Gene

tdk

Organism
Muricauda ruestringensis (strain DSM 13258 / LMG 19739 / B1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATPUniRule annotation
Nucleotide bindingi93 – 964ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMRUE886377:GI6V-1263-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Murru_1248Imported
OrganismiMuricauda ruestringensis (strain DSM 13258 / LMG 19739 / B1)Imported
Taxonomic identifieri886377 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeMuricauda
ProteomesiUP000008908: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiQAICLSC.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

G2PNV6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFLENTVNPK EQFGWIEVIC GSMFSGKTEE LIRRLKRAQF AKQKVEIFKP
60 70 80 90 100
IVDRRYHEEM VVSHDSNEIR STPVPAAANI RLLADDCEVV GIDEAQFFDD
110 120 130 140 150
EIVTVCNDLA NRGVRVVVAG LDMDFKGNPF GPMPALMATA EYVTKVHAVC
160 170 180 190 200
TRTGNLANYS FRKSLNDNLV LLGETEEYEP LSRAAFYKAM LREKIKEMDV
210
ESEEVGTKKK KSNE
Length:214
Mass (Da):24,232
Last modified:November 16, 2011 - v1
Checksum:i49116301C59F0B59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002999 Genomic DNA. Translation: AEM70291.1.
RefSeqiYP_004787713.1. NC_015945.1.

Genome annotation databases

EnsemblBacteriaiAEM70291; AEM70291; Murru_1248.
GeneIDi11054070.
KEGGimrs:Murru_1248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002999 Genomic DNA. Translation: AEM70291.1 .
RefSeqi YP_004787713.1. NC_015945.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEM70291 ; AEM70291 ; Murru_1248 .
GeneIDi 11054070.
KEGGi mrs:Murru_1248.

Phylogenomic databases

KOi K00857.
OMAi QAICLSC.

Enzyme and pathway databases

BioCyci MRUE886377:GI6V-1263-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13258 / LMG 19739 / B1Imported.

Entry informationi

Entry nameiG2PNV6_MURRD
AccessioniPrimary (citable) accession number: G2PNV6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3