Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

G2PB79 (G2PB79_STRVO) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
ORF Names:Strvi_0343 EMBL AEM80131.1
OrganismStreptomyces violaceusniger Tu 4113 [Complete proteome] EMBL AEM80131.1
Taxonomic identifier653045 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617 HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2101N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2081ATP By similarity HAMAP-Rule MF_00407
Binding site2151ATP By similarity HAMAP-Rule MF_00407
Binding site2301ATP By similarity HAMAP-Rule MF_00407
Binding site2591ATP By similarity HAMAP-Rule MF_00407
Binding site2991ATP By similarity HAMAP-Rule MF_00407
Binding site3771ATP By similarity HAMAP-Rule MF_00407
Binding site3831ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
G2PB79 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: ED101FB05D7D9559

FASTA51254,947
        10         20         30         40         50         60 
MLLADVALTS RQVAATSARS EKIAALARLF RRTEPAEAAV VITYLAGKLP QRRTGVGWST 

        70         80         90        100        110        120 
LRHRQEPAAE PTLAVLDVDE ALTRVAAVSG TGATAARKRL VGELLAAATK EEQGFLLGLI 

       130        140        150        160        170        180 
GGELRQGALE GLAVEGLAQA VGAPAAEVRR AVMVGGSLGT VAEALLARGP EALAGFRLEV 

       190        200        210        220        230        240 
GRPVLPMLAQ SAKDLDEAID RLGPCAVEEK LDGIRVQVHR DGEDVRIYTR TLDEITDRLP 

       250        260        270        280        290        300 
EVVTAARELA VDRAILDGEV ILLDGEGRPR PFQETSARVG SRLDVAGASA ALPLSPVFFD 

       310        320        330        340        350        360 
LLVVDDRDLL DLPARERHAE LARIAPGPRR VRRLVTDDPA DPETRRAARE FAADVLARGH 

       370        380        390        400        410        420 
EGVLVKALEA PYGAGRRGAS WLKVKPVHTL DLVVLAAEWG HGRRTGKLSN LHLGARAADG 

       430        440        450        460        470        480 
TYLMLGKTFK GLTDAMLEWQ TQALLGIAVS DDGWVVRVRP ELVVEVAFDG LQRSSRYPAG 

       490        500        510 
VTLRFARVLR YREDKPADQA DTVEAVLALR GE 

« Hide

References

[1]"Complete sequence of chromosome of Streptomyces violaceusniger Tu 4113."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ivanova N., Daligault H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hagen A. expand/collapse author list , Katz L., Fiedler H.-P., Keasling J., Fortman J., Woyke T.
Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Tu 4113 EMBL AEM80131.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002994 Genomic DNA. Translation: AEM80131.1.
RefSeqYP_004810411.1. NC_015957.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEM80131; AEM80131; Strvi_0343.
GeneID11088841.
KEGGsvl:Strvi_0343.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01971.

Enzyme and pathway databases

BioCycSVIO653045:GHK6-96-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2PB79_STRVO
AccessionPrimary (citable) accession number: G2PB79
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 19, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)