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G2PB79

- G2PB79_STRVO

UniProt

G2PB79 - G2PB79_STRVO

Protein

Probable DNA ligase

Gene

lig

Organism
Streptomyces violaceusniger Tu 4113
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei208 – 2081ATPUniRule annotation
    Active sitei210 – 2101N6-AMP-lysine intermediateUniRule annotation
    Binding sitei215 – 2151ATPUniRule annotation
    Binding sitei230 – 2301ATPUniRule annotation
    Binding sitei259 – 2591ATPUniRule annotation
    Binding sitei299 – 2991ATPUniRule annotation
    Binding sitei377 – 3771ATPUniRule annotation
    Binding sitei383 – 3831ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSVIO653045:GHK6-96-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligUniRule annotation
    ORF Names:Strvi_0343Imported
    OrganismiStreptomyces violaceusniger Tu 4113Imported
    Taxonomic identifieri653045 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000008703: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK01971.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G2PB79-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLADVALTS RQVAATSARS EKIAALARLF RRTEPAEAAV VITYLAGKLP    50
    QRRTGVGWST LRHRQEPAAE PTLAVLDVDE ALTRVAAVSG TGATAARKRL 100
    VGELLAAATK EEQGFLLGLI GGELRQGALE GLAVEGLAQA VGAPAAEVRR 150
    AVMVGGSLGT VAEALLARGP EALAGFRLEV GRPVLPMLAQ SAKDLDEAID 200
    RLGPCAVEEK LDGIRVQVHR DGEDVRIYTR TLDEITDRLP EVVTAARELA 250
    VDRAILDGEV ILLDGEGRPR PFQETSARVG SRLDVAGASA ALPLSPVFFD 300
    LLVVDDRDLL DLPARERHAE LARIAPGPRR VRRLVTDDPA DPETRRAARE 350
    FAADVLARGH EGVLVKALEA PYGAGRRGAS WLKVKPVHTL DLVVLAAEWG 400
    HGRRTGKLSN LHLGARAADG TYLMLGKTFK GLTDAMLEWQ TQALLGIAVS 450
    DDGWVVRVRP ELVVEVAFDG LQRSSRYPAG VTLRFARVLR YREDKPADQA 500
    DTVEAVLALR GE 512
    Length:512
    Mass (Da):54,947
    Last modified:November 16, 2011 - v1
    Checksum:iED101FB05D7D9559
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002994 Genomic DNA. Translation: AEM80131.1.
    RefSeqiWP_014053655.1. NC_015957.1.
    YP_004810411.1. NC_015957.1.

    Genome annotation databases

    EnsemblBacteriaiAEM80131; AEM80131; Strvi_0343.
    GeneIDi11088841.
    KEGGisvl:Strvi_0343.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002994 Genomic DNA. Translation: AEM80131.1 .
    RefSeqi WP_014053655.1. NC_015957.1.
    YP_004810411.1. NC_015957.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEM80131 ; AEM80131 ; Strvi_0343 .
    GeneIDi 11088841.
    KEGGi svl:Strvi_0343.

    Phylogenomic databases

    KOi K01971.

    Enzyme and pathway databases

    BioCyci SVIO653045:GHK6-96-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Streptomyces violaceusniger Tu 4113."
      US DOE Joint Genome Institute
      Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ivanova N., Daligault H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hagen A.
      , Katz L., Fiedler H.-P., Keasling J., Fortman J., Woyke T.
      Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Tu 4113Imported.

    Entry informationi

    Entry nameiG2PB79_STRVO
    AccessioniPrimary (citable) accession number: G2PB79
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3